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European Archives of Oto-Rhino-Laryngology

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01-10-2018 | Otology

Gradient impact of cognitive decline in unilateral vestibular hypofunction after rehabilitation: preliminary findings

Authors: Alessandro Micarelli, Andrea Viziano, Ernesto Bruno, Elisa Micarelli, Ivan Augimeri, Marco Alessandrini

Published in: European Archives of Oto-Rhino-Laryngology | Issue 10/2018

Abstract

Purpose

Considering recent advances in central cognitive- and age-related processing interfering with balance and sensory reweighting in uncompensated vestibular disorders, purpose of this study is to highlight the vestibular rehabilitation (VR) outcomes in a population of older adults and age-matched mild cognitive impairment (MCI) patients, both affected by unilateral vestibular hypofunction (UVH) and undergoing VR.

Methods

Vestibulo-ocular reflex (VOR), postural sway examination (respectively, performed by video head impulse test and static posturography) and dizziness-related and quality-of-life scores were collected in 12 UVH MCI individuals ≥ 55 years and 12 matched UVH older adults with age-appropriate cognitive function—cognitively evaluated by means of Mini-Mental State Examination (MMSE) and Alzheimer’s Disease Assessment Scale—before and after a VR protocol.

Results

A significant post-treatment reduction in surface, length and power spectra (PS) values within low-frequency domain and an improvement in performance measures were recorded in both groups. Moreover, the VR protocol highlighted—when comparing pre-/post-treatment differences (Δ)—a significant (i) increase in Δ VOR gain; (ii) decrease in Δ surface and length and (iii) increase in Δ PS within low-frequency domain in older adults when compared to MCI patients. Positive correlations were found between MMSE and Δ Dynamic Gait Index, Δ surface and Δ PS within low-frequency domain when treating patients as ‘a continuum’ along the cognitive decline.

Conclusions

Present pilot findings suggest that the cognitive domain insight in older adults scheduled for VR protocols may positively impact on disability consequences.

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Title: Gradient impact of cognitive decline in unilateral vestibular hypofunction after rehabilitation: preliminary findings
Authors: Alessandro Micarelli
Andrea Viziano
Ernesto Bruno
Elisa Micarelli
Ivan Augimeri
Marco Alessandrini
Publication date: 01-10-2018
Publisher: Springer Berlin Heidelberg
Published in: European Archives of Oto-Rhino-Laryngology / Issue 10/2018
Print ISSN: 0937-4477
Electronic ISSN: 1434-4726
DOI: https://doi.org/10.1007/s00405-018-5109-y

At a glance: The STEP trials

Springer Medicine

Gradient impact of cognitive decline in unilateral vestibular hypofunction after rehabilitation: preliminary findings

Abstract

Purpose

Methods

Results

Conclusions

At a glance: The STEP trials

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusions

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