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Published in: Molecular Neurodegeneration 1/2013

Open Access 01-09-2013 | Poster presentation

Glutathion-S-Transferases (GSTs) and Parkinson’s disease in a MPTP-induced C57BL/6 mouse model

Authors: Elcin Deniz Ozdamar, Benay Can-Eke

Published in: Molecular Neurodegeneration | Special Issue 1/2013

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Excerpt

Parkinson’s disease (PD) is the second most common neurodegenerative disorder after Alzheimer disease and affects up to 2% of individuals after the age 65. It is characterized by progressive motor decline and loss of dopaminergic neurons from the substantia nigra (SN) leading resting tremor, rigidity, bradykinesia and postural instability. Differential characteristics of PD pathology is the loss of dopaminergic neurons and the presence of intracellular protein aggregates. The etiology of the disease is still unknown and it is likely due to a multifactorial interaction of genes and the environmental factors on the background of ageing. …
Metadata
Title
Glutathion-S-Transferases (GSTs) and Parkinson’s disease in a MPTP-induced C57BL/6 mouse model
Authors
Elcin Deniz Ozdamar
Benay Can-Eke
Publication date
01-09-2013
Publisher
BioMed Central
Published in
Molecular Neurodegeneration / Issue Special Issue 1/2013
Electronic ISSN: 1750-1326
DOI
https://doi.org/10.1186/1750-1326-8-S1-P30

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