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Acta Neurochirurgica

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Open Access 01-01-2016 | Review Article - Brain Tumors

Glioma surgery in eloquent areas: can we preserve cognition?

Authors: Djaina Satoer, Evy Visch-Brink, Clemens Dirven, Arnaud Vincent

Published in: Acta Neurochirurgica | Issue 1/2016

Abstract

Background

Cognitive preservation is crucial in glioma surgery, as it is an important aspect of daily life functioning. Several studies claimed that surgery in eloquent areas is possible without causing severe cognitive damage. However, this conclusion was relatively ungrounded due to the lack of extensive neuropsychological testing in homogenous patient groups. In this study, we aimed to elucidate the short-term and long-term effects of glioma surgery on cognition by identifying all studies who conducted neuropsychological tests preoperatively and postoperatively in glioma patients.

Methods

We systematically searched the electronical databases Embase, Medline OvidSP, Web of Science, PsychINFO OvidSP, PubMed, Cochrane, Google Scholar, Scirius and Proquest aimed at cognitive performance in glioma patients preoperatively and postoperatively.

Results

We included 17 studies with tests assessing the cognitive domains: language, memory, attention, executive functions and/or visuospatial abilities. Language was the domain most frequently examined. Immediately postoperatively, all studies except one, found deterioration in one or more cognitive domains. In the longer term (3–6/6–12 months postoperatively), the following tests showed both recovery and deterioration compared with the preoperative level: naming and verbal fluency (language), verbal word learning (memory) and Trailmaking B (executive functions).

Conclusions

Cognitive recovery to the preoperative level after surgery is possible to a certain extent; however, the results are too arbitrary to draw definite conclusions and not all studies investigated all cognitive domains. More studies with longer postoperative follow-up with tests for cognitive change are necessary for a better understanding of the conclusive effects of glioma surgery on cognition.

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Title: Glioma surgery in eloquent areas: can we preserve cognition?
Authors: Djaina Satoer
Evy Visch-Brink
Clemens Dirven
Arnaud Vincent
Publication date: 01-01-2016
Publisher: Springer Vienna
Published in: Acta Neurochirurgica / Issue 1/2016
Print ISSN: 0001-6268
Electronic ISSN: 0942-0940
DOI: https://doi.org/10.1007/s00701-015-2601-7

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Glioma surgery in eloquent areas: can we preserve cognition?

Abstract

Background

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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