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01-06-2012 | Baseline Neuropsychological Investigations and Batteries

Measuring clinical outcomes in neuro-oncology. A battery to evaluate low-grade gliomas (LGG)

Authors: Costanza Papagno, Alessandra Casarotti, Alessandro Comi, Marcello Gallucci, Marco Riva, Lorenzo Bello

Published in: Journal of Neuro-Oncology | Issue 2/2012

Abstract

We describe how a neuropsychological evaluation in patients with brain tumors should be performed, specifically in the case of low-grade gliomas. Neuropsychological examination is crucial before starting any treatment as well as during the follow-up, since it can improve neurosurgery techniques and reveal potential cognitive effects of chemotherapy and radiotherapy, besides planning rehabilitation. We underline that sensitive and wide-ranging tests are required; specific tasks based on the lesion site should be added. Moreover, some tests can provide additional information about the evolution of the tumor. A careful, thorough examination improves quality of life.

Bennett TL (2001) Neuropsychological evaluation in rehabilitation planning and evaluation of functional skills. Arch Clin Neuropsychol 16:237–253PubMed

Meyers CA, Hess KR, Yung WKA, Levin VA (2000) Cognitive function as a predictor of survival in patients with recurrent malignant glioma. J Clin Oncol 18:646–650PubMed

Lageman SK, Cerhan JH, Locke DEC, Anderson SK, Wu W, Brown PD (2010) Comparing neuropsychological tasks to optimize brief cognitive batteries for brain tumour clinical trials. J Neuro-Oncol 96:271–276CrossRef

Duffau H, Gatignol P, Moritz-Gasser S, Mandonnet E (2009) Is the left uncinate fasciculus essential for language? A cerebral stimulation study. J Neurol 256:382–389PubMedCrossRef

Damasio H, Grabowsky TJ, Tranel D, Hichwa RD, Damasio AR (1996) A neural basis for lexical retrieval. Nature 380:499–505PubMedCrossRef

Papagno C, Capitani E (1998) Proper name anomia: a case with sparing of the first letter knowledge. Neuropsychologia 36:669–679PubMedCrossRef

Papagno C, Capitani E (2001) Slowly progressive aphasia: a four-year follow-up study. Neuropsychologia 39:678–686PubMedCrossRef

Papagno C, Capasso R, Miceli G (2009) Reversed of concreteness effect for nouns in a subject with semantic dementia. Neuropsychologia 47:1138–1148PubMedCrossRef

Papagno C, Miracapillo C, Casarotti A et al (2011) What is the role of the uncinate fasciculus? Surgical removal and proper name retrieval. Brain 134:405–414PubMedCrossRef

10.

Påhlson A, Ek L, Ahlström G, Smits A (2003) Pitfalls in the assessment of disability in individuals with low-grade gliomas. J Neuro-Oncol 65:149–158CrossRef

11.

Tucha O, Steup A, Smely C, Lange KW (1976) Toe agnosia in Gerstmann syndrome. J Neurol Neurosurg Psychiatry 63:399–403CrossRef

12.

Cohen D, Salanga VD, Hully W, Steinberg MC, Hardy RW (1997) Alexia without agraphia. Neurology 26:455–459CrossRef

13.

Papagno C, Gallucci M, Casarotti A et al (2011) Connectivity constraints on cortical reorganization of neural circuits involved in object naming. Neuroimage 55:1306–1313PubMedCrossRef

14.

Armstrong CL, Goldstein B, Shera D, Ledakis GE, Tallent EM (2003) The predictive value of longitudinal neuropsychologic assessment in the early detection of brain tumor recurrence. Cancer 97:649–656PubMedCrossRef

15.

Capitani E (1997) Normative values and neuropsychological assessment. Common problems in clinical practice and research. Neuropsychol Rehabil 7:295–309CrossRef

16.

Novelli G, Papagno C, Capitani E, Laiacona M, Vallar G, Cappa SF (1986) Tre test clinici di ricerca e produzione lessicale: taratura su soggetti normali. Arch Neurol Psicol Psichiatria 47:477–506

17.

Rizzo S, Venneri A, Papagno C (2002) A normative study of a famous face recognition and naming test. Neurol Sci 23:153–159PubMedCrossRef

18.

Catricalà E, Ginex V, Della Rosa P, Cappa SF (2008) CaGi: a new battery to investigate semantic memory deficits. SIN, Napoli

19.

Parisi D, Pizzamiglio L (1970) Syntactic comprehension in aphasia. Cortex 6:204–215PubMed

20.

De Renzi E, Faglioni P (1978) Normative data and screening power of a shortened version of the token test. Cortex 14:41–49PubMed

21.

Miceli G, Capasso R, Laudanna A, Burani C (1994) Batteria per l’analisi dei deficit afasici. CEPSAG, Roma

22.

Orsini A, Grossi D, Capitani E, Laiacona M, Papagno C, Vallar G (1987) Verbal and spatial immediate memory span: normative data from 1355 adults and 1112 children. Ital J Neurol Sci 8:539–548PubMedCrossRef

23.

Carlesimo GA, Caltagirone C, Gainotti G, Fadda L, Gallassi R, Lorusso S, Marfia G, Marra C, Nocentini U, Parnetti L (1996) The mental deterioration battery: normative data, diagnostic reliability and qualitative analyses of cognitive impairment. Eur Neurol 36:378–384PubMedCrossRef

24.

Capitani E, Laiacona M, Ciceri E, Gruppo Italiano per lo Studio Neuropsicologico dell’Invecchiamento (1991) Sex differences in spatial memory: a reanalysis of block tapping long-term memory according to the short-term memory level. Ital J Neurol Sci 12:461–466

25.

Caffarra P, Vezzadini G, Dieci F, Zonato F, Venneri A (2002) Rey–Osterrieth complex figure: normative values in an Italian population sample. Neurol Sci 22:443–447PubMedCrossRef

26.

Basso A, Capitani E, Laiacona M (1987) Raven’s coloured progressive matrices: normative values on 305 normal adults controls. Funct Neurol 2:189–194PubMed

27.

Spinnler H, Tognoni G (1987) Standardizzazione e taratura italiana di test neuropsicologici [Italian standardization of neuropsychological tests]. Ital J Neurol Sci Suppl 8:1–120

28.

Laiacona M, Inzaghi MG, De Tanti A, Capitani E (2000) Wisconsin card sorting test: a new global score, with Italian norms, and its relationship with the Weigl sorting test. Neurol Sci 21:279–291PubMedCrossRef

29.

Caffarra P, Vezzadini G, Dieci F, Zonato A, Venneri A (2002) Una versione abbreviata del test di Stroop: dati normative nella popolazione italiana. Nuova Riv Neurol 12:111–115

30.

Giovagnoli AR, Del Pesce M, Mascheroni S, Simoncelli M, Laiacona M, Capitani E (1996) Trail making test: normative values from 287 normal adult controls. Ital J Neurol Sci 17:305–309PubMedCrossRef

31.

De Renzi E, Motti F, Nichelli P (1980) Imitating gestures: a quantitative approach to ideomotor apraxia. Arch Neurol 37:6–10PubMedCrossRef

32.

Ronchi R, Posteraro L, Fortis P, Bricolo E, Vallar G (2009) Perseveration in left spatial neglect; drawing and cancellation tasks. Cortex 45:300–312PubMedCrossRef

33.

Bechara A, Damasio AR, Damasio H, Anderson S (1994) Insensitivity to future consequences following damage to human prefrontal cortex. Cognition 50:7–12PubMedCrossRef

34.

Ekman P (1999) Facial expressions. Wiley, Sussex

Title: Measuring clinical outcomes in neuro-oncology. A battery to evaluate low-grade gliomas (LGG)
Authors: Costanza Papagno
Alessandra Casarotti
Alessandro Comi
Marcello Gallucci
Marco Riva
Lorenzo Bello
Publication date: 01-06-2012
Publisher: Springer US
Published in: Journal of Neuro-Oncology / Issue 2/2012
Print ISSN: 0167-594X
Electronic ISSN: 1573-7373
DOI: https://doi.org/10.1007/s11060-012-0824-5

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Measuring clinical outcomes in neuro-oncology. A battery to evaluate low-grade gliomas (LGG)

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