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01-10-2021 | Gingival Diseases | Review Article

Efficacy of antimicrobial photodynamic therapy (aPDT) for nonsurgical treatment of periodontal disease: a systematic review

Authors: Marcella Goetz Moro, Veronica Franco de Carvalho, Bianca A. Godoy-Miranda, Claudio Teruo Kassa, Anna Carolina Ratto Tempestini Horliana, Renato Araujo Prates

Published in: Lasers in Medical Science | Issue 8/2021

Abstract

Although the standard treatment for periodontal disease is based on scaling and root planing (SRP), the use of antimicrobial photodynamic therapy (aPDT) has been studied as a complement to obtain better clinical results. The purpose of this study was to evaluate the effect of aPDT as adjuncts to SRP, compared with SRP alone, on clinical parameters of chronic periodontal patients. Only randomized controlled trials with at least 3-month follow-ups, of SRP alone and in association with aPDT, were included. The MEDLINE (PubMed), Google Scholar, and LILACS databases were searched for articles published up to July 2020. Random-effects meta-analyses were conducted for clinical attachment level (CAL) and probing pocket depth (PPD) change after treatment. Of 141 potentially relevant papers, 22 were included. The association between SRP and aPDT promoted a significant CAL gain and PPD reduction. Periodontal treatment was partially improved by aPDT, and a favorable effect of indocyanine green–mediated aPDT was observed, and high concentrations of phenothiazine chloride presented clinical improvement as well.

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Title: Efficacy of antimicrobial photodynamic therapy (aPDT) for nonsurgical treatment of periodontal disease: a systematic review
Authors: Marcella Goetz Moro
Veronica Franco de Carvalho
Bianca A. Godoy-Miranda
Claudio Teruo Kassa
Anna Carolina Ratto Tempestini Horliana
Renato Araujo Prates
Publication date: 01-10-2021
Publisher: Springer London
Keywords: Gingival Diseases
Diode Laser
Photodynamic Therapy
Periodontal Treatment
Published in: Lasers in Medical Science / Issue 8/2021
Print ISSN: 0268-8921
Electronic ISSN: 1435-604X
DOI: https://doi.org/10.1007/s10103-020-03238-1

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Efficacy of antimicrobial photodynamic therapy (aPDT) for nonsurgical treatment of periodontal disease: a systematic review

Abstract

Keynote webinar | Spotlight on medication adherence

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Abstract

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