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BMC Oral Health
Published in: BMC Oral Health 1/2021

Open Access 01-12-2021 | Gingival Diseases | Research

Oral candidal carriage and its association with dental carious lesions in asymptomatic adults: a cross-sectional study from the UAE

Authors: Suhail H. Al-Amad, Betul Rahman, Nadia Khalifa, Manal A. Awad

Published in: BMC Oral Health | Issue 1/2021

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Abstract

Background

Candida’s potential association with dental caries has previously been reported in children. This research aimed at investigating the associations between Candida species in whole saliva and dental and periodontal health indices in a sample of adult patients.

Methods

A cross-sectional study involving 160 patients investigated the associations between Candida species collected by oral rinse technique, and Decayed, Missing, and Filled Surfaces (DMFS), and periodontal health indices. Chi-square and Independent Samples t-test were used to assess the associations between Candida carriage and confounding variables. Binary logistic regression was used to assess association strengths between Candida carriage and DMFS, adjusted for socio-demographic variables, diabetes mellitus and plaque index.

Results

Candida colonies were identified in 49 (30.6%) patients with CFUs ranging from 103 to 105 colonies per mL. The quantity of Candida CFUs increased with age (r = 0.200; p < 0.05). Among all dental and periodontal health indices, only DMFS was significantly associated with higher values of Candida carriage (p = 0.034), and this association was independent from sex, age, smoking, diabetes mellitus and plaque index (OR: 1.014; 95% CI 1.0–1.03; p = 0.048).

Conclusion

The association between Candida species in whole saliva and DMFS reported here supports an etiological role of Candida in dental cariogenesis among adults.
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Metadata
Title
Oral candidal carriage and its association with dental carious lesions in asymptomatic adults: a cross-sectional study from the UAE
Authors
Suhail H. Al-Amad
Betul Rahman
Nadia Khalifa
Manal A. Awad
Publication date
01-12-2021
Publisher
BioMed Central
Published in
BMC Oral Health / Issue 1/2021
Electronic ISSN: 1472-6831
DOI
https://doi.org/10.1186/s12903-021-01559-3

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