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Irish Journal of Medical Science (1971 -)

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Open Access 01-02-2017 | Review Article

From inflammation to cancer

Authors: A. Korniluk, O. Koper, H. Kemona, V. Dymicka-Piekarska

Published in: Irish Journal of Medical Science (1971 -) | Issue 1/2017

Abstract

Background

The participation of inflammation in the progression of cancer for many years have been the subject of research.

Methods

In the 19th century, there was evidence that an acute inflammation may inhibit the development of cancer. However, chronic inflammation affects the progression of the disease.

Results

Today, it is known that inflammation and cancer use similar mechanisms of development such as severe cell proliferation or angiogenesis. It has been shown that prolonged presence of inflammatory cells and factors in the tumor microenvironment can accelerate its growth and inhibit apoptosis of transformed cells.

Conclusion

In this article we present a brief history of the discovery mechanisms and potential links between acute and chronic inflammation and cancer.

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Title: From inflammation to cancer
Authors: A. Korniluk
O. Koper
H. Kemona
V. Dymicka-Piekarska
Publication date: 01-02-2017
Publisher: Springer London
Published in: Irish Journal of Medical Science (1971 -) / Issue 1/2017
Print ISSN: 0021-1265
Electronic ISSN: 1863-4362
DOI: https://doi.org/10.1007/s11845-016-1464-0

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Abstract

Background

Methods

Results

Conclusion

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