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Published in: Irish Journal of Medical Science (1971 -) 1/2017

01-02-2017 | Original Article

Trial of a novel plasma gas disinfection system (Radica) to reduce mattress residual bacterial contamination in the acute hospital setting: a preliminary study

Authors: F. Shiely, D. Fallon, C. Casey, D. M. Kerins, J. A. Eustace

Published in: Irish Journal of Medical Science (1971 -) | Issue 1/2017

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Abstract

Background

In routine clinical practice, mattresses are manually cleaned using specialised cleaning and high-level disinfecting fluids. While effective against a wide range of organisms, the success of this approach is dependent on a thorough and complete application and is likely to be susceptible to human error and thus variable. The efficacy of available infection control measures to reduce such mattress contamination is unknown as it is not subject to quality control measures. There is a pressing need to identify more effective methods to prevent cross contamination within the medical environment, given the lack of available treatment strategies.

Aim

The purpose of this study is to investigate the ability of a new technology, gaseous technology, to reduce colonization levels, compared to standard cleaning, and so attenuate superficial nosocomial infections.

Methods

We conducted a prospective, single-centre, open-label, non-randomized trial with blinded outcome assessments, comparing the standard cleaning of hospital mattresses with a novel plasma based disinfection system Radica™, followed by a standard post-cleaning culturing protocol (five swabs/mattress).

Results

The median (interquartile range) maximal colony count per mattress for the 20 Radica versus 7 routinely cleaned mattresses was 1 (1–2.7) versus Too-Numerous-to-Count (TNTC) (32-TNTC), respectively, p = 0.002. Of the 20 Radica™ treated mattresses, 12 (60 %) had no positive culture result while all of the standard cleaned mattresses had at least two positive cultures.

Conclusion

The plasma based Radica disinfection system reduces mattress bacterial colonization levels as compared to routine cleaning. This is a potentially important technology in the health care system to reduce surface colonisation and hence nosocomial infections.
Literature
1.
go back to reference Humphreys H, Smyth ETM (2006) Prevalence surveys of healthcare-associated infections: what do they tell us, if anything? Clin Microbiol Infect 12:2–4CrossRefPubMed Humphreys H, Smyth ETM (2006) Prevalence surveys of healthcare-associated infections: what do they tell us, if anything? Clin Microbiol Infect 12:2–4CrossRefPubMed
2.
go back to reference Allegranzi B, Nejad SB, Combescure C, Graafmans W, Attar H, Donaldson L, Pittet D (2011) Burden of endemic health-care-associated infection in developing countries: systematic review and meta-analysis. Lancet. 377:228–241CrossRefPubMed Allegranzi B, Nejad SB, Combescure C, Graafmans W, Attar H, Donaldson L, Pittet D (2011) Burden of endemic health-care-associated infection in developing countries: systematic review and meta-analysis. Lancet. 377:228–241CrossRefPubMed
3.
go back to reference Kilgore ML, Ghosh K, Beavers CM, Wong DY, Hymel PA Jr, Brossettel SE (2008) The costs of nosocomial infections. Medial Care 46:101–104CrossRef Kilgore ML, Ghosh K, Beavers CM, Wong DY, Hymel PA Jr, Brossettel SE (2008) The costs of nosocomial infections. Medial Care 46:101–104CrossRef
4.
go back to reference European Centre for Disease Prevention and Control (2013) Annual epidemiological report on communicable diseases in Europe 2012. European Centre for Disease Pervention and Control, Stockholm European Centre for Disease Prevention and Control (2013) Annual epidemiological report on communicable diseases in Europe 2012. European Centre for Disease Pervention and Control, Stockholm
5.
go back to reference World Health Organisation (2002) Prevention of hospital acquired infections, a practical guide World Health Organisation (2002) Prevention of hospital acquired infections, a practical guide
6.
go back to reference Sanborn WR (1963) The relation of surface contamination to the transmission of disease. Am J Public Health 53(8):1278–1283CrossRef Sanborn WR (1963) The relation of surface contamination to the transmission of disease. Am J Public Health 53(8):1278–1283CrossRef
7.
go back to reference Weber DJ, Rutala WA, Miller MB, Huslage K, Sickbert-Bennett E (2010) Role of hospital surfaces in the transmission of emerging health care-associated pathogens: norovirus, Clostridium difficile, and Acinetobacter species. Am J Infect Control 38 (5 Suppl 1):S25–S33 Weber DJ, Rutala WA, Miller MB, Huslage K, Sickbert-Bennett E (2010) Role of hospital surfaces in the transmission of emerging health care-associated pathogens: norovirus, Clostridium difficile, and Acinetobacter species. Am J Infect Control 38 (5 Suppl 1):S25–S33
8.
go back to reference Creamer E, Humphreys H (2008) The contribution of beds to healthcare-associated infection: the importance of adequate decontamination. J Hosp Infect 69(1):8–23CrossRefPubMed Creamer E, Humphreys H (2008) The contribution of beds to healthcare-associated infection: the importance of adequate decontamination. J Hosp Infect 69(1):8–23CrossRefPubMed
9.
go back to reference Cotter JJ, Maguire P, Soberon F, Daniels S, Ogara JP, Casey E (2011) Disinfection of meticillin-resistant Staphylococcus aureus and Staphylococcus epidermidis biofilms using a remote non-thermal gas plasma. J Hosp Infect 78:204–207CrossRefPubMed Cotter JJ, Maguire P, Soberon F, Daniels S, Ogara JP, Casey E (2011) Disinfection of meticillin-resistant Staphylococcus aureus and Staphylococcus epidermidis biofilms using a remote non-thermal gas plasma. J Hosp Infect 78:204–207CrossRefPubMed
10.
go back to reference O’Connor N, Cahill O, Daniels S, Galvin S, Humphreys H (2014) Cold atmospheric pressure plasma and decontamination. Can it contribute to preventing hosptial-acquired infections? J Hosp Infect 88:59–65CrossRefPubMed O’Connor N, Cahill O, Daniels S, Galvin S, Humphreys H (2014) Cold atmospheric pressure plasma and decontamination. Can it contribute to preventing hosptial-acquired infections? J Hosp Infect 88:59–65CrossRefPubMed
11.
go back to reference Boyce JM (2007) Environmental contamination makes an important contribution to hospital infection. J Hosp Infect 65(Suppl 2):50–54CrossRefPubMed Boyce JM (2007) Environmental contamination makes an important contribution to hospital infection. J Hosp Infect 65(Suppl 2):50–54CrossRefPubMed
Metadata
Title
Trial of a novel plasma gas disinfection system (Radica) to reduce mattress residual bacterial contamination in the acute hospital setting: a preliminary study
Authors
F. Shiely
D. Fallon
C. Casey
D. M. Kerins
J. A. Eustace
Publication date
01-02-2017
Publisher
Springer London
Published in
Irish Journal of Medical Science (1971 -) / Issue 1/2017
Print ISSN: 0021-1265
Electronic ISSN: 1863-4362
DOI
https://doi.org/10.1007/s11845-016-1400-3

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