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Current Osteoporosis Reports
Published in: Current Osteoporosis Reports 4/2018

01-08-2018 | Biomechanics (G Niebur and J Wallace, Section Editors)

Fracture Prediction by Computed Tomography and Finite Element Analysis: Current and Future Perspectives

Authors: Fjola Johannesdottir, Brett Allaire, Mary L. Bouxsein

Published in: Current Osteoporosis Reports | Issue 4/2018

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Abstract

Purpose of Review

This review critiques the ability of CT-based methods to predict incident hip and vertebral fractures.

Recent Findings

CT-based techniques with concurrent calibration all show strong associations with incident hip and vertebral fracture, predicting hip and vertebral fractures as well as, and sometimes better than, dual-energy X-ray absorptiometry areal biomass density (DXA aBMD). There is growing evidence for use of routine CT scans for bone health assessment.

Summary

CT-based techniques provide a robust approach for osteoporosis diagnosis and fracture prediction. It remains to be seen if further technical advances will improve fracture prediction compared to DXA aBMD. Future work should include more standardization in CT analyses, establishment of treatment intervention thresholds, and more studies to determine whether routine CT scans can be efficiently used to expand the number of individuals who undergo evaluation for fracture risk.
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Metadata
Title
Fracture Prediction by Computed Tomography and Finite Element Analysis: Current and Future Perspectives
Authors
Fjola Johannesdottir
Brett Allaire
Mary L. Bouxsein
Publication date
01-08-2018
Publisher
Springer US
Published in
Current Osteoporosis Reports / Issue 4/2018
Print ISSN: 1544-1873
Electronic ISSN: 1544-2241
DOI
https://doi.org/10.1007/s11914-018-0450-z

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