Published in:
01-12-2018 | THE CUTTING EDGE: RESEARCH UPDATE
Fluid intake and chronic kidney disease: effect of coaching an increase in fluid intake on kidney function decline
Authors:
Viviana Bozzano, Elena Abati, Gruppo di Autoformazione Metodologica (GrAM)
Published in:
Internal and Emergency Medicine
|
Issue 8/2018
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Excerpt
Despite the commonly held view that drinking more water is beneficial to kidney function, little scientific data exist that support this belief. In observational studies, increased water intake is associated with a mortality reduction or with a reduced risk of developing chronic kidney disease (CKD) in the general population [
1‐
3]. In animal models of CKD who underwent nearly complete bilateral nephrectomy, it is observed that an increased water consumption suppresses plasmatic antidiuretic hormone (ADH) concentration, reduces levels of copeptin [
4] and improves kidney function [
5]. However, the effects of hyperhydration on kidney function of human patients with CKD have not yet been elucidated. …
