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Endocrine
Published in: Endocrine 1/2017

01-01-2017 | Endocrine Imaging

External ear invasion from an anaplastic thyroid cancer

Authors: Margarida Silva-Vieira, Rita Santos, Valeriano Leite

Published in: Endocrine | Issue 1/2017

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Excerpt

Anaplastic thyroid carcinoma accounts for only 2 % of thyroid carcinomas, but it is one of the most aggressive human malignancies. The majority of patients have extrathyroidal invasion and/or regional lymph node metastases (≈38 %) and/or distant metastases (≈43.0 %). The median survival time is 6 months after the diagnosis and the mortality rate is higher than 90 % [1]. Although multimodality therapies have been used, only patients with distant metastases rarely have responded to traditional therapies, and palliative care is an important component of managing patients with stage IVC disease [2]. …
Literature
1.
E. Kebebew, F.S. Reenspan, O.H. Clark, K.A. Woeber, A. Mcmillan, Treatment outcome and prognostic factors. Cancer 133(7), 1330–1335 (2005)CrossRef
2.
R.C. Smallridge, K.B. Ain, S.L. Asa, K.C. Bible, J.D. Brierley, K.D. Burman et al., American thyroid association guidelines for management of patients with anaplastic thyroid cancer. Thyroid 22(11), 1104–1139 (2012)CrossRefPubMed
Metadata
Title
External ear invasion from an anaplastic thyroid cancer
Authors
Margarida Silva-Vieira
Rita Santos
Valeriano Leite
Publication date
01-01-2017
Publisher
Springer US
Published in
Endocrine / Issue 1/2017
Print ISSN: 1355-008X
Electronic ISSN: 1559-0100
DOI
https://doi.org/10.1007/s12020-016-1114-3

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Keynote webinar | Spotlight on medication adherence

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WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

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