Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

Keynote webinar | Spotlight on medication adherence

LIVE: Thursday 27th June 2024, 18:00-19:30 (CEST)
Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.
ADVANCED SEARCH
Log in
Top
Cardiovascular Toxicology
Published in: Cardiovascular Toxicology 3/2017

01-07-2017

Exposure to Cigarette Smoke and the Carotid Arteries Calcification Index in Patients with Essential Hypertension

Authors: Paweł Gać, Przemysław Jaźwiec, Grzegorz Mazur, Rafał Poręba

Published in: Cardiovascular Toxicology | Issue 3/2017

Login to get access

Abstract

The arteries calcification index is a quantitative, mathematically estimated parameter characterizing the total amount of calcium within atherosclerotic plaques in the walls of arteries. The objective is to determine a relationship between exposure to cigarette smoke and the carotid arteries calcification index in patients with essential hypertension. The tested group included 66 patients with essential hypertension: 19 active smokers (subgroup A), 20 non-smokers, environmentally exposed to cigarette smoke (subgroup B) and 27 persons without exposure to cigarette smoke (subgroup C). The tested group was subjected to computed tomography angiography of carotid arteries. Evaluation of the carotid arteries calcification indexes was conducted. The average value of the total calcification index of the carotid arteries (CAci) amounted to 368.28 ± 384.21. In subgroup A and B in relation to subgroup C, CAci was significantly higher. In summary, active and passive smoking in patients with essential hypertension may be associated with a higher calcification index of carotid arteries.
Literature
1.
World Health Organization. (2015). WHO report on the global tobacco epidemic, 2015. Geneva: WHO.
2.
Perk, J., De Backer, G., Gohlke, H., Graham, I., Reiner, Z., Verschuren, W. M., et al. (2012). European guidelines on cardiovascular disease prevention in clinical practice (version 2012): The fifth joint task force of the European Society of Cardiology and other societies on cardiovascular disease prevention in clinical practice (constituted by representatives of nine societies and by invited experts). International Journal of Behavioral Medicine, 19(4), 403–488.CrossRefPubMed
3.
Gać, P., Poręba, M., Mazur, G., & Poręba, R. (2015). The aortic mechanical properties in patients with the essential hypertension environmentally exposed to cigaret smoke. Inhalation Toxicology, 27(13), 717–723.CrossRefPubMed
4.
Mainali, P., Pant, S., Rodriguez, A. P., Deshmukh, A., & Mehta, J. L. (2015). Tobacco and cardiovascular health. Cardiovascular Toxicology, 15(2), 107–116.CrossRefPubMed
5.
West, H. W., Juonala, M., Gall, S. L., Kähönen, M., Laitinen, T., Taittonen, L., et al. (2015). Exposure to parental smoking in childhood is associated with increased risk of carotid atherosclerotic plaque in adulthood: The cardiovascular risk in Young Finns study. Circulation, 131(14), 1239–1246.CrossRefPubMed
6.
Ibrahimi, P., Jashari, F., Nicoll, R., Bajraktari, G., Wester, P., & Henein, M. Y. (2013). Coronary and carotid atherosclerosis: How useful is the imaging? Atherosclerosis, 231(2), 323–333.CrossRefPubMed
7.
Saba, L., Raz, E., Grassi, R., Di Paolo, P. L., Iacomino, A., Montisci, R., et al. (2013). Association between the volume of carotid artery plaque and its subcomponents and the volume of white matter lesions in patients selected for endarterectomy. AJR. American Journal of Roentgenology, 201(5), W747–W752.CrossRefPubMed
8.
Gać, P., Jaźwiec, P., Mazur, G., Poręba, R. (2015). Exposure to cigarette smoke and the morphology of atherosclerotic plaques in the extracranial arteries assessed by computed tomography angiography in patients with essential hypertension. Cardiovascular Toxicology. Epub ahead of print.
9.
Arjmand Shabestari, A. (2013). Coronary artery calcium score: A review. Iranian Red Crescent Medial Journal, 15(12), e16616.
10.
Agatston, A. S., Janowitz, W. R., Hildner, F. J., Zusmer, N. R., Viamonte, M., Jr., & Detrano, R. (1990). Quantification of coronary artery calcium using ultrafast computed tomography. Journal of the American College of Cardiology, 15(4), 827–832.CrossRefPubMed
11.
Berland, L. L., & Smith, J. K. (1998). Multidetector-array CT: Once again, technology creates new opportunities. Radiology, 209(2), 327–329.CrossRefPubMed
12.
Kwee, R. M. (2010). Systematic review on the association between calcification in carotid plaques and clinical ischemic symptoms. Journal of Vascular Surgery, 51(4), 1015–1025.CrossRefPubMed
13.
Jaźwiec, P., Gać, P., Jurdziak, M., Poręba, M., Mazur, G., Sobieszczańska, M., et al. (2015). Volume of carotid bodies and cardiac autonomic function in patients with essential hypertension. Autonomic Neuroscience, 190, 26–32.CrossRefPubMed
14.
North American Symptomatic Carotid Endarterectomy Trial Collaborators. (1991). Beneficial effect of carotid endarterectomy in symptomatic patients with high-grade carotid stenosis. New England Journal of Medicine, 325(7), 445–453.CrossRef
15.
Cardoso, C. R., Marques, C. E., Leite, N. C., & Salles, G. F. (2012). Factors associated with carotid intima-media thickness and carotid plaques in type 2 diabetic patients. Journal of Hypertension, 30(5), 940–947.CrossRefPubMed
16.
Jiang, C. Q., Xu, L., Lam, T. H., Lin, J. M., Cheng, K. K., & Thomas, G. N. (2010). Smoking cessation and carotid atherosclerosis: the Guangzhou Biobank Cohort Study—CVD. Journal of Epidemiology and Community Health, 64(11), 1004–1009.CrossRefPubMed
17.
Kaźmierski, R., Michalak, S., & Kozubski, W. (2011). Ultrasound-based markers of carotid atherosclerosis correlate well with the number of classical atherosclerotic risk factors. Neurologia i Neurochirurgia Polska, 45(4), 317–327.CrossRefPubMed
18.
Kweon, S. S., Lee, Y. H., Shin, M. H., Choi, J. S., Rhee, J. A., Choi, S. W., et al. (2012). Effects of cumulative smoking exposure and duration of smoking cessation on carotid artery structure. Circulation Journal, 76(8), 2041–2047.CrossRefPubMed
19.
Johnson, H. M., Piper, M. E., Jorenby, D. E., Fiore, M. C., Baker, T. B., & Stein, J. H. (2010). Risk factors for subclinical carotid atherosclerosis among current smokers. Preventive Cardiology, 13(4), 166–171.CrossRefPubMedPubMedCentral
20.
Yerly, P., Rodondi, N., Viswanathan, B., Riesen, W., Vogt, P., & Bovet, P. (2013). Association between conventional risk factors and different ultrasound-based markers of atherosclerosis at carotid and femoral levels in a middle-aged population. International Journal of Cardiovascular Imaging, 29(3), 589–599.CrossRefPubMed
21.
van Gils, M. J., Bodde, M. C., Cremers, L. G., Dippel, D. W., & van der Lugt, A. (2013). Determinants of calcification growth in atherosclerotic carotid arteries; a serial multi-detector CT angiography study. Atherosclerosis, 227(1), 95–99.CrossRefPubMed
22.
Vukadinovic, D., Rozie, S., van Gils, M., van Walsum, T., Manniesing, R., van der Lugt, A., et al. (2012). Automated versus manual segmentation of atherosclerotic carotid plaque volume and components in CTA: Associations with cardiovascular risk factors. International Journal of Cardiovascular Imaging, 28(4), 877–887.CrossRefPubMed
23.
Dores, H., de Araújo Gonçalves, P., Ferreira, A. M., Carvalho, M. S., Sousa, P. J., Cardim, N., et al. (2015). Performance of traditional risk factors in identifying a higher than expected coronary atherosclerotic burden. Revista Portuguesa de Cardiologia, 34(4), 247–253.CrossRefPubMed
24.
Hirooka, N., Kadowaki, T., Sekikawa, A., Ueshima, H., Choo, J., Miura, K., et al. (2013). Influence of cigarette smoking on coronary artery and aortic calcium among random samples from populations of middle-aged Japanese and Korean men. Journal of Epidemiology and Community Health, 67(2), 119–224.CrossRefPubMed
25.
Monti, M., Monti, A., Murdolo, G., Di Renzi, P., Pirro, M. R., Borgognoni, F., et al. (2014). Correlation between epicardial fat and cigarette smoking: CT imaging in patients with metabolic syndrome. Scandinavian Cardiovascular Journal, 48(5), 317–322.CrossRefPubMed
26.
Shaw, L. J., Raggi, P., Callister, T. Q., & Berman, D. S. (2006). Prognostic value of coronary artery calcium screening in asymptomatic smokers and non-smokers. European Heart Journal, 27(8), 968–975.CrossRefPubMed
27.
Szarejko-Paradowska, A., Gluba-Brzózka, A., Pietruszyński, R., Rysz, J. (2015). Assessment of the relationship between selected cardiovascular risk factors and the indices of intima-media thickness and coronary artery calcium score in various stages of chronic kidney disease. International Urology Nephrology. Epub ahead of print.
28.
Mughal, M. M., Khan, M. K., DeMarco, J. K., Majid, A., Shamoun, F., & Abela, G. S. (2011). Symptomatic and asymptomatic carotid artery plaque. Expert Review of Cardiovascular Therapy, 9(10), 1315–1330.CrossRefPubMedPubMedCentral
29.
Kallio, K., Jokinen, E., Saarinen, M., Hämäläinen, M., Volanen, I., Kaitosaari, T., et al. (2010). Arterial intima-media thickness, endothelial function, and apolipoproteins in adolescents frequently exposed to tobacco smoke. Circulation: Cardiovascular Quality and Outcomes, 3(2), 196–203.
30.
Yang, B., Li, M., Chen, B., Xu, Y., & Li, T. D. (2012). Deterioration of endothelial function and carotid intima-media thickness in Tibetan male adolescents exposed to second-hand smoke. Journal of Renin-Angiotensin-Aldosterone System, 13(4), 413–419.CrossRef
Metadata
Title
Exposure to Cigarette Smoke and the Carotid Arteries Calcification Index in Patients with Essential Hypertension
Authors
Paweł Gać
Przemysław Jaźwiec
Grzegorz Mazur
Rafał Poręba
Publication date
01-07-2017
Publisher
Springer US
Published in
Cardiovascular Toxicology / Issue 3/2017
Print ISSN: 1530-7905
Electronic ISSN: 1559-0259
DOI
https://doi.org/10.1007/s12012-016-9391-x

Other articles of this Issue 3/2017

Cardiovascular Toxicology 3/2017 Go to the issue

OriginalPaper

Assessment of Safety Margin of an Antipsychotic Drug Haloperidol for Torsade de Pointes Using the Chronic Atrioventricular Block Dogs

OriginalPaper

Effects of Acute Carbon Monoxide Poisoning on ECG and Echocardiographic Parameters in Children

OriginalPaper

The Myocyte-Damaging Effects of the BCR-ABL1-Targeted Tyrosine Kinase Inhibitors Increase with Potency and Decrease with Specificity

ReviewPaper

Acrolein Can Cause Cardiovascular Disease: A Review

OriginalPaper

H2S Prevents Cyclosporine A-Induced Vasomotor Alteration in Rats

OriginalPaper

Stroke: Temporal Trends and Association with Atmospheric Variables and Air Pollutants in Northern Spain

ACC 2024 Congress Coverage

Year in Review: Heart failure and cardiomyopathies

Heart Failure Video

Watch this official video from ACC.24. Dr. Biykem Bozkurt discusses last year's major advances in heart failure and cardiomyopathies.

Watch now

Semaglutide benefits people with type 2 diabetes and obesity-related heart failure

16-04-2024 Type 2 Diabetes News

Incentivised to exercise

11-04-2024 Lifestyle Modifications News

New intervention for STEMI-related cardiogenic shock

10-04-2024 Myocardial Infarction News

» View more highlights on the ACC 2024 congress hub page

Image Credits