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The Egyptian Journal of Neurology, Psychiatry and Neurosurgery

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Open Access 01-12-2021 | Epilepsy | Research

Hippocampal magnetic resonance imaging in focal onset seizure with impaired awareness—descriptive study from tertiary care centre in southern part of India

Authors: Aleena Elizabeth Andrews, Naufal Perumpalath, Juvaina Puthiyakam, Andrews Mekkattukunnel

Published in: The Egyptian Journal of Neurology, Psychiatry and Neurosurgery | Issue 1/2021

Abstract

Background

Temporal lobe epilepsy is the most common type of focal onset seizure. Focal onset seizure with impaired awareness, previously known as complex partial seizure (CPS), account for 18–40% of all seizure types. Hippocampal sclerosis (HS) is the most common cause of temporal lobe epilepsy, which produces focal onset seizure with impaired awareness. It may be detected in MRI visually, but bilateral abnormalities are better identified using volumetric analysis.

We aimed to compare hippocampal volume in patients with focal onset seizure with impaired awareness visually and quantitatively.

Methodology

This cross-sectional study includes clinically diagnosed cases of 56 focal onset seizure with impaired awareness undergoing MRI at a tertiary teaching hospital in the southern part of India for a duration of 18 months from February 2018 to August 2019.

Results

Out of 53 patients studied using 1.5 T MRI brain with seizure protocols, hippocampal atrophy was identified visually in 13 (24.5%) on the right side, 9 (16.98%) on the left side, and in 6 (11.32%) bilaterally. However, with volumetry, hippocampal atrophy (not taking T2 signal change) was detected in 15 (28.30%) on the right side, 10 (18.86%) on the left side, and in 7 (13.20%) bilaterally. Hippocampal volumes between ipsilateral and contralateral seizure focus were found to have no significant difference (p-0.84).

Conclusions

Though visual analysis is efficient in the diagnosis of pathology, MR volumetry may be used as an expert eye in cases of subtle volume loss.

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Title: Hippocampal magnetic resonance imaging in focal onset seizure with impaired awareness—descriptive study from tertiary care centre in southern part of India
Authors: Aleena Elizabeth Andrews
Naufal Perumpalath
Juvaina Puthiyakam
Andrews Mekkattukunnel
Publication date: 01-12-2021
Publisher: Springer Berlin Heidelberg
Keywords: Epilepsy
Magnetic Resonance Imaging
Magnetic Resonance Imaging
Focal Seizure
Published in: The Egyptian Journal of Neurology, Psychiatry and Neurosurgery / Issue 1/2021
Electronic ISSN: 1687-8329
DOI: https://doi.org/10.1186/s41983-021-00347-8

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Hippocampal magnetic resonance imaging in focal onset seizure with impaired awareness—descriptive study from tertiary care centre in southern part of India

Abstract

Background

Methodology

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methodology

Results

Conclusions

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