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Published in: BMC Gastroenterology 1/2023

Open Access 01-12-2023 | Endoscopic Retrograde Cholangiopancreatography | Research

Enlarged fistulotomy of the papilla as access to the biliary tract during ERCP

Authors: Alexandre Gomes, Ana Sarah Rafka Haidar, Giovani Caetano Padilha, Juliana Bara, Mariana Sussai Nonato, José Mauro da Silva Rodrigues, Pérsio Campos Correia Pinto, Ricardo de Oliveira Ayres, Ronaldo Antonio Borghesi

Published in: BMC Gastroenterology | Issue 1/2023

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Abstract

Background

Demonstration of access to the bile duct through Enlarged Papillary Fistulotomy, a method different from conventional fistulotomy.

Aims

Demonstration of the EFP technique with dissection in layers of the papilla for accessing the common bile duct, its efficiency and safety, rescue of cases of failure in cannulation and cases of access failure by EFP in the first attempt, facilitating cannulation in the second attempt.

Methods

Cross-sectional study, with retrospective data collection from 2233 ERCP exams with 528 EFP procedures, analysis of success and complications.

Results

528 patients underwent EFP on the first attempt, with success in 465 cases (88.06%) and 63 failures (11.94%). Of these failures, 33 patients (52.38%) returned for a second EFP attempt, with success in 30 cases (90.9%) and failure in 3 cases (9.1%). Deep bile duct cannulation was achieved in 93.75% of EFP procedures, and cannulation failure occurred in 33 cases (6.25%).

Conclusion

EFP showed efficiency in CBD cannulation, did not induce post-ERCP pancreatitis, no cases of perforation or false tract, but resulted in higher rates of minor bleeding, rescued cases of access failure by EFP, facilitated the posterior approach on the second attempt, it is safe, effective, low risk and associated with few comorbidities.
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Literature
2.
go back to reference Tse F, Yuan Y, Moayyedi P, Leontiadis GI. Guidewire-assisted cannulation of the common bile duct for the prevention of post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis. Cochrane Database Syst Rev. 2012;12:CD009662.PubMed Tse F, Yuan Y, Moayyedi P, Leontiadis GI. Guidewire-assisted cannulation of the common bile duct for the prevention of post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis. Cochrane Database Syst Rev. 2012;12:CD009662.PubMed
3.
go back to reference Liao WC, Angsuwatcharakon P, Isayama H, Dhir V, Devereaux B, Khor CJ, et al. International consensus recommendations for difficult biliary access. Gastrointest Endosc. 2017;85(2):295–304.CrossRefPubMed Liao WC, Angsuwatcharakon P, Isayama H, Dhir V, Devereaux B, Khor CJ, et al. International consensus recommendations for difficult biliary access. Gastrointest Endosc. 2017;85(2):295–304.CrossRefPubMed
4.
go back to reference Kochar B, Akshintala VS, Afghani E, Elmunzer BJ, Kim KJ, Lennon AM, et al. Incidence, severity, and mortality of post-ERCP pancreatitis: a systematic review by using randomized, controlled trials. Gastrointest Endosc. 2015;81(1):143–9.e9.CrossRefPubMed Kochar B, Akshintala VS, Afghani E, Elmunzer BJ, Kim KJ, Lennon AM, et al. Incidence, severity, and mortality of post-ERCP pancreatitis: a systematic review by using randomized, controlled trials. Gastrointest Endosc. 2015;81(1):143–9.e9.CrossRefPubMed
5.
go back to reference Cennamo V, Fuccio L, Zagari RM, Eusebi LH, Ceroni L, Laterza L, et al. Can a wire-guided cannulation technique increase bile duct cannulation rate and prevent post-ERCP pancreatitis?: a meta-analysis of randomized controlled trials. Am J Gastroenterol. 2009;104(9):2343–50.CrossRefPubMed Cennamo V, Fuccio L, Zagari RM, Eusebi LH, Ceroni L, Laterza L, et al. Can a wire-guided cannulation technique increase bile duct cannulation rate and prevent post-ERCP pancreatitis?: a meta-analysis of randomized controlled trials. Am J Gastroenterol. 2009;104(9):2343–50.CrossRefPubMed
6.
go back to reference Han SY, Baek DH, Kim DU, Park CJ, Park YJ, Lee MW, et al. Primary needle-knife fistulotomy for preventing post-endoscopic retrograde cholangiopancreatography pancreatitis: importance of the endoscopist's expertise level. World J Clin Cases. 2021;9(17):4166–77.CrossRefPubMedPubMedCentral Han SY, Baek DH, Kim DU, Park CJ, Park YJ, Lee MW, et al. Primary needle-knife fistulotomy for preventing post-endoscopic retrograde cholangiopancreatography pancreatitis: importance of the endoscopist's expertise level. World J Clin Cases. 2021;9(17):4166–77.CrossRefPubMedPubMedCentral
7.
8.
go back to reference Kitamura K, Yamamiya A, Ishii Y, Sato Y, Iwata T, Nomoto T, et al. 0.025-inch vs 0.035-inch guide wires for wire-guided cannulation during endoscopic retrograde cholangiopancreatography: a randomized study. World J Gastroenterol. 2015;21(30):9182–8.CrossRefPubMedPubMedCentral Kitamura K, Yamamiya A, Ishii Y, Sato Y, Iwata T, Nomoto T, et al. 0.025-inch vs 0.035-inch guide wires for wire-guided cannulation during endoscopic retrograde cholangiopancreatography: a randomized study. World J Gastroenterol. 2015;21(30):9182–8.CrossRefPubMedPubMedCentral
9.
go back to reference Reddy DN, Nabi Z, Lakhtakia S. How to improve cannulation rates during endoscopic retrograde Cholangiopancreatography. Gastroenterology. 2017;152(6):1275–9.CrossRefPubMed Reddy DN, Nabi Z, Lakhtakia S. How to improve cannulation rates during endoscopic retrograde Cholangiopancreatography. Gastroenterology. 2017;152(6):1275–9.CrossRefPubMed
10.
go back to reference Canena J, Lopes L, Fernandes J, Costa P, Arvanitakis M, Koch AD, et al. Influence of a novel classification of the papilla of Vater on the outcome of needle-knife fistulotomy for biliary cannulation. BMC Gastroenterol. 2021;21(1):147.CrossRefPubMedPubMedCentral Canena J, Lopes L, Fernandes J, Costa P, Arvanitakis M, Koch AD, et al. Influence of a novel classification of the papilla of Vater on the outcome of needle-knife fistulotomy for biliary cannulation. BMC Gastroenterol. 2021;21(1):147.CrossRefPubMedPubMedCentral
11.
go back to reference Sterne JA, Hernán MA, Reeves BC, Savović J, Berkman ND, Viswanathan M, et al. ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions. BMJ. 2016;355:i4919.CrossRefPubMedPubMedCentral Sterne JA, Hernán MA, Reeves BC, Savović J, Berkman ND, Viswanathan M, et al. ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions. BMJ. 2016;355:i4919.CrossRefPubMedPubMedCentral
12.
go back to reference Ayoubi M, Sansoè G, Leone N, Castellino F. Comparison between needle-knife fistulotomy and standard cannulation in ERCP. World J Gastrointest Endosc. 2012;4(9):398–404.CrossRefPubMedPubMedCentral Ayoubi M, Sansoè G, Leone N, Castellino F. Comparison between needle-knife fistulotomy and standard cannulation in ERCP. World J Gastrointest Endosc. 2012;4(9):398–404.CrossRefPubMedPubMedCentral
13.
go back to reference Op den Winkel M, Schirra J, Schulz C, De Toni EN, Steib CJ, Anz D, et al. Biliary cannulation in endoscopic retrograde cholangiography: how to tackle the difficult papilla. Dig Dis. 2022;40(1):85–96.CrossRef Op den Winkel M, Schirra J, Schulz C, De Toni EN, Steib CJ, Anz D, et al. Biliary cannulation in endoscopic retrograde cholangiography: how to tackle the difficult papilla. Dig Dis. 2022;40(1):85–96.CrossRef
14.
go back to reference Testoni PA, Mariani A, Aabakken L, Arvanitakis M, Bories E, Costamagna G, et al. Papillary cannulation and sphincterotomy techniques at ERCP: European Society of Gastrointestinal Endoscopy (ESGE) clinical guideline. Endoscopy. 2016;48(7):657–83.CrossRefPubMed Testoni PA, Mariani A, Aabakken L, Arvanitakis M, Bories E, Costamagna G, et al. Papillary cannulation and sphincterotomy techniques at ERCP: European Society of Gastrointestinal Endoscopy (ESGE) clinical guideline. Endoscopy. 2016;48(7):657–83.CrossRefPubMed
15.
go back to reference Kurita A, Kudo Y, Yoshimura K, Takemura T, Mori Y, Azuma S, et al. Comparison between a rotatable sphincterotome and a conventional sphincterotome for selective bile duct cannulation. Endoscopy. 2019;51(9):852–7.CrossRefPubMed Kurita A, Kudo Y, Yoshimura K, Takemura T, Mori Y, Azuma S, et al. Comparison between a rotatable sphincterotome and a conventional sphincterotome for selective bile duct cannulation. Endoscopy. 2019;51(9):852–7.CrossRefPubMed
16.
go back to reference Sundaralingam P, Masson P, Bourke MJ. Early precut Sphincterotomy does not increase risk during endoscopic retrograde Cholangiopancreatography in patients with difficult biliary access: a Meta-analysis of randomized controlled trials. Clin Gastroenterol Hepatol. 2015;13(10):1722–9.e2.CrossRefPubMed Sundaralingam P, Masson P, Bourke MJ. Early precut Sphincterotomy does not increase risk during endoscopic retrograde Cholangiopancreatography in patients with difficult biliary access: a Meta-analysis of randomized controlled trials. Clin Gastroenterol Hepatol. 2015;13(10):1722–9.e2.CrossRefPubMed
17.
18.
go back to reference Flumignan VK, Seike MG, Souza VS, Cirqueira MI, Silva AB, Artifon ELA. Difficult biliary cannulation: should we always try a second ERCP after a failed needle-knife FISTULOTOMY? Arq Gastroenterol. 2021;58(4):509–13.CrossRefPubMed Flumignan VK, Seike MG, Souza VS, Cirqueira MI, Silva AB, Artifon ELA. Difficult biliary cannulation: should we always try a second ERCP after a failed needle-knife FISTULOTOMY? Arq Gastroenterol. 2021;58(4):509–13.CrossRefPubMed
19.
go back to reference Deng X, Liao R, Pan L, Du C, Wu Q. Second endoscopic retrograde cholangiopancreatography after failure of initial biliary cannulation: a single institution retrospective experience. Exp Ther Med. 2022;23(4):297.CrossRefPubMedPubMedCentral Deng X, Liao R, Pan L, Du C, Wu Q. Second endoscopic retrograde cholangiopancreatography after failure of initial biliary cannulation: a single institution retrospective experience. Exp Ther Med. 2022;23(4):297.CrossRefPubMedPubMedCentral
Metadata
Title
Enlarged fistulotomy of the papilla as access to the biliary tract during ERCP
Authors
Alexandre Gomes
Ana Sarah Rafka Haidar
Giovani Caetano Padilha
Juliana Bara
Mariana Sussai Nonato
José Mauro da Silva Rodrigues
Pérsio Campos Correia Pinto
Ricardo de Oliveira Ayres
Ronaldo Antonio Borghesi
Publication date
01-12-2023
Publisher
BioMed Central
Published in
BMC Gastroenterology / Issue 1/2023
Electronic ISSN: 1471-230X
DOI
https://doi.org/10.1186/s12876-023-03013-w

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