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Journal of Assisted Reproduction and Genetics

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25-01-2024 | Endometriosis | Review

The roles of chromatin regulatory factors in endometriosis

Authors: Liumei Luo, Ling Zhao, Lanyu Cui, Chuyu Peng, Shanshan Ou, Yan Zeng, Bo Liu

Published in: Journal of Assisted Reproduction and Genetics | Issue 4/2024

Abstract

Purpose

Endometriosis is an estrogen-dependent inflammatory disease and one of the most common gynecological diseases in women of reproductive age. The aim of the review was to explore the relationship between the chromatin regulatory factors and endometriosis.

Methods

By searching for literature on chromatin regulators and endometriosis in PuMed. Finally, 98 documents were selected.

Results

Chromatin regulators (CRs) are essential epigenetic regulatory factors that can regulate chromatin structure changes and are usually divided into three categories: DNA methylation compounds, histone modification compounds, and chromatin remodeling complexes. Noncoding RNAs are also chromatin regulators and can form heterochromatin by binding to protein complexes. Chromatin regulators cause abnormal gene expression by regulating chromatin structure, thereby affecting the occurrence and development of endometriosis.

Conclusion

This review summarizes the participation of chromatin regulators in the mechanisms of endometriosis, and these changes in related chromatin regulators provide a comprehensive reference for diagnosis and treatment of endometriosis.

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Title: The roles of chromatin regulatory factors in endometriosis
Authors: Liumei Luo
Ling Zhao
Lanyu Cui
Chuyu Peng
Shanshan Ou
Yan Zeng
Bo Liu
Publication date: 25-01-2024
Publisher: Springer US
Keyword: Endometriosis
Published in: Journal of Assisted Reproduction and Genetics / Issue 4/2024
Print ISSN: 1058-0468
Electronic ISSN: 1573-7330
DOI: https://doi.org/10.1007/s10815-024-03026-8

Keynote webinar | Spotlight on medication adherence

Springer Medicine

The roles of chromatin regulatory factors in endometriosis

Abstract

Purpose

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusion

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