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Published in: Implementation Science 1/2015

Open Access 01-12-2016 | Systematic review

Enablers and barriers to implementing collaborative care for anxiety and depression: a systematic qualitative review

Authors: Gritt Overbeck, Annette Sofie Davidsen, Marius Brostrøm Kousgaard

Published in: Implementation Science | Issue 1/2015

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Abstract

Background

Collaborative care is an increasingly popular approach for improving quality of care for people with mental health problems through an intensified and structured collaboration between primary care providers and health professionals with specialized psychiatric expertise. Trials have shown significant positive effects for patients suffering from depression, but since collaborative care is a complex intervention, it is important to understand the factors which affect its implementation. We present a qualitative systematic review of the enablers and barriers to implementing collaborative care for patients with anxiety and depression.

Methods

We developed a comprehensive search strategy in cooperation with a research librarian and performed a search in five databases (EMBASE, PubMed, PsycINFO, ProQuest, and CINAHL). All authors independently screened titles and abstracts and reviewed full-text articles. Studies were included if they were published in English and based on the original qualitative data on the implementation of a collaborative care intervention targeted at depression or anxiety in an adult patient population in a high-income country. Our subsequent analysis employed the normalization process theory (NPT).

Results

We included 17 studies in our review of which 11 were conducted in the USA, five in the UK, and one in Canada. We identified several barriers and enablers within the four major analytical dimensions of NPT. Securing buy-in among primary care providers was found to be critical but sometimes difficult. Enablers included physician champions, reimbursement for extra work, and feedback on the effectiveness of collaborative care. The social and professional skills of the care managers seemed critical for integrating collaborative care in the primary health care clinic. Day-to-day implementation was also found to be facilitated by the care managers being located in the clinic since this supports regular face-to-face interactions between physicians and care managers.

Conclusions

The following areas require special attention when planning collaborative care interventions: effective educational programs, especially for care managers; issues of reimbursement in relation to primary care providers; good systems for communication and monitoring; and promoting face-to-face interaction between care managers and physicians, preferably through co-location. There is a need for well-sampled, in-depth qualitative studies on the implementation of collaborative care in settings outside the USA and the UK.
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Literature
2.
go back to reference Gunn JM, Palmer VJ, Dowrick CF, Herrman HE, Griffiths FE, Kokanovic R, et al. Embedding effective depression care: using theory for primary care organisational and systems change. Implement Sci. 2010;5:62.CrossRefPubMedPubMedCentral Gunn JM, Palmer VJ, Dowrick CF, Herrman HE, Griffiths FE, Kokanovic R, et al. Embedding effective depression care: using theory for primary care organisational and systems change. Implement Sci. 2010;5:62.CrossRefPubMedPubMedCentral
3.
go back to reference Katon W, Unutzer J, Wells K, Jones L. Collaborative depression care: history, evolution and ways to enhance dissemination and sustainability. Genhosp Psychiatry. 2010;32(5):456–64. Katon W, Unutzer J, Wells K, Jones L. Collaborative depression care: history, evolution and ways to enhance dissemination and sustainability. Genhosp Psychiatry. 2010;32(5):456–64.
4.
go back to reference Bodenheimer T, Wagner EH, Grumbach K. Improving primary care for patients with chronic illness. JAMA. 2002;288(14):1775–9.CrossRefPubMed Bodenheimer T, Wagner EH, Grumbach K. Improving primary care for patients with chronic illness. JAMA. 2002;288(14):1775–9.CrossRefPubMed
5.
go back to reference Thota AB, Sipe TA, Byard GJ, Zometa CS, Hahn RA, McKnight-Eily LR, et al. Collaborative care to improve the management of depressive disorders: a community guide systematic review and meta-analysis. Am J Prev Med. 2012;42(5):525–38.CrossRefPubMed Thota AB, Sipe TA, Byard GJ, Zometa CS, Hahn RA, McKnight-Eily LR, et al. Collaborative care to improve the management of depressive disorders: a community guide systematic review and meta-analysis. Am J Prev Med. 2012;42(5):525–38.CrossRefPubMed
6.
go back to reference Knowles SE, Chew-Graham C, Adeyemi I, Coupe N, Coventry PA. Managing depression in people with multimorbidity: a qualitative evaluation of an integrated collaborative care model. BMC Fam Pract. 2015;16:32.CrossRefPubMedPubMedCentral Knowles SE, Chew-Graham C, Adeyemi I, Coupe N, Coventry PA. Managing depression in people with multimorbidity: a qualitative evaluation of an integrated collaborative care model. BMC Fam Pract. 2015;16:32.CrossRefPubMedPubMedCentral
7.
go back to reference Richards DA, Hill JJ, Gask L, Lovell K, Chew-Graham C, Bower P, et al. Clinical effectiveness of collaborative care for depression in UK primary care (CADET): cluster randomised controlled trial. BMJ. 2013;347:f4913.CrossRefPubMedPubMedCentral Richards DA, Hill JJ, Gask L, Lovell K, Chew-Graham C, Bower P, et al. Clinical effectiveness of collaborative care for depression in UK primary care (CADET): cluster randomised controlled trial. BMJ. 2013;347:f4913.CrossRefPubMedPubMedCentral
8.
go back to reference Coventry P, Lovell K, Dickens C, Bower P, Chew-Graham C, McElvenny D, et al. Integrated primary care for patients with mental and physical multimorbidity: cluster randomised controlled trial of collaborative care for patients with depression comorbid with diabetes or cardiovascular disease. BMJ. 2015;350:h638. Coventry P, Lovell K, Dickens C, Bower P, Chew-Graham C, McElvenny D, et al. Integrated primary care for patients with mental and physical multimorbidity: cluster randomised controlled trial of collaborative care for patients with depression comorbid with diabetes or cardiovascular disease. BMJ. 2015;350:h638.
9.
go back to reference Coupe N, Anderson E, Gask L, Sykes P, Richards DA, Chew-Graham C. Facilitating professional liaison in collaborative care for depression in UK primary care: a qualitative study utilising normalisation process theory. BMC Fam Pract. 2014;15:78.CrossRefPubMedPubMedCentral Coupe N, Anderson E, Gask L, Sykes P, Richards DA, Chew-Graham C. Facilitating professional liaison in collaborative care for depression in UK primary care: a qualitative study utilising normalisation process theory. BMC Fam Pract. 2014;15:78.CrossRefPubMedPubMedCentral
10.
go back to reference Grant MJ, Booth A. A typology of reviews: an analysis of 14 review types and associated methodologies. Health Info Libr J. 2009;26(2):91–108.CrossRefPubMed Grant MJ, Booth A. A typology of reviews: an analysis of 14 review types and associated methodologies. Health Info Libr J. 2009;26(2):91–108.CrossRefPubMed
11.
go back to reference May C, Finch T. Implementing, embedding, and integrating practices: an outline of normalization process theory. Sociology. 2009;43(3):535–54.CrossRef May C, Finch T. Implementing, embedding, and integrating practices: an outline of normalization process theory. Sociology. 2009;43(3):535–54.CrossRef
12.
go back to reference May CR, Mair F, Finch T, MacFarlane A, Dowrick C, Treweek S, et al. Development of a theory of implementation and integration: normalization process theory. Implement Sci. 2009;4:29.CrossRefPubMedPubMedCentral May CR, Mair F, Finch T, MacFarlane A, Dowrick C, Treweek S, et al. Development of a theory of implementation and integration: normalization process theory. Implement Sci. 2009;4:29.CrossRefPubMedPubMedCentral
14.
go back to reference Bamford C, Heaven B, May C, Moynihan P. Implementing nutrition guidelines for older people in residential care homes: a qualitative study using normalization process theory. Implement Sci. 2012;7:106.CrossRefPubMedPubMedCentral Bamford C, Heaven B, May C, Moynihan P. Implementing nutrition guidelines for older people in residential care homes: a qualitative study using normalization process theory. Implement Sci. 2012;7:106.CrossRefPubMedPubMedCentral
15.
go back to reference Bamford C, Poole M, Brittain K, Chew-Graham C, Fox C, Iliffe S, et al. Understanding the challenges to implementing case management for people with dementia in primary care in England: a qualitative study using normalization process theory. BMC Health Serv Res. 2014;14:549. Bamford C, Poole M, Brittain K, Chew-Graham C, Fox C, Iliffe S, et al. Understanding the challenges to implementing case management for people with dementia in primary care in England: a qualitative study using normalization process theory. BMC Health Serv Res. 2014;14:549.
16.
go back to reference Franx G, Oud M, de Lange J, Wensing M, Grol R. Implementing a stepped-care approach in primary care: results of a qualitative study. Implement Sci. 2012;7:8. Franx G, Oud M, de Lange J, Wensing M, Grol R. Implementing a stepped-care approach in primary care: results of a qualitative study. Implement Sci. 2012;7:8.
17.
go back to reference Kennedy A, Rogers A, Chew-Graham C, Blakeman T, Bowen R, Gardner C, et al. Implementation of a self-management support approach (WISE) across a health system: a process evaluation explaining what did and did not work for organisations, clinicians and patients. Implement Sci. 2014;9:129. Kennedy A, Rogers A, Chew-Graham C, Blakeman T, Bowen R, Gardner C, et al. Implementation of a self-management support approach (WISE) across a health system: a process evaluation explaining what did and did not work for organisations, clinicians and patients. Implement Sci. 2014;9:129.
18.
go back to reference Pope C, Halford S, Turnbull J, Prichard J, Calestani M, May C. Using computer decision support systems in NHS emergency and urgent care: ethnographic study using normalisation process theory. BMC Health Serv Res. 2013;13:111. Pope C, Halford S, Turnbull J, Prichard J, Calestani M, May C. Using computer decision support systems in NHS emergency and urgent care: ethnographic study using normalisation process theory. BMC Health Serv Res. 2013;13:111.
19.
go back to reference Gallacher K, Morrison D, Jani B, Macdonald S, May CR, Montori VM, et al. Uncovering treatment burden as a key concept for stroke care: a systematic review of qualitative research. PLoS Med. 2013;10(6):e1001473.CrossRefPubMedPubMedCentral Gallacher K, Morrison D, Jani B, Macdonald S, May CR, Montori VM, et al. Uncovering treatment burden as a key concept for stroke care: a systematic review of qualitative research. PLoS Med. 2013;10(6):e1001473.CrossRefPubMedPubMedCentral
20.
go back to reference Lund S, Richardson A, May C. Barriers to advance care planning at the end of life: an explanatory systematic review of implementation studies. PLoS One. 2015;10(2):e0116629.CrossRefPubMedPubMedCentral Lund S, Richardson A, May C. Barriers to advance care planning at the end of life: an explanatory systematic review of implementation studies. PLoS One. 2015;10(2):e0116629.CrossRefPubMedPubMedCentral
21.
go back to reference Mair FS, May C, O’Donnell C, Finch T, Sullivan F, Murray E. Factors that promote or inhibit the implementation of e-health systems: an explanatory systematic review. Bull World Health Organ. 2012;90(5):357–64.CrossRefPubMedPubMedCentral Mair FS, May C, O’Donnell C, Finch T, Sullivan F, Murray E. Factors that promote or inhibit the implementation of e-health systems: an explanatory systematic review. Bull World Health Organ. 2012;90(5):357–64.CrossRefPubMedPubMedCentral
22.
go back to reference Johnson MJ, May CR. Promoting professional behaviour change in healthcare: what interventions work, and why? A theory-led overview of systematic reviews. BMJ Open. 2015;5(9):e008592.CrossRefPubMedPubMedCentral Johnson MJ, May CR. Promoting professional behaviour change in healthcare: what interventions work, and why? A theory-led overview of systematic reviews. BMJ Open. 2015;5(9):e008592.CrossRefPubMedPubMedCentral
23.
go back to reference Tong A, Flemming K, McInnes E, Oliver S, Craig J. Enhancing transparency in reporting the synthesis of qualitative research: ENTREQ. BMC Med Res Methodol. 2012;12:181.CrossRefPubMedPubMedCentral Tong A, Flemming K, McInnes E, Oliver S, Craig J. Enhancing transparency in reporting the synthesis of qualitative research: ENTREQ. BMC Med Res Methodol. 2012;12:181.CrossRefPubMedPubMedCentral
24.
go back to reference Unützer J HH, Schoenbaum M, Druss B. The collaborative care model: an approach for integrating physical and mental health care in Medicaid health homes. Health Home Information Resource Center, US; 2013. Unützer J HH, Schoenbaum M, Druss B. The collaborative care model: an approach for integrating physical and mental health care in Medicaid health homes. Health Home Information Resource Center, US; 2013.
25.
go back to reference Tong A, Sainsbury P, Craig J. Consolidated criteria for reporting qualitative research (COREQ): a 32-item checklist for interviews and focus groups. Int J Qual Health Care/ISQua. 2007;19(6):349–57.CrossRef Tong A, Sainsbury P, Craig J. Consolidated criteria for reporting qualitative research (COREQ): a 32-item checklist for interviews and focus groups. Int J Qual Health Care/ISQua. 2007;19(6):349–57.CrossRef
26.
go back to reference Anderson K, Stowasser D, Freeman C, Scott I. Prescriber barriers and enablers to minimising potentially inappropriate medications in adults: a systematic review and thematic synthesis. BMJ Open. 2014;4(12):e006544. Anderson K, Stowasser D, Freeman C, Scott I. Prescriber barriers and enablers to minimising potentially inappropriate medications in adults: a systematic review and thematic synthesis. BMJ Open. 2014;4(12):e006544.
27.
go back to reference Prorok JC, Horgan S, Seitz DP. Health care experiences of people with dementia and their caregivers: a meta-ethnographic analysis of qualitative studies. Can Med Assoc J. 2013;185(14):E669–E80.CrossRef Prorok JC, Horgan S, Seitz DP. Health care experiences of people with dementia and their caregivers: a meta-ethnographic analysis of qualitative studies. Can Med Assoc J. 2013;185(14):E669–E80.CrossRef
28.
go back to reference Soundy A, Condon N. Patients experiences of maintaining mental well-being and hope within motor neuron disease: a thematic synthesis. Front Psychol. 2015;6:606. Soundy A, Condon N. Patients experiences of maintaining mental well-being and hope within motor neuron disease: a thematic synthesis. Front Psychol. 2015;6:606.
29.
go back to reference Oishi SM, Shoai R, Katon W, Callahan C, Unutzer J, Inv I. Impacting late life depression: integrating a depression intervention into primary care. Psychiat Quart. 2003;74(1):75–89.CrossRefPubMed Oishi SM, Shoai R, Katon W, Callahan C, Unutzer J, Inv I. Impacting late life depression: integrating a depression intervention into primary care. Psychiat Quart. 2003;74(1):75–89.CrossRefPubMed
30.
go back to reference Nutting PA, Gallagher KM, Riley K, White S, Dietrich AJ, Dickinson WP. Implementing a depression improvement intervention in five health care organizations: experience from the RESPECT-depression trial. Adm Policy Ment Health. 2007;34(2):127–37.CrossRefPubMed Nutting PA, Gallagher KM, Riley K, White S, Dietrich AJ, Dickinson WP. Implementing a depression improvement intervention in five health care organizations: experience from the RESPECT-depression trial. Adm Policy Ment Health. 2007;34(2):127–37.CrossRefPubMed
31.
go back to reference Wozniak L, Soprovich A, Rees S, Al Sayah F, Majumdar SR, Johnson JA. Contextualizing the effectiveness of a collaborative care model for primary care patients with diabetes and depression (teamcare): a qualitative assessment using RE-AIM. Can J Diabetes. 2015;39 Suppl 3:S83–91.CrossRefPubMed Wozniak L, Soprovich A, Rees S, Al Sayah F, Majumdar SR, Johnson JA. Contextualizing the effectiveness of a collaborative care model for primary care patients with diabetes and depression (teamcare): a qualitative assessment using RE-AIM. Can J Diabetes. 2015;39 Suppl 3:S83–91.CrossRefPubMed
32.
go back to reference Curran GM, Sullivan G, Mendel P, Craske MG, Sherbourne CD, Stein MB et al. Implementation of the CALM intervention for anxiety disorders: a qualitative study. Implement Sci. 2012;7:14. Curran GM, Sullivan G, Mendel P, Craske MG, Sherbourne CD, Stein MB et al. Implementation of the CALM intervention for anxiety disorders: a qualitative study. Implement Sci. 2012;7:14.
33.
go back to reference Byng R, Norman I, Redfern S, Jones R. Exposing the key functions of a complex intervention for shared care in mental health: case study of a process evaluation. BMC Health Serv Res. 2008;8:274.CrossRefPubMedPubMedCentral Byng R, Norman I, Redfern S, Jones R. Exposing the key functions of a complex intervention for shared care in mental health: case study of a process evaluation. BMC Health Serv Res. 2008;8:274.CrossRefPubMedPubMedCentral
34.
go back to reference Eghaneyan BH, Sanchez K, Mitschke DB. Implementation of a collaborative care model for the treatment of depression and anxiety in a community health center: results from a qualitative case study. J Multidiscip Health. 2014;7:503–13. Eghaneyan BH, Sanchez K, Mitschke DB. Implementation of a collaborative care model for the treatment of depression and anxiety in a community health center: results from a qualitative case study. J Multidiscip Health. 2014;7:503–13.
35.
go back to reference Sanchez K, Adorno G. “It’s like being a well-loved child”: reflections from a collaborative care team. Prim Care Companion CNS Disorders. 2013;15(6). Sanchez K, Adorno G. “It’s like being a well-loved child”: reflections from a collaborative care team. Prim Care Companion CNS Disorders. 2013;15(6).
36.
go back to reference Huang H, Bauer AM, Wasse JK, Ratzliff A, Chan YF, Harrison D, et al. Care managers’ experiences in a collaborative care program for high risk mothers with depression. Psychosomatics. 2013;54(3):272–6.CrossRefPubMed Huang H, Bauer AM, Wasse JK, Ratzliff A, Chan YF, Harrison D, et al. Care managers’ experiences in a collaborative care program for high risk mothers with depression. Psychosomatics. 2013;54(3):272–6.CrossRefPubMed
37.
go back to reference Knowles SE, Chew-Graham C, Coupe N, Adeyemi I, Keyworth C, Thampy H, et al. Better together? A naturalistic qualitative study of inter-professional working in collaborative care for co-morbid depression and physical health problems. Implement Sci. 2013;8:110.CrossRefPubMedPubMedCentral Knowles SE, Chew-Graham C, Coupe N, Adeyemi I, Keyworth C, Thampy H, et al. Better together? A naturalistic qualitative study of inter-professional working in collaborative care for co-morbid depression and physical health problems. Implement Sci. 2013;8:110.CrossRefPubMedPubMedCentral
38.
go back to reference Nutting PA, Gallagber K, Riley K, White S, Dickinson WP, Korsen N, et al. Care management for depression in primary care practice: findings from the RESPECT-depression trial. Ann Fam Med. 2008;6(1):30–7.CrossRefPubMedPubMedCentral Nutting PA, Gallagber K, Riley K, White S, Dickinson WP, Korsen N, et al. Care management for depression in primary care practice: findings from the RESPECT-depression trial. Ann Fam Med. 2008;6(1):30–7.CrossRefPubMedPubMedCentral
39.
go back to reference Palinkas LA, Ell K, Hansen M, Cabassa L, Wells A. Sustainability of collaborative care interventions in primary care settings. J Soc Work. 2011;11(1):99–117.CrossRef Palinkas LA, Ell K, Hansen M, Cabassa L, Wells A. Sustainability of collaborative care interventions in primary care settings. J Soc Work. 2011;11(1):99–117.CrossRef
40.
go back to reference Whitebird RR, Solberg LI, Jaeckels NA, Pietruszewski PB, Hadzic S, Unutzer J, et al. Effective implementation of collaborative care for depression: what is needed? Am J Manag Care. 2014;20(9):699–707.PubMedPubMedCentral Whitebird RR, Solberg LI, Jaeckels NA, Pietruszewski PB, Hadzic S, Unutzer J, et al. Effective implementation of collaborative care for depression: what is needed? Am J Manag Care. 2014;20(9):699–707.PubMedPubMedCentral
41.
go back to reference Blasinsky M, Goldman HH, Unutzer J. Project IMPACT: a report on barriers and facilitators to sustainability. Admin Pol Ment Health. 2006;33(6):718–29.CrossRef Blasinsky M, Goldman HH, Unutzer J. Project IMPACT: a report on barriers and facilitators to sustainability. Admin Pol Ment Health. 2006;33(6):718–29.CrossRef
42.
go back to reference Gask L, Bower P, Lovell K, Escott D, Archer J, Gilbody S, et al. What work has to be done to implement collaborative care for depression? Process evaluation of a trial utilizing the normalization process model. Implement Sci. 2010;5:15.CrossRefPubMedPubMedCentral Gask L, Bower P, Lovell K, Escott D, Archer J, Gilbody S, et al. What work has to be done to implement collaborative care for depression? Process evaluation of a trial utilizing the normalization process model. Implement Sci. 2010;5:15.CrossRefPubMedPubMedCentral
43.
go back to reference Tai-Seale M, Kunik ME, Shepherd A, Kirchner J, Gottumukkala A. A case study of early experience with implementation of collaborative care in the veterans health administration. Popul Health Manag. 2010;13(6):331–7.CrossRefPubMedPubMedCentral Tai-Seale M, Kunik ME, Shepherd A, Kirchner J, Gottumukkala A. A case study of early experience with implementation of collaborative care in the veterans health administration. Popul Health Manag. 2010;13(6):331–7.CrossRefPubMedPubMedCentral
44.
go back to reference Glasgow RE, Vogt TM, Boles SM. Evaluating the public health impact of health promotion interventions: the RE-AIM framework. Am J Public Realth Res. 1999;89(9):1322–7. Glasgow RE, Vogt TM, Boles SM. Evaluating the public health impact of health promotion interventions: the RE-AIM framework. Am J Public Realth Res. 1999;89(9):1322–7.
45.
go back to reference Glasgow RE, McKay HG, Piette JD, Reynolds KD. The RE-AIM framework for evaluating interventions: what can it tell us about approaches to chronic illness management? Patient Educ Couns. 2001;44(2):119–27.CrossRefPubMed Glasgow RE, McKay HG, Piette JD, Reynolds KD. The RE-AIM framework for evaluating interventions: what can it tell us about approaches to chronic illness management? Patient Educ Couns. 2001;44(2):119–27.CrossRefPubMed
46.
go back to reference McEvoy R, Ballini L, Maltoni S, O’Donnell CA, Mair FS, Macfarlane A. A qualitative systematic review of studies using the normalization process theory to research implementation processes. Implement Sci. 2014;9:2.CrossRefPubMedPubMedCentral McEvoy R, Ballini L, Maltoni S, O’Donnell CA, Mair FS, Macfarlane A. A qualitative systematic review of studies using the normalization process theory to research implementation processes. Implement Sci. 2014;9:2.CrossRefPubMedPubMedCentral
47.
go back to reference Checkland K, Harrison S, Marshall M. Is the metaphor of ‘barriers to change’ useful in understanding implementation? Evidence from general medical practice. J Health Serv Res Policy. 2007;12(2):95–100.CrossRefPubMed Checkland K, Harrison S, Marshall M. Is the metaphor of ‘barriers to change’ useful in understanding implementation? Evidence from general medical practice. J Health Serv Res Policy. 2007;12(2):95–100.CrossRefPubMed
48.
go back to reference Glenton C, Colvin CJ, Carlsen B, Swartz A, Lewin S, Noyes J, et al. Barriers and facilitators to the implementation of lay health worker programmes to improve access to maternal and child health: qualitative evidence synthesis. Cochrane Database Syst Rev. 2013;10:CD010414. Glenton C, Colvin CJ, Carlsen B, Swartz A, Lewin S, Noyes J, et al. Barriers and facilitators to the implementation of lay health worker programmes to improve access to maternal and child health: qualitative evidence synthesis. Cochrane Database Syst Rev. 2013;10:CD010414.
49.
go back to reference Bao YH, Casalino LP, Ettner SL, Bruce ML, Solberg LI, Unutzer J. Designing payment for collaborative care for depression in primary care. Health Serv Res. 2011;46(5):1436–51.CrossRefPubMedPubMedCentral Bao YH, Casalino LP, Ettner SL, Bruce ML, Solberg LI, Unutzer J. Designing payment for collaborative care for depression in primary care. Health Serv Res. 2011;46(5):1436–51.CrossRefPubMedPubMedCentral
Metadata
Title
Enablers and barriers to implementing collaborative care for anxiety and depression: a systematic qualitative review
Authors
Gritt Overbeck
Annette Sofie Davidsen
Marius Brostrøm Kousgaard
Publication date
01-12-2016
Publisher
BioMed Central
Published in
Implementation Science / Issue 1/2015
Electronic ISSN: 1748-5908
DOI
https://doi.org/10.1186/s13012-016-0519-y

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