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Journal of Endocrinological Investigation
Published in: Journal of Endocrinological Investigation 2/2015

01-02-2015 | Comment

Effect of hydrocortisone replacement therapy on body mass index after pituitary surgery

Authors: B. Harbeck, C. S. Haas, H. Mönig

Published in: Journal of Endocrinological Investigation | Issue 2/2015

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Excerpt

Weight gain is a frequent complaint after neurosurgical intervention for pituitary or hypothalamic tumours. This applies in particular to extensive suprasellar operations for excision of hypothalamic tumors or pituitary macroadenomas [1]. We aimed at evaluating the extent to which these patients actually do increase their body mass index (BMI) and to identify a possible relation to pituitary insufficiency, hormone replacement therapy, and quality of life. …
Literature
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Ceccato F, Albiger N, Reimondo G, Frigo AC, Ferasin SF, Occhi G, Mantero F, Terzolo M, Scaroni C (2012) Assessment of glucocorticoid therapy with salivary cortisol in secondary adrenal insufficiency. Eur J Endocrinol 167:769–776. doi:10.​1530/​EJE-12-0534 PubMedCrossRef
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Harbeck B, Kropp P, Mönig H (2009) Effects of short-term nocturnal cortisol replacement on cognitive function and quality of life in patients with primary or secondary adrenal insufficiency: a pilot study. Appl Psychophysiol Biofeedback 34:113–119PubMedCrossRef
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Danilowicz K, Bruno OD, Manavela M, Gomez RM, Barkan A (2008) Correction of cortisol overreplacement ameliorates morbidities in patients with hypopituitarism: a pilot study. Pituitary 11:279–285PubMedCrossRef
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Zueger T, Kirchner P, Herren C, Fischli S, Zwahlen M, Christ E, Stettler C (2012) Glucocorticoid replacement and mortality in patients with nonfunctioning pituitary adenoma. J Clin Endocrinol Metab 97:E1938–E1942. doi:10.​1210/​jc.​2012-2432 PubMedCrossRef
Metadata
Title
Effect of hydrocortisone replacement therapy on body mass index after pituitary surgery
Authors
B. Harbeck
C. S. Haas
H. Mönig
Publication date
01-02-2015
Publisher
Springer International Publishing
Published in
Journal of Endocrinological Investigation / Issue 2/2015
Electronic ISSN: 1720-8386
DOI
https://doi.org/10.1007/s40618-014-0218-y

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