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Head & Face Medicine
Published in: Head & Face Medicine 1/2015

Open Access 01-12-2015 | Research

Does low level laser therapy relieve the pain caused by the placement of the orthodontic separators? ----a meta-analysis

Authors: Quan Shi, Shuo Yang, Fangfang Jia, Juan Xu

Published in: Head & Face Medicine | Issue 1/2015

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Abstract

Objective

Pain caused by orthodontic treatment can affect patient’s compliance and even force them to terminate treatments. The aim of this meta-analysis is to evaluate of the analgesic effect of low level laser therapy (LLLT) after placement of the orthodontic separators.

Methods

Five databases: PubMed, Embase, Cochrane library, China Biology Medicine disc (SinoMed CBM), China National Knowledge Infrastructure (CNKI) were searched for all the appropriate studies in June, 2014. Two reviewers screened the research results under our inclusion criteria and evaluated the risk of bias independently. Then the data of the included studies was extracted for quantitative analysis by the Review Manager 5.1 software.

Results

Six studies were included in our meta-analysis finally. Comparing to the placebo group, the LLLT has good analgesic effect at 6 h, 1d, 2d, 3d after placement of separators which is of statistical significance. While at 2 h, 4d, 5d after the placement, the results tend to support LLLT, but not statistically significant.

Conclusion

Based on current included studies, LLLT can reduce the pain caused by the placement of separators effectively. However, because of the high heterogeneity, well designed RCTs are required in the future.
Literature
1.
Krishnan V. Orthodontic pain: from causes to management--a review. Eur J Orthod. 2007;29(2):170–9.CrossRefPubMed
2.
Bergius M, Kiliaridis S, Berggren U. Pain in orthodontics. A review and discussion of the literature. J Orofac Orthop. 2000;61(2):125–37.CrossRefPubMed
3.
Hoar S, Linnell KJ. Cognitive load eliminates the global perceptual bias for unlimited exposure durations. Atten Percept Psychophys. 2013;75(2):210–5.CrossRefPubMed
4.
Zawawi KH. Acceptance of orthodontic miniscrews as temporary anchorage devices. Patient Prefer Adherence. 2014 Jun 30;8:933–7.
5.
Tortamano A, Lenzi DC, Haddad AC, Bottino MC, Dominguez GC, Vigorito JW. Low-level laser therapy for pain caused by placement of the first orthodontic archwire: a randomized clinical trial. Am J Orthod Dentofacial Orthop. 2009;136(5):662–7.CrossRefPubMed
6.
Youssef M, Ashkar S, Hamade E, Gutknecht N, Lampert F, Mir M. The effect of low-level laser therapy during orthodontic movement: a preliminary study. Lasers Med Sci. 2008;23(1):27–33.CrossRefPubMed
7.
Erdinç AM, Dinçer B. Perception of pain during orthodontic treatment with fixed appliances. Eur J Orthod. 2004;26(1):79–85.CrossRefPubMed
8.
Bondemark L, Fredriksson K, Ilros S. Separation effect and perception of pain and discomfort from two types of orthodontic separators. World J Orthod. 2004;5(2):172–6.PubMed
9.
Polat O, Karaman AI. Pain control during fixed orthodontic appliance therapy. Angle Orthod. 2005;75(2):214–9.PubMed
10.
Xiaoting L, Yin T, Yangxi C. Interventions for pain during fixed orthodontic appliance therapy. A systematic review. Angle Orthod. 2010;80(5):925–32.CrossRefPubMed
11.
Salmassian R, Oesterle LJ, Shellhart WC, Newman SM. Comparison of the efficacy of ibuprofen and acetaminophen in controlling pain after orthodontic tooth movement. Am J Orthod Dentofacial Orthop. 2009;135(4):516–21.CrossRefPubMed
12.
Kyrkanides S, O'Banion MK, Subtelny JD. Nonsteroidal anti-inflammatory drugs in orthodontic tooth movement: metalloproteinase activity and collagen synthesis by endothelial cells. Am J Orthod Dentofacial Orthop. 2000;118(2):203–9.CrossRefPubMed
13.
Nóbrega C, da Silva EM, de Macedo CR. Low-level laser therapy for treatment of pain associated with orthodontic elastomeric separator placement: a placebo-controlled randomized double-blind clinical trial. Photomed Laser Surg. 2013;31(1):10–6.CrossRefPubMed
14.
Kim WT, Bayome M, Park JB, Park JH, Baek SH, Kook YA. Effect of frequent laser irradiation on orthodontic pain. A single-blind randomized clinical trial. Angle Orthod. 2013;83(4):611–6.CrossRefPubMed
15.
Eslamian L, Borzabadi-Farahani A, Hassanzadeh-Azhiri A, Badiee MR, Fekrazad R. The effect of 810-nm low-level laser therapy on pain caused by orthodontic elastomeric separators. Lasers Med Sci. 2014;29(2):559–64.CrossRefPubMed
16.
Artés-Ribas M, Arnabat-Dominguez J, Puigdollers A. Analgesic effect of a low-level laser therapy (830 nm) in early orthodontic treatment. Lasers Med Sci. 2013;28(1):335–41.CrossRefPubMed
17.
Fujiyama K, Deguchi T, Murakami T, Fujii A, Kushima K, Takano-Yamamoto T. Clinical effect of CO2 laser in reducing pain in orthodontics. Angle Orthod. 2008;78(2):299–303.CrossRefPubMed
18.
He WL, Li CJ, Liu ZP, Sun JF, Hu ZA, Yin X, et al. Efficacy of low-level laser therapy in the management of orthodontic pain: a systematic review and meta-analysis. Lasers Med Sci. 2013;28(6):1581–9.CrossRefPubMed
19.
Marini I, Bartolucci ML, Bortolotti F, Innocenti G, Gatto MR, Alessandri Bonetti G. The effect of diode superpulsed low-level laser therapy on experimental orthodontic pain caused by elastomeric separators: a randomized controlled clinical trial. Lasers Med Sci. 2013. [Epub ahead of print]
20.
Zhang HY, Yan Y, Deng HY, Liu HX. Clinical therapeutic evaluation of low-level laser in alleviating pain during orthodontic elastomeric separator placement. Journal of Chinese Practical Diagnosis and Therapy. 2014;28(3):256–8.
21.
Saygun I, Karacay S, Serdar M, Ural AU, Sencimen M, Kurtis B. Effects of laser irradiation on the release of basic fibroblast growth factor (bFGF), insulin like growth factor-1 (IGF-1), and receptor of IGF-1 (IGFBP3) from gingival fibroblasts. Lasers Med Sci. 2008;23(2):211–5.CrossRefPubMed
22.
Pallotta RC, Bjordal JM, Frigo L, Leal Junior EC, Teixeira S, Marcos RL, et al. Infrared (810-nm) low-level laser therapy on rat experimental knee inflammation. Lasers Med Sci. 2012;27(1):71–8.CrossRefPubMed
23.
Pinheiro AL, Gerbi ME. Photoengineering of bone repair processes. Photomed Laser Surg. 2006;24(2):169–78.CrossRefPubMed
24.
Sousa MV, Scanavini MA, Sannomiya EK, Velasco LG, Angelieri F. Influence of low-level laser on the speed of orthodontic movement. Photomed Laser Surg. 2011;29(3):191–6.CrossRefPubMed
25.
Fikácková H, Dostálová T, Navrátil L, Klaschka J. Effectiveness of low-level laser therapy in temporomandibular joint disorders: a placebo-controlled study. Photomed Laser Surg. 2007;25(4):297–303.CrossRefPubMed
26.
Bjordal JM, Johnson MI, Iversen V, Aimbire F, Lopes-Martins RA. Low-level laser therapy in acute pain: a systematic review of possible mechanisms of action and clinical effects in randomized placebo-controlled trials. Photomed Laser Surg. 2006;24(2):158–68.CrossRefPubMed
27.
Higgins JPT, Green S, editors. Cochrane handbook for systematic reviews of interventions [version 5.1.0]. The Cochrane Collaboration. 2011.
28.
Lim HM, Lew KK, Tay DK. A clinical investigation of the efficacy of low level laser therapy in reducing orthodontic postadjustment pain. Am J Orthod Dentofacial Orthop. 1995;108(6):614–22.CrossRefPubMed
29.
Esper MA, Nicolau RA, Arisawa EA. The effect of two phototherapy protocols on pain control in orthodontic procedure--a preliminary clinical study. Lasers Med Sci. 2011;26(5):657–63.CrossRefPubMed
30.
Abtahi SM, Mousavi SA, Shafaee H, Tanbakuchi B. Effect of low-level laser therapy on dental pain induced by separator force in orthodontic treatment. Dent Res J (Isfahan). 2013;10(5):647–51.
Metadata
Title
Does low level laser therapy relieve the pain caused by the placement of the orthodontic separators? ----a meta-analysis
Authors
Quan Shi
Shuo Yang
Fangfang Jia
Juan Xu
Publication date
01-12-2015
Publisher
BioMed Central
Published in
Head & Face Medicine / Issue 1/2015
Electronic ISSN: 1746-160X
DOI
https://doi.org/10.1186/s13005-015-0085-6

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