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Diabetologia

Issue 3/2015

Content (27 Articles)

Open Access In memoriam

Donald F. Steiner, MD, 1930–2014

Kenneth S. Polonsky, Arthur H. Rubenstein

Position Statement

Management of hyperglycaemia in type 2 diabetes, 2015: a patient-centred approach. Update to a Position Statement of the American Diabetes Association and the European Association for the Study of Diabetes

Silvio E. Inzucchi, Richard M. Bergenstal, John B. Buse, Michaela Diamant, Ele Ferrannini, Michael Nauck, Anne L. Peters, Apostolos Tsapas, Richard Wender, David R. Matthews

Review

Epigenetic mechanisms in diabetic complications and metabolic memory

Marpadga A. Reddy, Erli Zhang, Rama Natarajan

Article

The relationship of fibroblast growth factor 21 with cardiovascular outcome events in the Fenofibrate Intervention and Event Lowering in Diabetes study

Kwok-Leung Ong, Andrzej S. Januszewski, Rachel O’Connell, Alicia J. Jenkins, Aimin Xu, David R. Sullivan, Philip J. Barter, Wei-Ting Hung, Russell S. Scott, Marja-Riitta Taskinen, Anthony C. Keech, Kerry-Anne Rye

Open Access Article

Birthweight and risk markers for type 2 diabetes and cardiovascular disease in childhood: the Child Heart and Health Study in England (CHASE)

Claire M. Nightingale, Alicja R. Rudnicka, Christopher G. Owen, Sian L. Newton, Jennifer L. Bales, Angela S. Donin, Cathy M. McKay, Phillip J. Steer, Debbie A. Lawlor, Naveed Sattar, Derek G. Cook, Peter H. Whincup

Article

Dose–response relationships between sedentary behaviour and the metabolic syndrome and its components

Keith P. Gennuso, Ronald E. Gangnon, Keith M. Thraen-Borowski, Lisa H. Colbert

Article

Pioglitazone and bladder cancer risk: a multipopulation pooled, cumulative exposure analysis

Daniel Levin, Samira Bell, Reijo Sund, Sirpa A. Hartikainen, Jaakko Tuomilehto, Eero Pukkala, Ilmo Keskimäki, Ellena Badrick, Andrew G. Renehan, Iain E. Buchan, Samantha L. Bowker, Jasjeet K. Minhas-Sandhu, Zafar Zafari, Carlo Marra, Jeffrey A. Johnson, Bruno H. Stricker, Andrè G. Uitterlinden, Albert Hofman, Rikje Ruiter, Catherine E. de Keyser, Thomas M. MacDonald, Sarah H. Wild, Paul M. McKeigue, Helen M. Colhoun

Article

Glucose, blood pressure and cholesterol levels and their relationships to clinical outcomes in type 2 diabetes: a retrospective cohort study

Evangelos Kontopantelis, David A. Springate, David Reeves, Darren M. Ashcroft, Martin Rutter, Iain Buchan, Tim Doran

Short Communication

ABO and Rhesus blood groups and risk of type 2 diabetes: evidence from the large E3N cohort study

Guy Fagherazzi, Gaëlle Gusto, Françoise Clavel-Chapelon, Beverley Balkau, Fabrice Bonnet

Article

Fasting serum levels of ferritin are associated with impaired pancreatic beta cell function and decreased insulin sensitivity: a population-based study

Linéa Bonfils, Christina Ellervik, Nele Friedrich, Allan Linneberg, Camilla H. Sandholt, Marit E. Jørgensen, Torben Jørgensen, Torben Hansen, Oluf Pedersen, Kristine H. Allin

Open Access Article

Age trajectories of glycaemic traits in non-diabetic South Asian and white individuals: the Whitehall II cohort study

Satoyo Ikehara, Adam G. Tabák, Tasnime N. Akbaraly, Adam Hulmán, Mika Kivimäki, Nita G. Forouhi, Hiroyasu Iso, Eric J. Brunner

Short Communication

SORBS1 gene, a new candidate for diabetic nephropathy: results from a multi-stage genome-wide association study in patients with type 1 diabetes

Marine Germain, Marcus G. Pezzolesi, Niina Sandholm, Amy J. McKnight, Katalin Susztak, Maria Lajer, Carol Forsblom, Michel Marre, Hans-Henrik Parving, Peter Rossing, Iiro Toppila, Jan Skupien, Ronan Roussel, Yi-An Ko, Nora Ledo, Lasse Folkersen, Mete Civelek, Alexander P. Maxwell, David-Alexandre Tregouet, Per-Henrik Groop, Lise Tarnow, Samy Hadjadj

Article

Selective inhibition of 12-lipoxygenase protects islets and beta cells from inflammatory cytokine-mediated beta cell dysfunction

David A. Taylor-Fishwick, Jessica Weaver, Lindsey Glenn, Norine Kuhn, Ganesha Rai, Ajit Jadhav, Anton Simeonov, Angela Dudda, Dieter Schmoll, Theodore R. Holman, David J. Maloney, Jerry L. Nadler

Open Access Article

Ins1 Cre knock-in mice for beta cell-specific gene recombination

Bernard Thorens, David Tarussio, Miguel Angel Maestro, Meritxell Rovira, Eija Heikkilä, Jorge Ferrer

Article

MafA is critical for maintenance of the mature beta cell phenotype in mice

Wataru Nishimura, Satoru Takahashi, Kazuki Yasuda

Article

IL-1 mediates amyloid-associated islet dysfunction and inflammation in human islet amyloid polypeptide transgenic mice

Clara Y. Westwell-Roper, Cyrus A. Chehroudi, Heather C. Denroche, Jaques A. Courtade, Jan A. Ehses, C. Bruce Verchere

Article

Glucose uptake in human brown adipose tissue is impaired upon fasting-induced insulin resistance

Mark J. W. Hanssen, Roel Wierts, Joris Hoeks, Anne Gemmink, Boudewijn Brans, Felix M. Mottaghy, Patrick Schrauwen, Wouter D. van Marken Lichtenbelt

Article

Increased gluconeogenesis in youth with newly diagnosed type 2 diabetes

Stephanie T. Chung, Daniel S. Hsia, Shaji K. Chacko, Luisa M. Rodriguez, Morey W. Haymond

Open Access Article

GLP-1–oestrogen attenuates hyperphagia and protects from beta cell failure in diabetes-prone New Zealand obese (NZO) mice

Robert W. Schwenk, Christian Baumeier, Brian Finan, Oliver Kluth, Christine Brauer, Hans-Georg Joost, Richard D. DiMarchi, Matthias H. Tschöp, Annette Schürmann

Article

Pre-gestational vs gestational exposure to maternal obesity differentially programs the offspring in mice

Isaac E. Sasson, Alexa P. Vitins, Monica A. Mainigi, Kelle H. Moley, Rebecca A. Simmons

Article

Diabetes reduces mesenchymal stem cells in fracture healing through a TNFα-mediated mechanism

Kang I. Ko, Leila S. Coimbra, Chen Tian, Jazia Alblowi, Rayyan A. Kayal, Thomas A. Einhorn, Louis C. Gerstenfeld, Robert J. Pignolo, Dana T. Graves

Erratum

Erratum to: Modulation of p75NTR prevents diabetes- and proNGF-induced retinal inflammation and blood–retina barrier breakdown in mice and rats

Barbara A. Mysona, Mohammed M. H. Al-Gayyar, Suraporn Matragoon, Mohammed A. Abdelsaid, Mona F. El-Azab, H. Uri Saragovi, Azza B. El-Remessy

Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin
Prof. Florian Limbourg
Prof. Anoop Chauhan
Developed by: Springer Medicine
Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Highlights from the ACC 2024 Congress

Year in Review: Pediatric cardiology

Watch Dr. Anne Marie Valente present the last year's highlights in pediatric and congenital heart disease in the official ACC.24 Year in Review session.

Year in Review: Pulmonary vascular disease

The last year's highlights in pulmonary vascular disease are presented by Dr. Jane Leopold in this official video from ACC.24.

Year in Review: Valvular heart disease

Watch Prof. William Zoghbi present the last year's highlights in valvular heart disease from the official ACC.24 Year in Review session.

Year in Review: Heart failure and cardiomyopathies

Watch this official video from ACC.24. Dr. Biykem Bozkurt discusses last year's major advances in heart failure and cardiomyopathies.