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Archives of Virology
Published in: Archives of Virology 10/2016

01-10-2016 | Brief Report

Detection and genetic characterization of hepatitis E virus (HEV) genotype 3 subtype c in wild boars in Italy

Authors: Federica Di Profio, Irene Melegari, Vittorio Sarchese, Serena Robetto, Giuseppe Marruchella, Maria Cristina Bona, Riccardo Orusa, Vito Martella, Fulvio Marsilio, Barbara Di Martino

Published in: Archives of Virology | Issue 10/2016

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Abstract

Hepatitis E virus (HEV) was detected in stools collected from wild boars in Italy, with an overall prevalence of 1.5 % (3/196). The sequence of a ~3.0-kb portion at the 3′ end of the genome of one such strain, HEV/WB/P6-15/ITA, was determined. In the full-length ORF2, which encodes the capsid protein, the virus was genetically closest to wild boar and human HEV strains currently classified as genotype 3 subtype c. Interestingly, the 3’ end of ORF2 of the WB/P6-15/ITA matched the 340-nucleotide (nt) sequence (94.0 % nt identity) of the human strain PeGe, identified in 2015 from a patient with acute hepatitis E in Genoa, Italy, suggesting that similar HEV strains are circulating in the same geographical setting in humans and animals.
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Metadata
Title
Detection and genetic characterization of hepatitis E virus (HEV) genotype 3 subtype c in wild boars in Italy
Authors
Federica Di Profio
Irene Melegari
Vittorio Sarchese
Serena Robetto
Giuseppe Marruchella
Maria Cristina Bona
Riccardo Orusa
Vito Martella
Fulvio Marsilio
Barbara Di Martino
Publication date
01-10-2016
Publisher
Springer Vienna
Published in
Archives of Virology / Issue 10/2016
Print ISSN: 0304-8608
Electronic ISSN: 1432-8798
DOI
https://doi.org/10.1007/s00705-016-2964-y

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