De Novo Inflammatory Bowel Disease After Bariatric Surgery: A Case Series and Literature Review

Excerpt

Paralleling the alarming rise in rates of obesity and obesity-related comorbid conditions in the USA, the number of bariatric surgeries continues to increase in recent years, according to the American Society for Metabolic and Bariatric Surgery. Roux-en-Y gastric bypass (RYGB) is one of the most commonly performed bariatric surgeries in the USA. The two main mechanisms for weight loss with RYGB involve a combination of food restriction and bypass of absorptive and secretory components of the digestive tract. While the aforementioned mechanisms are effective in both induction and maintenance of sustained weight loss, unfortunately, they can lead to various complications as well. Such complications may be predominantly nutritional (micronutrient and macronutrient deficiencies, dehydration) or gastrointestinal (diarrhea, nausea, vomiting, abdominal pain, ulcers, strictures, gallstones, hernias) in nature [1]. To date, there have been only seven reported cases in the literature of new onset Crohn’s disease (CD) after gastrointestinal bypass surgery [1‐4]. We present two cases of new onset CD after RYGB. …