Published in:
01-10-2006 | Case Report
De Novo Hepatocellular Carcinoma Occurring in a Transplanted Liver: Case Report and Review of the Literature
Authors:
Anca Croitoru, Thomas D. Schiano, Myron Schwartz, Sasan Roayaie, Ruliang Xu, Arief Suriawinata, M. Isabel Fiel
Published in:
Digestive Diseases and Sciences
|
Issue 10/2006
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Excerpt
One of the main indications for liver transplantation in patients with end-stage liver disease is hepatitis C virus (HCV)-induced cirrhosis [
1,
2]. Cirrhosis from any cause may give rise to hepatocellular carcinoma (HCC). Recurrence of HCV infection in the liver allograft is almost universal and may lead to graft failure and/or cirrhosis in between 10 and 30% of cases within 5 years [
3‐
5]. Only two cases have been previously reported in the medical literature in which HCC developed in the liver allograft in the setting of recurrent HCV and cirrhosis [
6,
7]. We report an additional case of de novo HCC in a cirrhotic allograft with recurrent hepatitis C. …
