Published in:
01-03-2020 | Cytostatic Therapy | Case Report
Hepatoblastoma in a Young Adult: a Rare Case Report and Review of the Literature
Authors:
Jeewan Ram Vishnoi, Ajai Sasidhar, Sanjeev Misra, Puneet Pareek, Sudeep Khera, Sushil Kumar, Ankit Jain
Published in:
Journal of Gastrointestinal Cancer
|
Issue 1/2020
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Excerpt
Hepatoblastoma is the most common primary liver malignant neoplasm occurring under the age of 2 years. Hepatoblastoma is considered to arise during the embryogenesis; it is derived from pluripotent hepatic stem cells [
1]. The pathogenesis is related to deranged liver organogenesis, and often the tumor recapitulates the stages of liver development [
2]. Therefore, approximately 90% of the cases occur under the age of 5 years [
3], and the median age of presentation is between 16 and 18 months. The occurrences of the hepatoblastoma in the young adult or middle age are extremely rare and have a poor prognosis. A 2016 extensive literature review by Celotti et al. [
4], which analyzed all the cases of hepatoblastoma in adults reported in English, as well as other languages, found only 63 cases including only two case reports from India [
5]. Here, we report a case of hepatoblastoma in an 18-year-old girl to highlight the atypical age and presentation of the disease. …
