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Current Nutrition Reports
Published in: Current Nutrition Reports 3/2020

01-09-2020 | Cystic Fibrosis | Functional Foods (CM Whisner, Section Editor)

Soy Isoflavones and Gastrointestinal Health

Authors: Layla Al-Nakkash, Aaron Kubinski

Published in: Current Nutrition Reports | Issue 3/2020

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Abstract

Purpose of Review

Soy isoflavones are known to have beneficial effects on several aspects of gastrointestinal physiological functions (contractility or motility, secretion, morphology, and barrier function). In this review, we discuss the effects of soy isoflavones on the overall gut function and inflammation and assess how these effects might be implicated in the treatment of several gut-related diseases.

Recent Findings

Soy isoflavones influence several key aspects of gastrointestinal health: improve basal intestinal secretion, alleviate inflammation, limit intestinal morphological damage, and improve epithelial barrier function in several clinically relevant murine models of gastrointestinal diseases.

Summary

Dietary supplementation with isoflavones proves to be a key means to improve the overall gut function and health. Future mechanistic studies with isoflavone interventions will help treat clinically related diseases such as cystic fibrosis and inflammatory-related gut problems such as colitis and diabetes.
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Metadata
Title
Soy Isoflavones and Gastrointestinal Health
Authors
Layla Al-Nakkash
Aaron Kubinski
Publication date
01-09-2020
Publisher
Springer US
Published in
Current Nutrition Reports / Issue 3/2020
Electronic ISSN: 2161-3311
DOI
https://doi.org/10.1007/s13668-020-00314-4

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