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World Journal of Surgical Oncology
Published in: World Journal of Surgical Oncology 1/2023

Open Access 01-12-2023 | Cutaneous Squamous Cell Carcinoma | Case Report

Successful management of in-transit cutaneous squamous cell carcinoma with anti-PD-1 immunotherapy

Authors: Chris Furkert, Richard Martin, Avinash Sharma, Gareth Rivalland

Published in: World Journal of Surgical Oncology | Issue 1/2023

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Abstract

This report describes the case of a 70-year-old man with metastatic squamous cell carcinoma (SCC) of the right lower leg. Soon after definitive surgical management of the primary and nodal metastases with curative intent, he relapsed, developing aggressive in-transit metastatic disease and recurrent nodal disease. The patient was treated with systemic immunotherapy alone, which not only prompted the progressive nodal metastases to regress, but also resulted in a complete response of the in-transit disease. This situation is previously undescribed in the medical literature.
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Metadata
Title
Successful management of in-transit cutaneous squamous cell carcinoma with anti-PD-1 immunotherapy
Authors
Chris Furkert
Richard Martin
Avinash Sharma
Gareth Rivalland
Publication date
01-12-2023
Publisher
BioMed Central
Published in
World Journal of Surgical Oncology / Issue 1/2023
Electronic ISSN: 1477-7819
DOI
https://doi.org/10.1186/s12957-023-03179-3

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