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Published in: Pediatric Radiology 9/2005

01-09-2005 | Technical Innovation

CT-guided radiofrequency ablation of pediatric Wilms tumor in a solitary kidney

Authors: Stephen D. Brown, Eric vanSonnenberg, Paul R. Morrison, Lisa Diller, Robert C. Shamberger

Published in: Pediatric Radiology | Issue 9/2005

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Abstract

Although recent results of percutaneous imaging-guided radiofrequency ablation (RFA) of various tumors in adults are promising, RFA of tumors in children has been performed in only a small number of cases. We describe the treatment of Wilms tumor in a solitary kidney in a 5-year-old girl using percutaneous CT-guided RFA. The procedure provided short-term palliation in this child for whom partial or total nephrectomy carried high risk and low likelihood of success. Although it might only be useful ultimately as a temporizing measure, oncologists and surgeons might wish to consider RFA in children who would otherwise require dialysis and renal transplantation or who are poor surgical candidates. Various specific technical issues differentiate pediatric from adult tumor ablation, including the amount of intra-abdominal fat, need for smaller grounding pads, and potential systemic effects of tissue heating.
Literature
1.
go back to reference Wood BJ, Ramkaransingh JR, Fojo T, et al (2002) Percutaneous tumor ablation with radiofrequency. Cancer 94:443–451 Wood BJ, Ramkaransingh JR, Fojo T, et al (2002) Percutaneous tumor ablation with radiofrequency. Cancer 94:443–451
2.
go back to reference Shiels WE, Brown SD (2005) Radiofrequency tumor ablation in children. In: vanSonnenberg E, McMullen W, Solbiati L (eds) Tumor ablation: principles and practice. Springer, New York Shiels WE, Brown SD (2005) Radiofrequency tumor ablation in children. In: vanSonnenberg E, McMullen W, Solbiati L (eds) Tumor ablation: principles and practice. Springer, New York
4.
go back to reference Gervais DA, McGovern FJ, Arellano RS, et al (2003) Renal cell carcinoma: clinical experience and technical success with radio-frequency ablation of 42 tumors. Radiology 226:417–424 Gervais DA, McGovern FJ, Arellano RS, et al (2003) Renal cell carcinoma: clinical experience and technical success with radio-frequency ablation of 42 tumors. Radiology 226:417–424
5.
go back to reference Mahnken AH, Gunther RW, Tacke J (2004) Radiofrequency ablation of renal tumors. Eur Radiol 14:1449–1455 Mahnken AH, Gunther RW, Tacke J (2004) Radiofrequency ablation of renal tumors. Eur Radiol 14:1449–1455
6.
go back to reference Farrell MA, Charboneau JW, Callstrom MR, et al (2003) Paranephric water instillation: a technique to prevent bowel injury during percutaneous renal radiofrequency ablation. AJR 181:1315–1317PubMed Farrell MA, Charboneau JW, Callstrom MR, et al (2003) Paranephric water instillation: a technique to prevent bowel injury during percutaneous renal radiofrequency ablation. AJR 181:1315–1317PubMed
7.
go back to reference Pavlovich CP, Walther MM, Choyke PL, et al (2002) Percutaneous radio frequency ablation of small renal tumors: initial results. J Urol 167:10–15CrossRefPubMed Pavlovich CP, Walther MM, Choyke PL, et al (2002) Percutaneous radio frequency ablation of small renal tumors: initial results. J Urol 167:10–15CrossRefPubMed
8.
go back to reference Kam AW, Littrup PJ, Walther MM, et al (2004) Thermal protection during percutaneous thermal ablation of renal cell carcinoma. J Vasc Interv Radiol 15:753–758PubMed Kam AW, Littrup PJ, Walther MM, et al (2004) Thermal protection during percutaneous thermal ablation of renal cell carcinoma. J Vasc Interv Radiol 15:753–758PubMed
9.
go back to reference Schultze D, Morris CS, Bhave AD, et al (2003) Radiofrequency ablation of renal transitional cell carcinoma with protective cold saline infusion. J Vasc Interv Radiol 14:489–492PubMed Schultze D, Morris CS, Bhave AD, et al (2003) Radiofrequency ablation of renal transitional cell carcinoma with protective cold saline infusion. J Vasc Interv Radiol 14:489–492PubMed
10.
go back to reference Polderman KH (2004) Application of therapeutic hypothermia in the intensive care unit. Opportunities and pitfalls of a promising treatment modality. 2. Practical aspects and side effects. Intensive Care Med 30:757–769CrossRefPubMed Polderman KH (2004) Application of therapeutic hypothermia in the intensive care unit. Opportunities and pitfalls of a promising treatment modality. 2. Practical aspects and side effects. Intensive Care Med 30:757–769CrossRefPubMed
11.
go back to reference Beckwith JB (1993) Precursor lesions of Wilms tumor: clinical and biological implications. Med Pediatr Oncol 21:158–168PubMed Beckwith JB (1993) Precursor lesions of Wilms tumor: clinical and biological implications. Med Pediatr Oncol 21:158–168PubMed
Metadata
Title
CT-guided radiofrequency ablation of pediatric Wilms tumor in a solitary kidney
Authors
Stephen D. Brown
Eric vanSonnenberg
Paul R. Morrison
Lisa Diller
Robert C. Shamberger
Publication date
01-09-2005
Publisher
Springer-Verlag
Published in
Pediatric Radiology / Issue 9/2005
Print ISSN: 0301-0449
Electronic ISSN: 1432-1998
DOI
https://doi.org/10.1007/s00247-005-1510-y

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