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01-12-2021 | Crohn's Disease | Original Article

Short-term outcomes and healthcare resource utilization following incisional hernia repair with synthetic mesh in patients with Crohn’s disease

Authors: B. C. Perlmutter, H. Alkhatib, A. L. Lightner, A. Fafaj, S. J. Zolin, C. C. Petro, D. M. Krpata, A. S. Prabhu, S. D. Holubar, M. J. Rosen

Published in: Hernia | Issue 6/2021

Abstract

Purpose

While the use of synthetic mesh for incisional hernia repair reduces recurrence rates, little evidence exists regarding the impact of this practice on the disease burden of a Crohn’s patient. We aimed to describe the post-operative outcomes and healthcare resource utilization following incisional hernia repair with synthetic mesh in patients with Crohn’s disease.

Methods

A retrospective review of adult patients with Crohn’s disease who underwent elective open incisional hernia repair with extra-peritoneal synthetic mesh from 2014 to 2018 at a single large academic hospital with surgeons specializing in hernia repair was conducted. Primary outcomes included 30-day post-operative complications and long-term rates of fistula formation and hernia recurrence. The secondary outcome compared healthcare resource utilization during a standardized fourteen-month period before and after hernia repair.

Results

Among the 40 patients included, six (15%) required readmission, 4 (10%) developed a surgical site occurrence, 3 (7.5%) developed a surgical site infection, and one (2.5%) required reoperation within the first 30 days. The overall median follow-up time was 42 months (IQR = 33–56), during which time one (2.5%) patient developed an enterocutaneous fistula and eight (20%) experienced hernia recurrence. Healthcare resource utilization remained unchanged or decreased across every category following repair.

Conclusion

The use of extra-peritoneal synthetic mesh during incisional hernia repair in patients with Crohn’s disease was not associated with a prohibitively high rate of post-operative complications or an increase in healthcare resource utilization to suggest worsening disease during the first 4 years after repair. Future studies exploring the long-term outcomes of this technique are needed.

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Title: Short-term outcomes and healthcare resource utilization following incisional hernia repair with synthetic mesh in patients with Crohn’s disease
Authors: B. C. Perlmutter
H. Alkhatib
A. L. Lightner
A. Fafaj
S. J. Zolin
C. C. Petro
D. M. Krpata
A. S. Prabhu
S. D. Holubar
M. J. Rosen
Publication date: 01-12-2021
Publisher: Springer Paris
Keywords: Crohn's Disease
Incisional Hernia
Published in: Hernia / Issue 6/2021
Print ISSN: 1265-4906
Electronic ISSN: 1248-9204
DOI: https://doi.org/10.1007/s10029-021-02476-8

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Short-term outcomes and healthcare resource utilization following incisional hernia repair with synthetic mesh in patients with Crohn’s disease

Abstract

Purpose

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusion

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