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01-12-2021 | Wound Dehiscence | Review

Prophylactic negative pressure wound therapy after open ventral hernia repair: a systematic review and meta-analysis

Authors: V. Berner-Hansen, E. Oma, M. Willaume, K. K. Jensen

Published in: Hernia | Issue 6/2021

Abstract

Purpose

Negative pressure wound therapy on closed incisions (iNPWT) is a wound dressing system developed to promote wound healing and avoid complications after surgical procedures. The effect of iNPWT is well established in various surgical fields, however, the effect on postoperative wound complications after ventral hernia repair remains unknown. The aim of this systematic review and meta-analysis was to investigate the effect of iNPWT on patients undergoing open ventral hernia repair (VHR) compared with conventional wound dressing.

Materials and methods

This systematic review and meta-analysis followed the PRISMA guidelines. The databases PubMed, Embase, Cochrane Library, Web of science and Cinahl were searched for original studies comparing iNPWT to conventional wound dressing in patients undergoing VHR. The primary outcome was surgical site occurrence (SSO), secondary outcomes included surgical site infection (SSI) and hernia recurrence.

Results

The literature search identified 373 studies of which 10 were included in the meta-analysis including a total of 1087 patients. Eight studies were retrospective cohort studies, one was a cross-sectional pilot study, and one was a randomized controlled trial. The meta-analysis demonstrated that iNPWT was associated with a decreased risk of SSO (OR 0.27 [0.19, 0.38]; P < 0.001) and SSI (OR 0.32 [0.17, 0.55]; P < 0.001). There was no statistically significant association with the risk of hernia recurrence (OR 0.62 [0.27, 1.43]; P = 0.26).

Conclusion

Based on the findings of this systematic review and meta-analysis iNPWT following VHR was found to significantly reduce the incidence of SSO and SSI, compared with standard wound dressing. INPWT should be considered for patients undergoing VHR.

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Title: Prophylactic negative pressure wound therapy after open ventral hernia repair: a systematic review and meta-analysis
Authors: V. Berner-Hansen
E. Oma
M. Willaume
K. K. Jensen
Publication date: 01-12-2021
Publisher: Springer Paris
Keywords: Wound Dehiscence
Vacuum Therapy
Seroma
Vacuum Therapy
Vacuum Therapy
Incision
Incisional Hernia
Published in: Hernia / Issue 6/2021
Print ISSN: 1265-4906
Electronic ISSN: 1248-9204
DOI: https://doi.org/10.1007/s10029-021-02485-7

At a glance: The STEP trials

Springer Medicine

Prophylactic negative pressure wound therapy after open ventral hernia repair: a systematic review and meta-analysis

Abstract

Purpose

Materials and methods

Results

Conclusion

At a glance: The STEP trials

Springer Medicine

Abstract

Purpose

Materials and methods

Results

Conclusion

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