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Journal of Anesthesia
Published in: Journal of Anesthesia 2/2019

01-04-2019 | Cough | Original Article

Influence of intraoperative sevoflurane or desflurane on postoperative sore throat: a prospective randomized study

Authors: Ji-Hoon Park, Yong-Cheol Lee, Jiwon Lee, Sangbaek Kim, Hyun-Chang Kim

Published in: Journal of Anesthesia | Issue 2/2019

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Abstract

Purpose

Tracheal intubation for general anesthesia causes postoperative sore throat. The purpose of this study was to evaluate the effect of sevoflurane and desflurane on prevalence of postoperative sore throat in patients after general anesthesia.

Methods

Ninety-six patients scheduled for orthopedic lower extremity surgery under general anesthesia were assigned to sevoflurane group or desflurane group. In the sevoflurane group (n = 48), sevoflurane was used as a maintenance anesthetic agent. In the desflurane group (n = 48), desflurane was used. Prevalence of sore throat, number of patients with rescue analgesics, and analgesics requirements were evaluated.

Results

The overall prevalence of postoperative sore throat in the sevoflurane group was lower than that in the desflurane group [21 (44%) vs. 32 (67%), p = 0.024]. The prevalence of sore throat at postoperative 4 h in the sevoflurane group was lower than that in the desflurane group [6 (13%) vs. 18 (38%), p = 0.005]. The number of patients requiring rescue analgesics was lower in the sevoflurane group [25 (52%) vs. 36 (75%), p = 0.020]. The requirement of diclofenac was also lower in the sevoflurane group (30 ± 37 mg vs. 47 ± 40 mg, p = 0.031).

Conclusions

We have shown that sevoflurane was associated with less frequent sore throat than desflurane in patients undergoing orthopedic lower extremity surgery.
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Metadata
Title
Influence of intraoperative sevoflurane or desflurane on postoperative sore throat: a prospective randomized study
Authors
Ji-Hoon Park
Yong-Cheol Lee
Jiwon Lee
Sangbaek Kim
Hyun-Chang Kim
Publication date
01-04-2019
Publisher
Springer Japan
Published in
Journal of Anesthesia / Issue 2/2019
Print ISSN: 0913-8668
Electronic ISSN: 1438-8359
DOI
https://doi.org/10.1007/s00540-018-2600-y

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