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Published in: BMC Cardiovascular Disorders 1/2016

Open Access 01-12-2016 | Research article

Correlation between impedance cardiography and 6 min walk distance in atrial fibrillation patients

Authors: Ling Ding, Xiao-Qing Quan, Shu Zhang, Lei Ruan, Le Zhang, Kai Zheng, Wei-Wei Yu, Xiao-Fen Wu, Tao Mi, Cun-Tai Zhang, Hong-Lian Zhou

Published in: BMC Cardiovascular Disorders | Issue 1/2016

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Abstract

Background

The correlation between impedance cardiography (ICG) and 6 min walk distance (6MWD) in atrial fibrillation (AF) patients remains unknown.

Methods

We recruited 49 subjects in the study (21 AF patients and 28 patients without AF) and estimated hemodynamic parameters: cardiac output (CO), stroke volume (SV), stroke volume index (SVI), left stroke work (LSW), left stroke work index (LSWI), stroke systemic vascular resistance (SSVR), stroke systemic vascular resistance index (SSVRI); 6MWD, left ventricle ejection fraction (LVEF), NT-pro brain natriuretic peptide (NT-pro BNP) for the two groups.

Results

The AF group have apparently lower CO (2.26 ± 0.14 VS 4.11 ± 0.20 L/min, p = 0.039) and distinctly higher SVR (677.60 ± 69.10 VS 344.41 ± 22.98 dynes/cm5, p = 0.001), SSVRI (396.97 ± 36.80 VS 199.01 ± 11.72 dynes/cm5/m2, p < 0.001) than the control group. NT-pro BNP (1409.48 ± 239.90 VS 332.59 ± 68.85 pg/ml, p = 0.001) in the AF group was significantly higher than the control group and 6MWD (264.33 ± 14.55 VS 428.79 ± 29.98 m, p < 0.001) in the AF group was lower than the control group. There was no significant difference in LVEF between the two groups (62.67 ± 7.62 % VS 63.93 ± 5.03 %, p = 0.470). Pearson correlation analysis revealed that CO (R = 0.494, p = 0.023), SV (R = 0.633, p = 0.002), LSW (R = 0.615, p = 0.003) and LSWI (R = 0.491, p = 0.024) significantly correlated positively with 6MWD in AF patients.

Conclusions

AF patients had lower cardiac output, shorter 6MWD and higher NT-pro BNP than patients with sinus rhythm. The cardiac output measured by impedance cardiography significantly correlated positively with 6MWD in AF patients.
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Metadata
Title
Correlation between impedance cardiography and 6 min walk distance in atrial fibrillation patients
Authors
Ling Ding
Xiao-Qing Quan
Shu Zhang
Lei Ruan
Le Zhang
Kai Zheng
Wei-Wei Yu
Xiao-Fen Wu
Tao Mi
Cun-Tai Zhang
Hong-Lian Zhou
Publication date
01-12-2016
Publisher
BioMed Central
Published in
BMC Cardiovascular Disorders / Issue 1/2016
Electronic ISSN: 1471-2261
DOI
https://doi.org/10.1186/s12872-016-0297-0

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