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General Thoracic and Cardiovascular Surgery
Published in: General Thoracic and Cardiovascular Surgery 11/2019

01-11-2019 | Computed Tomography | Original Article

Sarcopenia predicts poor postoperative outcome in elderly patients with lung cancer

Authors: Yo Kawaguchi, Jun Hanaoka, Yasuhiko Ohshio, Keigo Okamoto, Ryosuke Kaku, Kazuki Hayashi, Takuya Shiratori, Makoto Yoden

Published in: General Thoracic and Cardiovascular Surgery | Issue 11/2019

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Abstract

Purpose

Sarcopenia gradually progress with age; hence, it is necessary to define sarcopenia to predict postoperative outcomes in elderly patients with lung cancer. The purpose of this study is to propose a definition of sarcopenia in elderly patients with lung cancer, and to demonstrate the post operative outcomes.

Methods

Using computed tomography scans, the cross-sectional area (cm2) of the psoas muscle at the third lumbar vertebral level was measured. The psoas area was normalized for height. The psoas muscle mass index was calculated as total psoas muscle area at L3 level/height2 (cm2/m2).

Results

A total of 173 patients aged > 75 years of age received lobectomy for non-small cell lung cancer in our hospital. We defined sarcopenia as the psoas muscle mass index under 3.70 cm2/m2 in males and 2.50 cm2/m2 in females, based on the morbidity rate. The postoperative complication rate was significantly higher in patients with sarcopenia (62.5%) than in those without sarcopenia (22.7%). The 5-year survival rate was 26.5% in patients with sarcopenia, and 66.3% in patients without sarcopenia.

Conclusions

In elderly lung cancer patients, sarcopenia was observed to be a high risk for morbidity and predicted poor prognosis.
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Metadata
Title
Sarcopenia predicts poor postoperative outcome in elderly patients with lung cancer
Authors
Yo Kawaguchi
Jun Hanaoka
Yasuhiko Ohshio
Keigo Okamoto
Ryosuke Kaku
Kazuki Hayashi
Takuya Shiratori
Makoto Yoden
Publication date
01-11-2019
Publisher
Springer Singapore
Published in
General Thoracic and Cardiovascular Surgery / Issue 11/2019
Print ISSN: 1863-6705
Electronic ISSN: 1863-6713
DOI
https://doi.org/10.1007/s11748-019-01125-3

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