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01-11-2019 | Computed Tomography | Interventional

Safety of percutaneous renal cryoablation: an international multicentre experience from the EuRECA retrospective percutaneous database

Authors: J. Garnon, M. J. Van Strijen, T. K. Nielsen, A. J. King, A. D. Montauban Van Swijndregt, R. L. Cazzato, P. Auloge, C. Rousseau, D. Dalili, F. X. Keeley Jr, B. W. Lagerveld, D. J. Breen

Published in: European Radiology | Issue 11/2019

Abstract

Objective

To investigate the safety profile of percutaneous cryoablation of renal tumours < 7 cm, utilising data extracted from an international multicentre registry.

Materials and methods

A retrospective review of all immediate and delayed complications from a multicentre database was performed and was categorised according to the Clavien-Dindo classification. Statistical analysis was performed for both overall complications (all Clavien-Dindo) and major complications (Clavien-Dindo 3 to 5). The following criteria were identified as potential predictive factors for complications: centre number, modality of image guidance, tumour size (≤ 4 cm vs. > 4 cm), number of tumours treated in the same session (1 vs. > 1) and tumour histology.

Results

A total of 713 renal tumours underwent ablation in 647 individual sessions. In 596 of the cases, one tumour was treated; in the remaining 51 cases, several tumours were treated per session. Mean lesion size was 2.8 cm. Fifty-four complications (Clavien-Dindo 1 to 5) occurred as a result of the 647 procedures, corresponding to an overall complication rate of 8.3%. The most frequent complication was bleeding (3.2%), with 9 cases (1.4%) requiring subsequent treatment. The rate of major complication was 3.4%. The only statistically significant prognostic factor for a major complication was a tumour size > 4 cm.

Conclusion

Percutaneous renal cryoablation is associated with a low rate of complications. Tumours measuring more than 4 cm are associated with a higher risk of major complications.

Key Points

• Percutaneous kidney cryoablation has a low rate of complications.

• Bleeding is the most frequent complication.

• A tumour size superior to 4 cm is a predictive factor of major complication.

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Title: Safety of percutaneous renal cryoablation: an international multicentre experience from the EuRECA retrospective percutaneous database
Authors: J. Garnon
M. J. Van Strijen
T. K. Nielsen
A. J. King
A. D. Montauban Van Swijndregt
R. L. Cazzato
P. Auloge
C. Rousseau
D. Dalili
F. X. Keeley Jr
B. W. Lagerveld
D. J. Breen
Publication date: 01-11-2019
Publisher: Springer Berlin Heidelberg
Keywords: Computed Tomography
Kidney Cancer
Kidney Cancer
Computed Tomography
Kidney Cancer
Published in: European Radiology / Issue 11/2019
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI: https://doi.org/10.1007/s00330-019-06191-y

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Safety of percutaneous renal cryoablation: an international multicentre experience from the EuRECA retrospective percutaneous database

Abstract

Objective

Materials and methods

Results

Conclusion

Key Points

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Objective

Materials and methods

Results

Conclusion

Key Points

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