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Published in: Knee Surgery, Sports Traumatology, Arthroscopy 12/2023

12-10-2023 | Computed Tomography | ANKLE

The use of deep learning enables high diagnostic accuracy in detecting syndesmotic instability on weight-bearing CT scanning

Authors: Alireza Borjali, Soheil Ashkani-Esfahani, Rohan Bhimani, Daniel Guss, Orhun K. Muratoglu, Christopher W. DiGiovanni, Kartik Mangudi Varadarajan, Bart Lubberts

Published in: Knee Surgery, Sports Traumatology, Arthroscopy | Issue 12/2023

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Abstract

Purpose

Delayed diagnosis of syndesmosis instability can lead to significant morbidity and accelerated arthritic change in the ankle joint. Weight-bearing computed tomography (WBCT) has shown promising potential for early and reliable detection of isolated syndesmotic instability using 3D volumetric measurements. While these measurements have been reported to be highly accurate, they are also experience-dependent, time-consuming, and need a particular 3D measurement software tool that leads the clinicians to still show more interest in the conventional diagnostic methods for syndesmotic instability. The purpose of this study was to increase accuracy, accelerate analysis time, and reduce interobserver bias by automating 3D volume assessment of syndesmosis anatomy using WBCT scans.

Methods

A retrospective study was conducted using previously collected WBCT scans of patients with unilateral syndesmotic instability. One-hundred and forty-four bilateral ankle WBCT scans were evaluated (48 unstable, 96 control). We developed three deep learning models for analyzing WBCT scans to recognize syndesmosis instability. These three models included two state-of-the-art models (Model 1—3D Convolutional Neural Network [CNN], and Model 2—CNN with long short-term memory [LSTM]), and a new model (Model 3—differential CNN LSTM) that we introduced in this study.

Results

Model 1 failed to analyze the WBCT scans (F1 score = 0). Model 2 only misclassified two cases (F1 score = 0.80). Model 3 outperformed Model 2 and achieved a nearly perfect performance, misclassifying only one case (F1 score = 0.91) in the control group as unstable while being faster than Model 2.

Conclusions

In this study, a deep learning model for 3D WBCT syndesmosis assessment was developed that achieved very high accuracy and accelerated analytics. This deep learning model shows promise for use by clinicians to improve diagnostic accuracy, reduce measurement bias, and save both time and expenditure for the healthcare system.

Level of evidence

II.
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Metadata
Title
The use of deep learning enables high diagnostic accuracy in detecting syndesmotic instability on weight-bearing CT scanning
Authors
Alireza Borjali
Soheil Ashkani-Esfahani
Rohan Bhimani
Daniel Guss
Orhun K. Muratoglu
Christopher W. DiGiovanni
Kartik Mangudi Varadarajan
Bart Lubberts
Publication date
12-10-2023
Publisher
Springer Berlin Heidelberg
Published in
Knee Surgery, Sports Traumatology, Arthroscopy / Issue 12/2023
Print ISSN: 0942-2056
Electronic ISSN: 1433-7347
DOI
https://doi.org/10.1007/s00167-023-07565-y

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