Skip to main content
Top
Published in: BMC Medical Imaging 1/2021

Open Access 01-12-2021 | Computed Tomography | Research

Image quality assessment of pediatric chest and abdomen CT by deep learning reconstruction

Authors: Haesung Yoon, Jisoo Kim, Hyun Ji Lim, Mi-Jung Lee

Published in: BMC Medical Imaging | Issue 1/2021

Login to get access

Abstract

Background

Efforts to reduce the radiation dose have continued steadily, with new reconstruction techniques. Recently, image denoising algorithms using artificial neural networks, termed deep learning reconstruction (DLR), have been applied to CT image reconstruction to overcome the drawbacks of iterative reconstruction (IR). The purpose of our study was to compare the objective and subjective image quality of DLR and IR on pediatric abdomen and chest CT images.

Methods

This retrospective study included pediatric body CT images from February 2020 to October 2020, performed on 51 patients (34 boys and 17 girls; age 1–18 years). Non-contrast chest CT (n = 16), contrast-enhanced chest CT (n = 12), and contrast-enhanced abdomen CT (n = 23) images were included. Standard 50% adaptive statistical iterative reconstruction V (ASIR-V) images were compared to images with 100% ASIR-V and DLR at medium and high strengths. Attenuation, noise, contrast to noise ratio (CNR), and signal to noise (SNR) measurements were performed. Overall image quality, artifacts, and noise were subjectively assessed by two radiologists using a four-point scale (superior, average, suboptimal, and unacceptable). A phantom scan was performed including the dose range of the clinical images used in our study, and the noise power spectrum (NPS) was calculated. Quantitative and qualitative parameters were compared using repeated-measures analysis of variance (ANOVA) with Bonferroni correction and Wilcoxon signed-rank tests.

Results

DLR had better CNR and SNR than 50% ASIR-V in both pediatric chest and abdomen CT images. When compared with 50% ASIR-V, high strength DLR was associated with noise reduction in non-contrast chest CT (33.0%), contrast-enhanced chest CT (39.6%), and contrast-enhanced abdomen CT (38.7%) with increases in CNR at 149.1%, 105.8%, and 53.1% respectively. The subjective assessment of overall image quality and the noise was also better on DLR images (p < 0.001). However, there was no significant difference in artifacts between reconstruction methods. From NPS analysis, DLR methods showed a pattern of reducing the magnitude of noise while maintaining the texture.

Conclusion

Compared with 50% ASIR-V, DLR improved pediatric body CT images with significant noise reduction. However, artifacts were not improved by DLR, regardless of strength.
Appendix
Available only for authorised users
Literature
1.
go back to reference Yanagawa M, Honda O, Kikuyama A, Gyobu T, Sumikawa H, Koyama M, Tomiyama N. Pulmonary nodules: effect of adaptive statistical iterative reconstruction (ASIR) technique on performance of a computer-aided detection (CAD) system-comparison of performance between different-dose CT scans. Eur J Radiol. 2012;81(10):2877–86.CrossRef Yanagawa M, Honda O, Kikuyama A, Gyobu T, Sumikawa H, Koyama M, Tomiyama N. Pulmonary nodules: effect of adaptive statistical iterative reconstruction (ASIR) technique on performance of a computer-aided detection (CAD) system-comparison of performance between different-dose CT scans. Eur J Radiol. 2012;81(10):2877–86.CrossRef
2.
go back to reference Singh S, Kalra MK, Hsieh J, Licato PE, Do S, Pien HH, Blake MA. Abdominal CT: comparison of adaptive statistical iterative and filtered back projection reconstruction techniques. Radiology. 2010;257(2):373–83.CrossRef Singh S, Kalra MK, Hsieh J, Licato PE, Do S, Pien HH, Blake MA. Abdominal CT: comparison of adaptive statistical iterative and filtered back projection reconstruction techniques. Radiology. 2010;257(2):373–83.CrossRef
3.
go back to reference Bae S, Kim MJ, Yoon CS, Kim DW, Hong JH, Lee MJ. Effects of adaptive statistical iterative reconstruction on radiation dose reduction and diagnostic accuracy of pediatric abdominal CT. Pediatr Radiol. 2014;44(12):1541–7.CrossRef Bae S, Kim MJ, Yoon CS, Kim DW, Hong JH, Lee MJ. Effects of adaptive statistical iterative reconstruction on radiation dose reduction and diagnostic accuracy of pediatric abdominal CT. Pediatr Radiol. 2014;44(12):1541–7.CrossRef
4.
go back to reference Yoon H, Kim MJ, Yoon CS, Choi J, Shin HJ, Kim HG, Lee MJ. Radiation dose and image quality in pediatric chest CT: effects of iterative reconstruction in normal weight and overweight children. Pediatr Radiol. 2015;45(3):337–44.CrossRef Yoon H, Kim MJ, Yoon CS, Choi J, Shin HJ, Kim HG, Lee MJ. Radiation dose and image quality in pediatric chest CT: effects of iterative reconstruction in normal weight and overweight children. Pediatr Radiol. 2015;45(3):337–44.CrossRef
5.
go back to reference Lee SH, Kim MJ, Yoon CS, Lee MJ. Radiation dose reduction with the adaptive statistical iterative reconstruction (ASIR) technique for chest CT in children: an intra-individual comparison. Eur J Radiol. 2012;81(9):e938-943.CrossRef Lee SH, Kim MJ, Yoon CS, Lee MJ. Radiation dose reduction with the adaptive statistical iterative reconstruction (ASIR) technique for chest CT in children: an intra-individual comparison. Eur J Radiol. 2012;81(9):e938-943.CrossRef
6.
go back to reference Singh S, Kalra MK, Shenoy-Bhangle AS, Saini A, Gervais DA, Westra SJ, Thrall JH. Radiation dose reduction with hybrid iterative reconstruction for pediatric CT. Radiology. 2012;263(2):537–46.CrossRef Singh S, Kalra MK, Shenoy-Bhangle AS, Saini A, Gervais DA, Westra SJ, Thrall JH. Radiation dose reduction with hybrid iterative reconstruction for pediatric CT. Radiology. 2012;263(2):537–46.CrossRef
7.
go back to reference Goodenberger MH, Wagner-Bartak NA, Gupta S, Liu X, Yap RQ, Sun J, Tamm EP, Jensen CT. Computed tomography image quality evaluation of a new iterative reconstruction algorithm in the abdomen (adaptive statistical iterative reconstruction-V) a comparison with model-based iterative reconstruction, adaptive statistical iterative reconstruction, and filtered back projection reconstructions. J Comput Assist Tomogr. 2018;42(2):184–90.CrossRef Goodenberger MH, Wagner-Bartak NA, Gupta S, Liu X, Yap RQ, Sun J, Tamm EP, Jensen CT. Computed tomography image quality evaluation of a new iterative reconstruction algorithm in the abdomen (adaptive statistical iterative reconstruction-V) a comparison with model-based iterative reconstruction, adaptive statistical iterative reconstruction, and filtered back projection reconstructions. J Comput Assist Tomogr. 2018;42(2):184–90.CrossRef
8.
go back to reference Euler A, Solomon J, Marin D, Nelson RC, Samei E. A third-generation adaptive statistical iterative reconstruction technique: phantom study of image noise, spatial resolution, lesion detectability, and dose reduction potential. AJR Am J Roentgenol. 2018;210(6):1301–8.CrossRef Euler A, Solomon J, Marin D, Nelson RC, Samei E. A third-generation adaptive statistical iterative reconstruction technique: phantom study of image noise, spatial resolution, lesion detectability, and dose reduction potential. AJR Am J Roentgenol. 2018;210(6):1301–8.CrossRef
9.
go back to reference Padole A, Ali Khawaja RD, Kalra MK, Singh S. CT radiation dose and iterative reconstruction techniques. AJR Am J Roentgenol. 2015;204(4):W384-392.CrossRef Padole A, Ali Khawaja RD, Kalra MK, Singh S. CT radiation dose and iterative reconstruction techniques. AJR Am J Roentgenol. 2015;204(4):W384-392.CrossRef
10.
go back to reference Akagi M, Nakamura Y, Higaki T, Narita K, Honda Y, Zhou J, Yu Z, Akino N, Awai K. Deep learning reconstruction improves image quality of abdominal ultra-high-resolution CT. Eur Radiol. 2019;29(11):6163–71.CrossRef Akagi M, Nakamura Y, Higaki T, Narita K, Honda Y, Zhou J, Yu Z, Akino N, Awai K. Deep learning reconstruction improves image quality of abdominal ultra-high-resolution CT. Eur Radiol. 2019;29(11):6163–71.CrossRef
11.
go back to reference Greffier J, Hamard A, Pereira F, Barrau C, Pasquier H, Beregi JP, Frandon J. Image quality and dose reduction opportunity of deep learning image reconstruction algorithm for CT: a phantom study. Eur Radiol. 2020;30(7):3951–9.CrossRef Greffier J, Hamard A, Pereira F, Barrau C, Pasquier H, Beregi JP, Frandon J. Image quality and dose reduction opportunity of deep learning image reconstruction algorithm for CT: a phantom study. Eur Radiol. 2020;30(7):3951–9.CrossRef
12.
go back to reference Jensen CT, Liu X, Tamm EP, Chandler AG, Sun J, Morani AC, Javadi S, Wagner-Bartak NA. Image quality assessment of abdominal CT by use of new deep learning image reconstruction: initial experience. AJR Am J Roentgenol. 2020;215(1):50–7.CrossRef Jensen CT, Liu X, Tamm EP, Chandler AG, Sun J, Morani AC, Javadi S, Wagner-Bartak NA. Image quality assessment of abdominal CT by use of new deep learning image reconstruction: initial experience. AJR Am J Roentgenol. 2020;215(1):50–7.CrossRef
13.
go back to reference Park C, Choo KS, Jung Y, Jeong HS, Hwang JY, Yun MS. CT iterative vs deep learning reconstruction: comparison of noise and sharpness. Eur Radiol. 2020;6:66. Park C, Choo KS, Jung Y, Jeong HS, Hwang JY, Yun MS. CT iterative vs deep learning reconstruction: comparison of noise and sharpness. Eur Radiol. 2020;6:66.
14.
go back to reference Shin YJ, Chang W, Ye JC, Kang E, Oh DY, Lee YJ, Park JH, Kim YH. Low-dose abdominal CT using a deep learning-based denoising algorithm: a comparison with CT reconstructed with filtered back projection or iterative reconstruction algorithm. Korean J Radiol. 2020;21(3):356–64.CrossRef Shin YJ, Chang W, Ye JC, Kang E, Oh DY, Lee YJ, Park JH, Kim YH. Low-dose abdominal CT using a deep learning-based denoising algorithm: a comparison with CT reconstructed with filtered back projection or iterative reconstruction algorithm. Korean J Radiol. 2020;21(3):356–64.CrossRef
15.
go back to reference Singh R, Digumarthy SR, Muse VV, Kambadakone AR, Blake MA, Tabari A, Hoi Y, Akino N, Angel E, Madan R, et al. Image quality and lesion detection on deep learning reconstruction and iterative reconstruction of submillisievert chest and abdominal CT. AJR Am J Roentgenol. 2020;214(3):566–73.CrossRef Singh R, Digumarthy SR, Muse VV, Kambadakone AR, Blake MA, Tabari A, Hoi Y, Akino N, Angel E, Madan R, et al. Image quality and lesion detection on deep learning reconstruction and iterative reconstruction of submillisievert chest and abdominal CT. AJR Am J Roentgenol. 2020;214(3):566–73.CrossRef
16.
go back to reference Lim WH, Choi YH, Park JE, Cho YJ, Lee S, Cheon JE, Kim WS, Kim IO, Kim JH. Application of vendor-neutral iterative reconstruction technique to pediatric abdominal computed tomography. Korean J Radiol. 2019;20(9):1358–67.CrossRef Lim WH, Choi YH, Park JE, Cho YJ, Lee S, Cheon JE, Kim WS, Kim IO, Kim JH. Application of vendor-neutral iterative reconstruction technique to pediatric abdominal computed tomography. Korean J Radiol. 2019;20(9):1358–67.CrossRef
17.
go back to reference Brady SL, Trout AT, Somasundaram E, Anton CG, Li Y, Dillman JR. Improving image quality and reducing radiation dose for pediatric CT by using deep learning reconstruction. Radiology. 2020;66:202317. Brady SL, Trout AT, Somasundaram E, Anton CG, Li Y, Dillman JR. Improving image quality and reducing radiation dose for pediatric CT by using deep learning reconstruction. Radiology. 2020;66:202317.
18.
go back to reference Lee S, Choi YH, Cho YJ, Lee SB, Cheon JE, Kim WS, Ahn CK, Kim JH. Noise reduction approach in pediatric abdominal CT combining deep learning and dual-energy technique. Eur Radiol. 2020;6:66. Lee S, Choi YH, Cho YJ, Lee SB, Cheon JE, Kim WS, Ahn CK, Kim JH. Noise reduction approach in pediatric abdominal CT combining deep learning and dual-energy technique. Eur Radiol. 2020;6:66.
19.
go back to reference Kijewski MF, Judy PF. The noise power spectrum of CT images. Phys Med Biol. 1987;32(5):565–75.CrossRef Kijewski MF, Judy PF. The noise power spectrum of CT images. Phys Med Biol. 1987;32(5):565–75.CrossRef
20.
go back to reference Friedman SN, Fung GS, Siewerdsen JH, Tsui BM. A simple approach to measure computed tomography (CT) modulation transfer function (MTF) and noise-power spectrum (NPS) using the American College of Radiology (ACR) accreditation phantom. Med Phys. 2013;40(5):051907.CrossRef Friedman SN, Fung GS, Siewerdsen JH, Tsui BM. A simple approach to measure computed tomography (CT) modulation transfer function (MTF) and noise-power spectrum (NPS) using the American College of Radiology (ACR) accreditation phantom. Med Phys. 2013;40(5):051907.CrossRef
22.
go back to reference Boone J SK, Cody D et al: Size-specific dose estimates (SSDE) in pediatric and adult body CT examinations. 2011. Boone J SK, Cody D et al: Size-specific dose estimates (SSDE) in pediatric and adult body CT examinations. 2011.
23.
go back to reference Deak PD, Smal Y, Kalender WA. Multisection CT protocols: sex- and age-specific conversion factors used to determine effective dose from dose-length product. Radiology. 2010;257(1):158–66.CrossRef Deak PD, Smal Y, Kalender WA. Multisection CT protocols: sex- and age-specific conversion factors used to determine effective dose from dose-length product. Radiology. 2010;257(1):158–66.CrossRef
24.
go back to reference Greffier J, Pereira F, Macri F, Beregi J-P, Larbi A. CT dose reduction using automatic exposure control and iterative reconstruction: a chest paediatric phantoms study. Physica Med. 2016;32(4):582–9.CrossRef Greffier J, Pereira F, Macri F, Beregi J-P, Larbi A. CT dose reduction using automatic exposure control and iterative reconstruction: a chest paediatric phantoms study. Physica Med. 2016;32(4):582–9.CrossRef
25.
go back to reference Chen Y, Shi L, Feng Q, Yang J, Shu H, Luo L, Coatrieux J, Chen W. Artifact suppressed dictionary learning for low-dose CT image processing. IEEE Trans Med Imaging. 2014;33(12):2271–92.CrossRef Chen Y, Shi L, Feng Q, Yang J, Shu H, Luo L, Coatrieux J, Chen W. Artifact suppressed dictionary learning for low-dose CT image processing. IEEE Trans Med Imaging. 2014;33(12):2271–92.CrossRef
26.
go back to reference Yin X, Zhao Q, Liu J, Yang W, Yang J, Quan G, Chen Y, Shu H, Luo L, Coatrieux JL. Domain progressive 3D residual convolution network to improve low-dose CT imaging. IEEE Trans Med Imaging. 2019;38(12):2903–13.CrossRef Yin X, Zhao Q, Liu J, Yang W, Yang J, Quan G, Chen Y, Shu H, Luo L, Coatrieux JL. Domain progressive 3D residual convolution network to improve low-dose CT imaging. IEEE Trans Med Imaging. 2019;38(12):2903–13.CrossRef
27.
go back to reference Liu J, Ma J, Zhang Y, Chen Y, Yang J, Shu H, Luo L, Coatrieux G, Yang W, Feng Q, et al. Discriminative feature representation to improve projection data inconsistency for low dose CT imaging. IEEE Trans Med Imaging. 2017;36(12):2499–509.CrossRef Liu J, Ma J, Zhang Y, Chen Y, Yang J, Shu H, Luo L, Coatrieux G, Yang W, Feng Q, et al. Discriminative feature representation to improve projection data inconsistency for low dose CT imaging. IEEE Trans Med Imaging. 2017;36(12):2499–509.CrossRef
28.
go back to reference Nam JG, Hong JH, Kim DS, Oh J, Goo JM. Deep learning reconstruction for contrast-enhanced CT of the upper abdomen: similar image quality with lower radiation dose in direct comparison with iterative reconstruction. Eur Radiol. 2021;6:66. Nam JG, Hong JH, Kim DS, Oh J, Goo JM. Deep learning reconstruction for contrast-enhanced CT of the upper abdomen: similar image quality with lower radiation dose in direct comparison with iterative reconstruction. Eur Radiol. 2021;6:66.
Metadata
Title
Image quality assessment of pediatric chest and abdomen CT by deep learning reconstruction
Authors
Haesung Yoon
Jisoo Kim
Hyun Ji Lim
Mi-Jung Lee
Publication date
01-12-2021
Publisher
BioMed Central
Published in
BMC Medical Imaging / Issue 1/2021
Electronic ISSN: 1471-2342
DOI
https://doi.org/10.1186/s12880-021-00677-2

Other articles of this Issue 1/2021

BMC Medical Imaging 1/2021 Go to the issue