Skip to main content
Top
Published in: Emergency Radiology 1/2024

13-12-2023 | Computed Tomography | Original Article

CT esophagogram in the emergency setting: typical findings and suggested workflow

Authors: Brad A. Evans, Wendy Y. Craig, Christina M. Cinelli, Sharon G. Siegel

Published in: Emergency Radiology | Issue 1/2024

Login to get access

Abstract

Purpose

Esophageal perforation (EP) can be a diagnostic challenge. Computed tomography (CT) and CT esophagography (CTE) are often used to rule out EP in the emergency setting with promising diagnostic performance, but the standard of care remains fluoroscopic esophagography (FE). We assess the diagnostic performance of CT and CTE when interpreted by expert and generalist radiologists and created an imaging workflow guide.

Methods

Retrospective study of patients presenting with suspected EP. Two expert radiologists independently reviewed blinded CT/CTE studies, recorded CT findings, and assigned an esophageal injury grade. We also collected initial (general radiologist) CT findings and interpretation and FE diagnoses. We assessed inter-reader reliability and diagnostic performance.

Results

EP was diagnosed in 46/139 (33%) encounters. The most common CT/CTE findings in EP were esophageal wall thickening (46/46, 100%), pneumomediastinum (42/46, 91%), and mediastinal stranding (39/46, 85%). CT and CTE sensitivity for detecting EP was 89% and 89% for expert radiologists, respectively, and 79% and 82% for general radiologists, compared with 46% for FE. Inter-reader agreement for detecting EP by CT and CTE was kappa 0.35 and 0.42 (both p < .001) between expert and generalist radiologists. We present radiographic images for key CT/CTE findings and a suggested workflow for the evaluation of possible EP.

Conclusion

CT and CTE are more sensitive than FE for EP in the emergency setting. Due to the rarity of EP and current wide variability in imaging interpretation, an imaging workflow and injury grading system based on esophageal and mediastinal CT findings are offered to help guide management.
Appendix
Available only for authorised users
Literature
1.
go back to reference Sohda M, Kuwano H, Sakai M, Miyazaki T, Kakeji Y, Toh Y et al (2020) A national survey on esophageal perforation: study of cases at accredited institutions by the Japanese Esophagus Society. Esophagus 17(3):230–238CrossRefPubMed Sohda M, Kuwano H, Sakai M, Miyazaki T, Kakeji Y, Toh Y et al (2020) A national survey on esophageal perforation: study of cases at accredited institutions by the Japanese Esophagus Society. Esophagus 17(3):230–238CrossRefPubMed
2.
go back to reference DeVivo A, Sheng AY, Koyfman A, Long B (2022) High risk and low prevalence diseases: esophageal perforation. Am J Emerg Med 53:29–36CrossRefPubMed DeVivo A, Sheng AY, Koyfman A, Long B (2022) High risk and low prevalence diseases: esophageal perforation. Am J Emerg Med 53:29–36CrossRefPubMed
3.
4.
go back to reference Soreide JA, Viste A (2011) Esophageal perforation: diagnostic work-up and clinical decision-making in the first 24 hours. Scand J Trauma Resusc Emerg Med 19:66CrossRefPubMedPubMedCentral Soreide JA, Viste A (2011) Esophageal perforation: diagnostic work-up and clinical decision-making in the first 24 hours. Scand J Trauma Resusc Emerg Med 19:66CrossRefPubMedPubMedCentral
5.
go back to reference Kaman L, Iqbal J, Kundil B, Kochhar R (2010) Management of esophageal perforation in adults. Gastroenterology Res 3(6):235–244PubMedPubMedCentral Kaman L, Iqbal J, Kundil B, Kochhar R (2010) Management of esophageal perforation in adults. Gastroenterology Res 3(6):235–244PubMedPubMedCentral
6.
go back to reference Brinster CJ, Singhal S, Lee L, Marshall MB, Kaiser LR, Kucharczuk JC (2004) Evolving options in the management of esophageal perforation. Ann Thorac Surg 77(4):1475–1483CrossRefPubMed Brinster CJ, Singhal S, Lee L, Marshall MB, Kaiser LR, Kucharczuk JC (2004) Evolving options in the management of esophageal perforation. Ann Thorac Surg 77(4):1475–1483CrossRefPubMed
7.
go back to reference Vermeulen BD, van der Leeden B, Ali JT, Gudbjartsson T, Hermansson M, Low DE et al (2021) Early diagnosis is associated with improved clinical outcomes in benign esophageal perforation: an individual patient data meta-analysis. Surg Endosc 35(7):3492–3505CrossRefPubMed Vermeulen BD, van der Leeden B, Ali JT, Gudbjartsson T, Hermansson M, Low DE et al (2021) Early diagnosis is associated with improved clinical outcomes in benign esophageal perforation: an individual patient data meta-analysis. Surg Endosc 35(7):3492–3505CrossRefPubMed
8.
go back to reference Puerta Vicente A, Priego Jimenez P, Cornejo Lopez MA, Garcia-Moreno Nisa F, Rodriguez Velasco G, Galindo Alvarez J et al (2018) Management of esophageal perforation: 28-year experience in a major referral center. Am Surg 84(5):684–689CrossRefPubMed Puerta Vicente A, Priego Jimenez P, Cornejo Lopez MA, Garcia-Moreno Nisa F, Rodriguez Velasco G, Galindo Alvarez J et al (2018) Management of esophageal perforation: 28-year experience in a major referral center. Am Surg 84(5):684–689CrossRefPubMed
9.
go back to reference Sdralis EIK, Petousis S, Rashid F, Lorenzi B, Charalabopoulos A (2017) Epidemiology, diagnosis, and management of esophageal perforations: systematic review. Dis Esophagus 30(8):1–6CrossRefPubMed Sdralis EIK, Petousis S, Rashid F, Lorenzi B, Charalabopoulos A (2017) Epidemiology, diagnosis, and management of esophageal perforations: systematic review. Dis Esophagus 30(8):1–6CrossRefPubMed
10.
go back to reference Yeh DD, Hwabejire JO, de Moya M, King DR, Fagenholz P, Kaafarani HM et al (2015) Preoperative evaluation of penetrating esophageal trauma in the current era: an analysis of the National Trauma Data Bank. J Emerg Trauma Shock 8(1):30–33CrossRefPubMedPubMedCentral Yeh DD, Hwabejire JO, de Moya M, King DR, Fagenholz P, Kaafarani HM et al (2015) Preoperative evaluation of penetrating esophageal trauma in the current era: an analysis of the National Trauma Data Bank. J Emerg Trauma Shock 8(1):30–33CrossRefPubMedPubMedCentral
11.
go back to reference Fadoo F, Ruiz DE, Dawn SK, Webb WR, Gotway MB (2004) Helical CT esophagography for the evaluation of suspected esophageal perforation or rupture. AJR Am J Roentgenol 182(5):1177–1179CrossRefPubMed Fadoo F, Ruiz DE, Dawn SK, Webb WR, Gotway MB (2004) Helical CT esophagography for the evaluation of suspected esophageal perforation or rupture. AJR Am J Roentgenol 182(5):1177–1179CrossRefPubMed
12.
go back to reference Wei CJ, Levenson RB, Lee KS (2020) Diagnostic utility of CT and fluoroscopic esophagography for suspected esophageal perforation in the emergency department. AJR Am J Roentgenol 215(3):631–638CrossRefPubMed Wei CJ, Levenson RB, Lee KS (2020) Diagnostic utility of CT and fluoroscopic esophagography for suspected esophageal perforation in the emergency department. AJR Am J Roentgenol 215(3):631–638CrossRefPubMed
13.
go back to reference Levy AD CL, Bartel TB et al (2019) ACR Appropriateness Criteria® Dysphagia. Accessed 5 Apr 2022 Levy AD CL, Bartel TB et al (2019) ACR Appropriateness Criteria® Dysphagia. Accessed 5 Apr 2022
14.
go back to reference Norton-Gregory AA, Kulkarni NM, O’Connor SD, Budovec JJ, Zorn AP, Desouches SL (2021) CT esophagography for evaluation of esophageal perforation. Radiographics 41(2):447–461CrossRefPubMed Norton-Gregory AA, Kulkarni NM, O’Connor SD, Budovec JJ, Zorn AP, Desouches SL (2021) CT esophagography for evaluation of esophageal perforation. Radiographics 41(2):447–461CrossRefPubMed
16.
go back to reference Suarez-Poveda T, Morales-Uribe CH, Sanabria A, Llano-Sanchez A, Valencia-Delgado AM, Rivera-Velazquez LF et al (2014) Diagnostic performance of CT esophagography in patients with suspected esophageal rupture. Emerg Radiol 21(5):505–510CrossRefPubMed Suarez-Poveda T, Morales-Uribe CH, Sanabria A, Llano-Sanchez A, Valencia-Delgado AM, Rivera-Velazquez LF et al (2014) Diagnostic performance of CT esophagography in patients with suspected esophageal rupture. Emerg Radiol 21(5):505–510CrossRefPubMed
17.
go back to reference Terrazas M, Marjon L, Geter M, Schwartz J, Thompson W (2020) Esophagography and chest CT for detection of perforated esophagus: what factors influence accuracy? Abdom Radiol (NY) 45(10):2980–2988CrossRefPubMed Terrazas M, Marjon L, Geter M, Schwartz J, Thompson W (2020) Esophagography and chest CT for detection of perforated esophagus: what factors influence accuracy? Abdom Radiol (NY) 45(10):2980–2988CrossRefPubMed
18.
go back to reference Young CA, Menias CO, Bhalla S, Prasad SR (2008) CT features of esophageal emergencies. Radiographics 28(6):1541–1553CrossRefPubMed Young CA, Menias CO, Bhalla S, Prasad SR (2008) CT features of esophageal emergencies. Radiographics 28(6):1541–1553CrossRefPubMed
19.
go back to reference Lee S, Mergo PJ, Ros PR (1996) The leaking esophagus: CT patterns of esophageal rupture, perforation, and fistulization. Crit Rev Diagn Imaging 37(6):461–490PubMed Lee S, Mergo PJ, Ros PR (1996) The leaking esophagus: CT patterns of esophageal rupture, perforation, and fistulization. Crit Rev Diagn Imaging 37(6):461–490PubMed
20.
go back to reference Axtell AL, Gaissert HA, Morse CR, Premkumar A, Schumacher L, Muniappan A et al (2022) Management and outcomes of esophageal perforation. Dis Esophagus 2022:35(1) Axtell AL, Gaissert HA, Morse CR, Premkumar A, Schumacher L, Muniappan A et al (2022) Management and outcomes of esophageal perforation. Dis Esophagus 2022:35(1)
21.
go back to reference Conradie WJ, Gebremariam FA (2015) Can computed tomography esophagography reliably diagnose traumatic penetrating upper digestive tract injuries? Clin Imaging 39(6):1039–1045CrossRefPubMed Conradie WJ, Gebremariam FA (2015) Can computed tomography esophagography reliably diagnose traumatic penetrating upper digestive tract injuries? Clin Imaging 39(6):1039–1045CrossRefPubMed
22.
go back to reference Wu CH, Chen CM, Chen CC, Wong YC, Wang CJ, Lo WC et al (2013) Esophagography after pneumomediastinum without CT findings of esophageal perforation: is it necessary? AJR Am J Roentgenol 201(5):977–984CrossRefPubMed Wu CH, Chen CM, Chen CC, Wong YC, Wang CJ, Lo WC et al (2013) Esophagography after pneumomediastinum without CT findings of esophageal perforation: is it necessary? AJR Am J Roentgenol 201(5):977–984CrossRefPubMed
23.
go back to reference Awais M, Qamar S, Rehman A, Baloch NU, Shafqat G (2019) Accuracy of CT chest without oral contrast for ruling out esophageal perforation using fluoroscopic esophagography as reference standard: a retrospective study. Eur J Trauma Emerg Surg 45(3):517–525CrossRefPubMed Awais M, Qamar S, Rehman A, Baloch NU, Shafqat G (2019) Accuracy of CT chest without oral contrast for ruling out esophageal perforation using fluoroscopic esophagography as reference standard: a retrospective study. Eur J Trauma Emerg Surg 45(3):517–525CrossRefPubMed
24.
go back to reference Lutio De, di Castelguidone E, Pinto A, Merola S, Stavolo C, Romano L (2005) Role of spiral and multislice computed tomography in the evaluation of traumatic and spontaneous oesophageal perforation. Our experience. Radiol Med. 109(3):252–9 Lutio De, di Castelguidone E, Pinto A, Merola S, Stavolo C, Romano L (2005) Role of spiral and multislice computed tomography in the evaluation of traumatic and spontaneous oesophageal perforation. Our experience. Radiol Med. 109(3):252–9
25.
go back to reference Moletta L, Pierobon ES, Capovilla G, Valotto G, Gavagna L, Provenzano L et al (2022) Could the Pittsburgh Severity Score guide the treatment of esophageal perforation? Experience of a single referral center. J Trauma Acute Care Surg 92(1):108–116CrossRefPubMed Moletta L, Pierobon ES, Capovilla G, Valotto G, Gavagna L, Provenzano L et al (2022) Could the Pittsburgh Severity Score guide the treatment of esophageal perforation? Experience of a single referral center. J Trauma Acute Care Surg 92(1):108–116CrossRefPubMed
26.
go back to reference Fuhrmann C, Weissenborn M, Salman S (2021) Mediastinal fluid as a predictor for esophageal perforation as the cause of pneumomediastinum. Emerg Radiol 28(2):233–238CrossRefPubMed Fuhrmann C, Weissenborn M, Salman S (2021) Mediastinal fluid as a predictor for esophageal perforation as the cause of pneumomediastinum. Emerg Radiol 28(2):233–238CrossRefPubMed
27.
go back to reference Ho AS, Ahmed A, Huang JS, Menias CO, Bhalla S (2012) Multidetector computed tomography of spontaneous versus secondary pneumomediastinum in 89 patients: can multidetector computed tomography be used to reliably distinguish between the 2 entities? J Thorac Imaging 27(2):85–92CrossRefPubMed Ho AS, Ahmed A, Huang JS, Menias CO, Bhalla S (2012) Multidetector computed tomography of spontaneous versus secondary pneumomediastinum in 89 patients: can multidetector computed tomography be used to reliably distinguish between the 2 entities? J Thorac Imaging 27(2):85–92CrossRefPubMed
28.
go back to reference Morgan CT, Maloney JD, Decamp MM, McCarthy DP (2021) A narrative review of primary spontaneous pneumomediastinum: a poorly understood and resource-intensive problem. J Thorac Dis 13(6):3721–3730CrossRefPubMedPubMedCentral Morgan CT, Maloney JD, Decamp MM, McCarthy DP (2021) A narrative review of primary spontaneous pneumomediastinum: a poorly understood and resource-intensive problem. J Thorac Dis 13(6):3721–3730CrossRefPubMedPubMedCentral
29.
go back to reference Lantos JE, Levine MS, Rubesin SE, Lau CT, Torigian DA (2013) Comparison between esophagography and chest computed tomography for evaluation of leaks after esophagectomy and gastric pull-through. J Thorac Imaging 28(2):121–128CrossRefPubMed Lantos JE, Levine MS, Rubesin SE, Lau CT, Torigian DA (2013) Comparison between esophagography and chest computed tomography for evaluation of leaks after esophagectomy and gastric pull-through. J Thorac Imaging 28(2):121–128CrossRefPubMed
Metadata
Title
CT esophagogram in the emergency setting: typical findings and suggested workflow
Authors
Brad A. Evans
Wendy Y. Craig
Christina M. Cinelli
Sharon G. Siegel
Publication date
13-12-2023
Publisher
Springer International Publishing
Published in
Emergency Radiology / Issue 1/2024
Print ISSN: 1070-3004
Electronic ISSN: 1438-1435
DOI
https://doi.org/10.1007/s10140-023-02193-y

Other articles of this Issue 1/2024

Emergency Radiology 1/2024 Go to the issue