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BMC Cancer
Published in: BMC Cancer 1/2024

Open Access 01-12-2024 | Computed Tomography | Research

COVID-19 and cancer risk arising from ionizing radiation exposure through CT scans: a cross-sectional study

Authors: Golshan Mahmoudi, Heidar Toolee, Reza Maskani, Farzaneh Jokar, Milad Mokfi, Ali Hosseinzadeh

Published in: BMC Cancer | Issue 1/2024

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Abstract

Background

The surge in the utilization of CT scans for COVID-19 diagnosis and monitoring during the pandemic is undeniable. This increase has brought to the forefront concerns about the potential long-term health consequences, especially radiation-induced cancer risk. This study aimed to quantify the potential cancer risk associated with CT scans performed for COVID-19 detection.

Methods

In this cross-sectional study data from a total of 561 patients, who were referred to the radiology center at Imam Hossein Hospital in Shahroud, was collected. CT scan reports were categorized into three groups based on the radiologist’s interpretation. The BEIR VII model was employed to estimate the risk of radiation-induced cancer.

Results

Among the 561 patients, 299 (53.3%) were males and the average age of the patients was 49.61 ± 18.73 years. Of the CT scans, 408 (72.7%) were reported as normal. The average age of patients with normal, abnormal, and potentially abnormal CT scans was 47.57 ± 19.06, 54.80 ± 16.70, and 58.14 ± 16.60 years, respectively (p-value < 0.001). The average effective dose was 1.89 ± 0.21 mSv, with 1.76 ± 0.11 mSv for males and 2.05 ± 0.29 mSv for females (p-value < 0.001). The average risk of lung cancer was 3.84 ± 1.19 and 9.73 ± 3.27 cases per 100,000 patients for males and females, respectively. The average LAR for all cancer types was 10.30 ± 6.03 cases per 100,000 patients.

Conclusions

This study highlights the critical issue of increased CT scan usage for COVID-19 diagnosis and the potential long-term consequences, especially the risk of cancer incidence. Healthcare policies should be prepared to address this potential rise in cancer incidence and the utilization of CT scans should be restricted to cases where laboratory tests are not readily available or when clinical symptoms are severe.
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Metadata
Title
COVID-19 and cancer risk arising from ionizing radiation exposure through CT scans: a cross-sectional study
Authors
Golshan Mahmoudi
Heidar Toolee
Reza Maskani
Farzaneh Jokar
Milad Mokfi
Ali Hosseinzadeh
Publication date
01-12-2024
Publisher
BioMed Central
Published in
BMC Cancer / Issue 1/2024
Electronic ISSN: 1471-2407
DOI
https://doi.org/10.1186/s12885-024-12050-x

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