Skip to main content
Top
Published in: BMC Pediatrics 1/2022

Open Access 01-12-2022 | Computed Tomography | Case report

A case report of renal calyceal diverticulum with hypertension in children and review of literature

Authors: Yongxiang Zhao, Ruimin Zhang, Ye Yun, Xiangming Wu, Haowei Li, Jun Wang, Wei Wang, Chunmei Jia, Hongcheng Song

Published in: BMC Pediatrics | Issue 1/2022

Login to get access

Abstract

Background

Renal calyx diverticulum refers to a cystic lesion covered with the transitional epithelium in the renal parenchyma. Although there is no clear evidence that calyx diverticulum can cause hypertension, there exists a close association between the two, and there are few related reports. Herein, we reported the case of a child with renal calyx diverticulum complicated with hypertension and summarized the diagnosis and treatment.

Case presentation

Physical examination of the patient, an 11-year-old child, revealed a left renal cyst with hypertension (155/116 mmHg). There were no related symptoms. Routine urine and blood biochemical examinations showed no abnormalities. Imaging revealed left renal cyst compression causing the hypertension. She underwent renal cyst fluid aspiration and injection of a sclerosing agent into the capsule, but her blood pressure increased again 3 days postoperatively. Color Doppler ultrasonography showed that the size of the left renal cyst was the same as that preoperatively. To further confirm the diagnosis, cystoscopic retrograde ureteropyelography was performed to confirm the diagnosis of renal calyx diverticulum. Subsequently, renal calyceal diverticulum resection and calyx neck enlargement were performed. The operation went smoothly and the blood pressure returned to normal postoperatively. No abnormalities were noted at the 7-month postoperative follow-up.

Conclusion

There exists an association between renal calyx diverticulum and hypertension. Therefore, hypertension can be considered a surgical indication for renal calyx diverticulum. Moreover, renal calyceal diverticulum in children can be easily misdiagnosed as a renal cyst. Therefore, it is important to be vigilant to prevent a series of complications, such as postoperative urine leakage, in such cases.
Literature
1.
go back to reference Koopman SG, Fuchs GJ. Intrarenal Stenosis and Stones: Calyceal diverticulum and infundibular Stenosis. In: Ureteroscopy edn: Springer; 2013. p. 407–16. Koopman SG, Fuchs GJ. Intrarenal Stenosis and Stones: Calyceal diverticulum and infundibular Stenosis. In: Ureteroscopy edn: Springer; 2013. p. 407–16.
2.
go back to reference Sahin H, Sarioglu FC, Alaygut D, Akdogan AI, Pekcevik Y. Differentiation of simple renal parenchymal cyst and calyceal diverticulum. Pediatr Int. 2020;62:615–23.CrossRef Sahin H, Sarioglu FC, Alaygut D, Akdogan AI, Pekcevik Y. Differentiation of simple renal parenchymal cyst and calyceal diverticulum. Pediatr Int. 2020;62:615–23.CrossRef
3.
go back to reference Zhang Z, Zhang Y, Wang X, Chen D, Peng N, Chen J, et al. Challenges in the diagnosis of calyceal diverticulum: a report of two cases and review of the literature. J Xray Sci Technol. 2019;27:1155–67.PubMed Zhang Z, Zhang Y, Wang X, Chen D, Peng N, Chen J, et al. Challenges in the diagnosis of calyceal diverticulum: a report of two cases and review of the literature. J Xray Sci Technol. 2019;27:1155–67.PubMed
4.
go back to reference Smyth N, Somani B, Rai B, Aboumarzouk OM. Treatment options for Calyceal diverticula. Curr Urol Rep. 2019;20:37.CrossRef Smyth N, Somani B, Rai B, Aboumarzouk OM. Treatment options for Calyceal diverticula. Curr Urol Rep. 2019;20:37.CrossRef
5.
go back to reference Mitome T, Tabei T, Tsuura Y, Kobayashi K. Squamous cell carcinoma in a Calyceal diverticulum detected by percutaneous Nephroscopic biopsy. Case Rep Oncol Med. 2018;2018:3508537.PubMedPubMedCentral Mitome T, Tabei T, Tsuura Y, Kobayashi K. Squamous cell carcinoma in a Calyceal diverticulum detected by percutaneous Nephroscopic biopsy. Case Rep Oncol Med. 2018;2018:3508537.PubMedPubMedCentral
6.
go back to reference Yamasaki T, Yoshioka T, Imoto M, Aoki H, Fujio K, Uehara S, et al. Rupture of a Calyceal diverticulum secondary to Ureteroscopy: a rare complication. Case Rep Urol. 2018;2018:9285671.PubMedPubMedCentral Yamasaki T, Yoshioka T, Imoto M, Aoki H, Fujio K, Uehara S, et al. Rupture of a Calyceal diverticulum secondary to Ureteroscopy: a rare complication. Case Rep Urol. 2018;2018:9285671.PubMedPubMedCentral
7.
go back to reference Zhang R, Shen W, Li X, Shen J, Tan J, Hao X. A Petal-like Calyceal Diverticulum. Urology. 2015;86:e31–2.CrossRef Zhang R, Shen W, Li X, Shen J, Tan J, Hao X. A Petal-like Calyceal Diverticulum. Urology. 2015;86:e31–2.CrossRef
8.
go back to reference Peng YH, Zhang W, Gao XF, Sun YH. Calyceal diverticulum mimicking simple parapelvic cyst: a case report. Chin Med Sci J. 2015;30:56–8.CrossRef Peng YH, Zhang W, Gao XF, Sun YH. Calyceal diverticulum mimicking simple parapelvic cyst: a case report. Chin Med Sci J. 2015;30:56–8.CrossRef
10.
go back to reference Sripathi V, Mitra A, Padankatti RL, Ganesan T. Robotic treatment of a type 2 calyceal diverticulum in a child: is suture closure and marsupialisation enough for a good outcome? J Robot Surg. 2018;12:727–30.CrossRef Sripathi V, Mitra A, Padankatti RL, Ganesan T. Robotic treatment of a type 2 calyceal diverticulum in a child: is suture closure and marsupialisation enough for a good outcome? J Robot Surg. 2018;12:727–30.CrossRef
11.
go back to reference Pan Y, Chen G, Chen H, Zhu Y, Chen H. The left ureterocele and stone of calyceal diverticulum in the patient with bilateral incomplete duplex kidneys managed by flexible ureteroscopy: a case report and literature review. BMC Urol. 2020;20:35.CrossRef Pan Y, Chen G, Chen H, Zhu Y, Chen H. The left ureterocele and stone of calyceal diverticulum in the patient with bilateral incomplete duplex kidneys managed by flexible ureteroscopy: a case report and literature review. BMC Urol. 2020;20:35.CrossRef
12.
go back to reference Pareek A, Laursen CB, Graumann O. Calyceal diverticulum: a benign imitator of serious pathology. BMJ Case Rep. 2014;2014:bcr2013202301.CrossRef Pareek A, Laursen CB, Graumann O. Calyceal diverticulum: a benign imitator of serious pathology. BMJ Case Rep. 2014;2014:bcr2013202301.CrossRef
13.
go back to reference Ng WM. Retrograde intrarenal surgery in atretic calyceal diverticular stone, a case report. Urol Case Rep. 2019;24:100840.CrossRef Ng WM. Retrograde intrarenal surgery in atretic calyceal diverticular stone, a case report. Urol Case Rep. 2019;24:100840.CrossRef
14.
go back to reference Alwaal A, Azhar RA, Andonian S. Percutaneous holmium laser fulguration of calyceal diverticula. Case Rep Urol. 2012;2012:716786.PubMedPubMedCentral Alwaal A, Azhar RA, Andonian S. Percutaneous holmium laser fulguration of calyceal diverticula. Case Rep Urol. 2012;2012:716786.PubMedPubMedCentral
15.
go back to reference Oh MM, Kim JW, Kim JW, Chae JY, Yoon CY, Park HS, et al. Bacterial sepsis after extracorporeal shock-wave lithotripsy (ESWL) of calyceal diverticular stone. Urolithiasis. 2013;41:95–7.CrossRef Oh MM, Kim JW, Kim JW, Chae JY, Yoon CY, Park HS, et al. Bacterial sepsis after extracorporeal shock-wave lithotripsy (ESWL) of calyceal diverticular stone. Urolithiasis. 2013;41:95–7.CrossRef
16.
go back to reference Nakano T, Kitagawa Y, Izumi K, Ikeda H, Namiki M. Invasive urothelial carcinoma within a calyceal diverticulum associated with renal stones: a case report. Oncol Lett. 2015;10:2439–41.CrossRef Nakano T, Kitagawa Y, Izumi K, Ikeda H, Namiki M. Invasive urothelial carcinoma within a calyceal diverticulum associated with renal stones: a case report. Oncol Lett. 2015;10:2439–41.CrossRef
17.
go back to reference Ferroni MC, Rycyna KJ, Dwyer ME, Schneck FX. Calyceal diverticulum with a large extra-renal extension in a 5-year-old child. Urology. 2015;85:230–2.CrossRef Ferroni MC, Rycyna KJ, Dwyer ME, Schneck FX. Calyceal diverticulum with a large extra-renal extension in a 5-year-old child. Urology. 2015;85:230–2.CrossRef
18.
go back to reference Bombiński P, Warchoł S, Brzewski M, Biejat A, Dudek-Warchoł T, Krzemień G, et al. Calyceal diverticulum of the kidney - diagnostic imaging dilemma in pediatric patients - case report. Pol J Radiol. 2015;80:27–30.CrossRef Bombiński P, Warchoł S, Brzewski M, Biejat A, Dudek-Warchoł T, Krzemień G, et al. Calyceal diverticulum of the kidney - diagnostic imaging dilemma in pediatric patients - case report. Pol J Radiol. 2015;80:27–30.CrossRef
19.
go back to reference Lin CC, Shih BF, Shih SL, Tsai JD. Potential role of Tc-99m DTPA diuretic renal scan in the diagnosis of Calyceal diverticulum in children. Medicine (Baltimore). 2015;94:e985.CrossRef Lin CC, Shih BF, Shih SL, Tsai JD. Potential role of Tc-99m DTPA diuretic renal scan in the diagnosis of Calyceal diverticulum in children. Medicine (Baltimore). 2015;94:e985.CrossRef
20.
go back to reference Alaygut D, Şahin H, Çamlar SA, Soyaltın E, Öncel EP, Alparslan C, et al. Calyceal diverticulum of the kidney in pediatric patients - is it as rare as you might think? J Pediatr Urol. 2020;16:487.e1–6.CrossRef Alaygut D, Şahin H, Çamlar SA, Soyaltın E, Öncel EP, Alparslan C, et al. Calyceal diverticulum of the kidney in pediatric patients - is it as rare as you might think? J Pediatr Urol. 2020;16:487.e1–6.CrossRef
21.
go back to reference Dong B, Ma J, Wang HJ, Wang ZQ. The association of overweight and obesity with blood pressure among Chinese children and adolescents. Biomed Environ Sci. 2013;26:437–44.PubMed Dong B, Ma J, Wang HJ, Wang ZQ. The association of overweight and obesity with blood pressure among Chinese children and adolescents. Biomed Environ Sci. 2013;26:437–44.PubMed
22.
go back to reference Gross AJ, Fisher M. Management of stones in patients with anomalously sited kidneys. Curr Opin Urol. 2006;16:100–5.CrossRef Gross AJ, Fisher M. Management of stones in patients with anomalously sited kidneys. Curr Opin Urol. 2006;16:100–5.CrossRef
23.
go back to reference Yu WW, Zhang DH, He X, Zhang YL, D. LG, Wang XL, Deng G, B. S, Wang YY. Incision and internal drainage treatment of renal cyst and calyceal diverticulum by endoscope. J Clin Urology. 2013;5:337–39+342. Yu WW, Zhang DH, He X, Zhang YL, D. LG, Wang XL, Deng G, B. S, Wang YY. Incision and internal drainage treatment of renal cyst and calyceal diverticulum by endoscope. J Clin Urology. 2013;5:337–39+342.
24.
go back to reference Gandomi B, Bayat A, Kazemei T. Outcomes of septoplasty in young adults: the nasal obstruction Septoplasty effectiveness study. Am J Otolaryngol. 2010;31:189–92.CrossRef Gandomi B, Bayat A, Kazemei T. Outcomes of septoplasty in young adults: the nasal obstruction Septoplasty effectiveness study. Am J Otolaryngol. 2010;31:189–92.CrossRef
25.
go back to reference Kavukcu S, Cakmakci H, Babayigit A. Diagnosis of caliceal diverticulum in two pediatric patients: a comparison of sonography, CT, and urography. J Clin Ultrasound. 2003;31:218–21.CrossRef Kavukcu S, Cakmakci H, Babayigit A. Diagnosis of caliceal diverticulum in two pediatric patients: a comparison of sonography, CT, and urography. J Clin Ultrasound. 2003;31:218–21.CrossRef
26.
go back to reference Long CJ, Weiss DA, Kolon TF, Srinivasan AK, Shukla AR. Pediatric calyceal diverticulum treatment: an experience with endoscopic and laparoscopic approaches. J Pediatr Urol. 2015;11(172):e1–6. Long CJ, Weiss DA, Kolon TF, Srinivasan AK, Shukla AR. Pediatric calyceal diverticulum treatment: an experience with endoscopic and laparoscopic approaches. J Pediatr Urol. 2015;11(172):e1–6.
27.
go back to reference De Naeyer G, Schatteman P, Carpentier P, Mottrie A. 84 robot assisted laparoscopic calyceal diverticulum repair. Eur Urol Suppl. 2010;9:523–4.CrossRef De Naeyer G, Schatteman P, Carpentier P, Mottrie A. 84 robot assisted laparoscopic calyceal diverticulum repair. Eur Urol Suppl. 2010;9:523–4.CrossRef
28.
go back to reference Parkhomenko E, Tran T, Thai J, Blum K, Gupta M. Percutaneous Management of Stone Containing Calyceal Diverticula: associated factors and outcomes. J Urol. 2017;198:864–8.CrossRef Parkhomenko E, Tran T, Thai J, Blum K, Gupta M. Percutaneous Management of Stone Containing Calyceal Diverticula: associated factors and outcomes. J Urol. 2017;198:864–8.CrossRef
29.
go back to reference Gross AJ, Herrmann TR. Management of stones in calyceal diverticulum. Curr Opin Urol. 2007;17:136–40.CrossRef Gross AJ, Herrmann TR. Management of stones in calyceal diverticulum. Curr Opin Urol. 2007;17:136–40.CrossRef
30.
go back to reference Mangray M, Vella JP. Hypertension after kidney transplant. Am J Kidney Dis. 2011;57:331–41.CrossRef Mangray M, Vella JP. Hypertension after kidney transplant. Am J Kidney Dis. 2011;57:331–41.CrossRef
31.
go back to reference Campese VM, Park J. The kidney and hypertension: over 70 years of research. J Nephrol. 2006;19:691–8.PubMed Campese VM, Park J. The kidney and hypertension: over 70 years of research. J Nephrol. 2006;19:691–8.PubMed
32.
go back to reference Malyszko J, Malyszko JS, Mikhailidis DP, Rysz J, Zorawski M, Banach M. Hypertension and kidney disease: is renalase a new player or an innocent bystander? J Hypertens. 2012;30:457–62.CrossRef Malyszko J, Malyszko JS, Mikhailidis DP, Rysz J, Zorawski M, Banach M. Hypertension and kidney disease: is renalase a new player or an innocent bystander? J Hypertens. 2012;30:457–62.CrossRef
33.
go back to reference Desir GV, Peixoto AJ. Renalase in hypertension and kidney disease. Nephrol Dial Transplant. 2014;29:22–8.CrossRef Desir GV, Peixoto AJ. Renalase in hypertension and kidney disease. Nephrol Dial Transplant. 2014;29:22–8.CrossRef
34.
go back to reference Wu Y, Xu J, Velazquez H, Wang P, Li G, Liu D, et al. Renalase deficiency aggravates ischemic myocardial damage. Kidney Int. 2011;79:853–60.CrossRef Wu Y, Xu J, Velazquez H, Wang P, Li G, Liu D, et al. Renalase deficiency aggravates ischemic myocardial damage. Kidney Int. 2011;79:853–60.CrossRef
35.
go back to reference Desir GV. Role of renalase in the regulation of blood pressure and the renal dopamine system. Curr Opin Nephrol Hypertens. 2011;20:31–6.CrossRef Desir GV. Role of renalase in the regulation of blood pressure and the renal dopamine system. Curr Opin Nephrol Hypertens. 2011;20:31–6.CrossRef
36.
go back to reference Malyszko J, Malyszko JS, Rysz J, Mysliwiec M, Tesar V, Levin-Iaina N, et al. Renalase, hypertension, and kidney - the discussion continues. Angiology. 2013;64:181–7.CrossRef Malyszko J, Malyszko JS, Rysz J, Mysliwiec M, Tesar V, Levin-Iaina N, et al. Renalase, hypertension, and kidney - the discussion continues. Angiology. 2013;64:181–7.CrossRef
Metadata
Title
A case report of renal calyceal diverticulum with hypertension in children and review of literature
Authors
Yongxiang Zhao
Ruimin Zhang
Ye Yun
Xiangming Wu
Haowei Li
Jun Wang
Wei Wang
Chunmei Jia
Hongcheng Song
Publication date
01-12-2022
Publisher
BioMed Central
Published in
BMC Pediatrics / Issue 1/2022
Electronic ISSN: 1471-2431
DOI
https://doi.org/10.1186/s12887-021-03081-5

Other articles of this Issue 1/2022

BMC Pediatrics 1/2022 Go to the issue