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Archives of Virology
Published in: Archives of Virology 6/2015

01-06-2015 | Brief Report

Coinfection with multiple strains of bovine papular stomatitis virus

Authors: Tao Huang, Edan R. Tulman, Diego G. Diel, Sushil Khatiwada, Will Sims, John F. Edwards, Xintian Wen, Gerald F. Kutish, Daniel L. Rock, Gustavo Delhon

Published in: Archives of Virology | Issue 6/2015

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Abstract

Bovine papular stomatitis virus (BPSV) infects cattle and, occupationally, humans. Prevalent subclinical infections, frequent reinfections, and virus persistence in healthy animals compound a poorly understood, but likely complex, scenario of BPSV perpetuation and transmission in nature. Here, we report the isolation of multiple BPSV strains coinfecting a single animal. Whole-genome analysis of isolated BPSV strains revealed genomic variability likely affecting virus virulence and infectivity. Further, incongruent phylogenetic relationships between viruses suggested genomic recombination. These results have significant implications for parapoxvirus infection biology and virus evolution in nature.
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Metadata
Title
Coinfection with multiple strains of bovine papular stomatitis virus
Authors
Tao Huang
Edan R. Tulman
Diego G. Diel
Sushil Khatiwada
Will Sims
John F. Edwards
Xintian Wen
Gerald F. Kutish
Daniel L. Rock
Gustavo Delhon
Publication date
01-06-2015
Publisher
Springer Vienna
Published in
Archives of Virology / Issue 6/2015
Print ISSN: 0304-8608
Electronic ISSN: 1432-8798
DOI
https://doi.org/10.1007/s00705-015-2394-2

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