Issue 5/2020
Content (10 Articles)
Clinical Pharmacokinetics of Upadacitinib: Review of Data Relevant to the Rheumatoid Arthritis Indication
Mohamed-Eslam F. Mohamed, Ben Klünder, Ahmed A. Othman
Pharmacokinetics and Pharmacodynamics of Approved and Investigational P2Y12 Receptor Antagonists
Uta Schilling, Jasper Dingemanse, Mike Ufer
Clinical Pharmacokinetics and Pharmacodynamics of Imipenem–Cilastatin/Relebactam Combination Therapy
Matthew W. McCarthy
Exposure–Response Relationships for the Efficacy and Safety of Risankizumab in Japanese Subjects with Psoriasis
Ahmed A. Suleiman, Amit Khatri, Rajneet K. Oberoi, Ahmed A. Othman
A Population Pharmacokinetic Model Does Not Predict the Optimal Starting Dose of Tacrolimus in Pediatric Renal Transplant Recipients in a Prospective Study: Lessons Learned and Model Improvement
Louise M. Andrews, Brenda C. M. de Winter, Elisabeth A. M. Cornelissen, Huib de Jong, Dennis A. Hesselink, Michiel F. Schreuder, Roger J. M. Brüggemann, Teun van Gelder, Karlien Cransberg
Favorable Pharmacokinetic Characteristics of Extended-Half-Life Recombinant Factor VIII BAY 94-9027 Enable Robust Individual Profiling Using a Population Pharmacokinetic Approach
Alexander Solms, Alfonso Iorio, Maurice J. Ahsman, Peter Vis, Anita Shah, Erik Berntorp, Dirk Garmann
Quantitative Assessment of Elagolix Enzyme-Transporter Interplay and Drug–Drug Interactions Using Physiologically Based Pharmacokinetic Modeling
Manoj S. Chiney, Juki Ng, John P. Gibbs, Mohamad Shebley
Fetal Physiologically Based Pharmacokinetic Models: Systems Information on Fetal Blood Components and Binding Proteins
Khaled Abduljalil, Masoud Jamei, Trevor N. Johnson
Midazolam Pharmacokinetics in Obese and Non-obese Children and Adolescents
Christina Gade, Eva Sverrisdóttir, Kim Dalhoff, Jesper Sonne, Mia Østergaard Johansen, Hanne Rolighed Christensen, Jürgen Burhenne, Gerd Mikus, Jens Christian Holm, Trine Meldgaard Lund, Helle Holst
Comment on “Levothyrox® New and Old Formulations: Are They Switchable for Millions of Patients?”
Rudolf Hoermann, John E. M. Midgley, Rolf Larisch, Johannes W. Dietrich