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Clinical Pharmacokinetics

Issue 2/2023

Content (11 Articles)

Pharmacodynamics Review Article

Pharmacokinetic Alterations Associated with Critical Illness

Diana Morales Castro, Linda Dresser, John Granton, Eddy Fan

Open Access Ampicillin Systematic Review

Pharmacokinetics and Target Attainment of Antimicrobial Drugs Throughout Pregnancy: Part I—Penicillins

M. R. Hesse, J. R. Prins, M. N. Lub-de Hooge, H. L. J. Winter, J. G. W. Kosterink, D. J. Touw, Paola Mian

Open Access Glimepiride Original Research Article

Physiologically Based Pharmacokinetic Modelling to Identify Physiological and Drug Parameters Driving Pharmacokinetics in Obese Individuals

Mattia Berton, Sara Bettonte, Felix Stader, Manuel Battegay, Catia Marzolini

Pharmacokinetics Original Research Article

Low and Highly Variable Exposure to Prophylactic LMWH Nadroparin in Critically Ill Patients: Back to the Drawing Board for Prophylactic Dosing?

Jeroen Diepstraten, Anne van Rongen, Marianne P. Zijlstra, Marieke J. H. A. Kruip, Pim L. J. van der Heiden, Rob ter Heine

Chronic Kidney Disease Original Research Article

Evaluation of Renal Impairment Influence on Metabolic Drug Clearance using a Modelling Approach

Vianney Tuloup, Sylvain Goutelle, Michel Tod, Laurent Bourguignon

Open Access Pharmacodynamics Original Research Article

Evaluation of the Influence of Sildenafil on the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Vericiguat in Healthy Adults

Michael Boettcher, Bettina Nowotny, Robert Krausche, Corina Becker

Pharmacokinetics Original Research Article

Population Pharmacokinetics of Levosimendan and its Metabolites in Critically Ill Neonates and Children Supported or Not by Extracorporeal Membrane Oxygenation

Pierre Bourgoin, Jules Lecomte, Mehdi Oualha, Lionel Berthomieu, Tony Pereira, Emeline Davril, Fabien Lamoureux, Nicolas Joram, Alexis Chenouard, Thomas Duflot

Correction to: Population Pharmacokinetics of Levosimendan and its Metabolites in Critically Ill Neonates and Children Supported or Not by Extracorporeal Membrane Oxygenation

Pierre Bourgoin, Jules Lecomte, Mehdi Oualha, Lionel Berthomieu, Tony Pereira, Emeline Davril, Fabien Lamoureux, Nicolas Joram, Alexis Chenouard, Thomas Duflot