Skip to main content
Top
Published in: BMC Oral Health 1/2023

Open Access 01-12-2023 | Cleft Lip and Palate | Research

Effects of Alt-RAMEC protocol with facemask therapy in cleft lip palate patients in a sample of Pakistani population

Authors: Qurrat-ul-ain Sami, Batool Ali, Waqas Ahmed Farooqui

Published in: BMC Oral Health | Issue 1/2023

Login to get access

Abstract

Objective

The objective of the study is to evaluate the skeletal, dentoalveolar and soft tissue changes before and after treatment with Alt-RAMEC protocol and protraction headgear in comparison to the controls.

Material and methods

A quasi experimental study was conducted in the orthodontic department on 60 patients of cleft lip and palate. These patients were divided into two groups. Group I was the Alt-RAMEC group that underwent Alt-RAMEC protocol followed by facemask therapy while group II was the control group that underwent RME and facemask therapy. Total treatment time in both the groups was approximately 6 to 7 months. Mean and standard deviation was calculated for all the quantitative variables. Pre and post treatment changes between treatment and control groups were made using paired t-test. Intergroup comparison between treatment and control group was analyzed using independent t-test. Significance for all tests was predetermined at a P-value of  ≤ 0.05.

Results

The Alt-RAMEC group showed significant forward movement of maxilla and improvement in the maxillary base. A remarkable improvement in SNA was seen. The overall outcome was better maxillo-mandibular relationship as shown by positive ANB values and angle of convexity. More effect on maxilla and least effect on mandible was notified with Alt-RAMEC protocol and facemask therapy. Improvement in transverse relationship was also evident in the Alt-RAMEC group.

Conclusion

Alt-RAMEC protocol in combination with protraction headgear is a better alternative to treat cleft lip and palate patients in comparison to the conventional protocol.
Literature
1.
go back to reference Singh S, Batra P, Raghavan S, Sharma K, Srivastava A. Evaluation of Alt-RAMEC with facemask in patients with unilateral cleft lip and palate (UCLP) using cone beam computed tomography (CBCT) and finite element modeling- a clinical prospective study. Cleft Palate Craniofac J. 2022;59(2):166–76.CrossRefPubMed Singh S, Batra P, Raghavan S, Sharma K, Srivastava A. Evaluation of Alt-RAMEC with facemask in patients with unilateral cleft lip and palate (UCLP) using cone beam computed tomography (CBCT) and finite element modeling- a clinical prospective study. Cleft Palate Craniofac J. 2022;59(2):166–76.CrossRefPubMed
2.
go back to reference Sadiq H, Ijaz R, Ayub A. Patterns of orofacial clefts and associated risk factors in Pakistan: an institutional experience. J Cleft Lip Palate and Craniofacial Anomalies. 2022;9(2):145–50.CrossRef Sadiq H, Ijaz R, Ayub A. Patterns of orofacial clefts and associated risk factors in Pakistan: an institutional experience. J Cleft Lip Palate and Craniofacial Anomalies. 2022;9(2):145–50.CrossRef
3.
go back to reference Alam MK, Alfawzan AA, Haque S, Mok PL, Marya A, Venugopal A, et al. Sagittal jaw relationship of different types of cleft and non-cleft individuals. Front Pediatr. 2021;9:651951.CrossRefPubMedPubMedCentral Alam MK, Alfawzan AA, Haque S, Mok PL, Marya A, Venugopal A, et al. Sagittal jaw relationship of different types of cleft and non-cleft individuals. Front Pediatr. 2021;9:651951.CrossRefPubMedPubMedCentral
4.
go back to reference Sharif F, Mahmood F, Azhar MJ, Asif A, Zahid M, Muhammad N, et al. Incidence and management of cleft lip and palate in Pakistan. J Pak Med Assoc. 2019;69(5):632–9.PubMed Sharif F, Mahmood F, Azhar MJ, Asif A, Zahid M, Muhammad N, et al. Incidence and management of cleft lip and palate in Pakistan. J Pak Med Assoc. 2019;69(5):632–9.PubMed
5.
go back to reference Wu Z, Zhang X, Li Z, Liu Y, Jin H, Chen Q, et al. A Bayesian network meta-analysis of orthopaedic treatment in Class III malocclusion: Maxillary protraction with skeletal anchorage or a rapid maxillary expander. Orthod Craniofac Res. 2020;23(1):1–15.CrossRefPubMed Wu Z, Zhang X, Li Z, Liu Y, Jin H, Chen Q, et al. A Bayesian network meta-analysis of orthopaedic treatment in Class III malocclusion: Maxillary protraction with skeletal anchorage or a rapid maxillary expander. Orthod Craniofac Res. 2020;23(1):1–15.CrossRefPubMed
6.
go back to reference Meazzini MC, Torre C, Cappello A, Tintinelli R, De Ponti E, Mazzoleni F. Long-term follow-up of late maxillary orthopedic advancement with the Liou-Alternate rapid maxillary expansion-constriction technique in patients with skeletal Class III malocclusion. Am J Orthod Dentofac Orthop. 2021;160(2):221–30.CrossRef Meazzini MC, Torre C, Cappello A, Tintinelli R, De Ponti E, Mazzoleni F. Long-term follow-up of late maxillary orthopedic advancement with the Liou-Alternate rapid maxillary expansion-constriction technique in patients with skeletal Class III malocclusion. Am J Orthod Dentofac Orthop. 2021;160(2):221–30.CrossRef
7.
go back to reference Liou EJ. Effective maxillary orthopedic protraction for growing Class III patients: a clinical application simulates distraction osteogenesis. Prog Orthod. 2005;6(2):154–71.PubMed Liou EJ. Effective maxillary orthopedic protraction for growing Class III patients: a clinical application simulates distraction osteogenesis. Prog Orthod. 2005;6(2):154–71.PubMed
8.
go back to reference Büyükçavuş MH. Alternate rapid maxillary expansion and constriction (Alt-RAMEC) protocol: a comprehensive literature review. Turk J Orthod. 2019;32(1):47–51.CrossRefPubMedPubMedCentral Büyükçavuş MH. Alternate rapid maxillary expansion and constriction (Alt-RAMEC) protocol: a comprehensive literature review. Turk J Orthod. 2019;32(1):47–51.CrossRefPubMedPubMedCentral
9.
go back to reference Wang YC, Chang PM, Liou EJ. Opening of circumaxillary sutures by alternate rapid maxillary expansions and constrictions. Angle Orthod. 2009;79(2):230–4.CrossRefPubMed Wang YC, Chang PM, Liou EJ. Opening of circumaxillary sutures by alternate rapid maxillary expansions and constrictions. Angle Orthod. 2009;79(2):230–4.CrossRefPubMed
10.
go back to reference da Luz VG, de Menezes LM, de Lima EM, Rizzatto S. Dentoskeletal effects of maxillary protraction in cleft patients with repetitive weekly protocol of alternate rapid maxillary expansions and constrictions. Cleft Palate Craniofac J. 2009;46(4):391–8.CrossRef da Luz VG, de Menezes LM, de Lima EM, Rizzatto S. Dentoskeletal effects of maxillary protraction in cleft patients with repetitive weekly protocol of alternate rapid maxillary expansions and constrictions. Cleft Palate Craniofac J. 2009;46(4):391–8.CrossRef
11.
go back to reference Baccetti T, Franchi L, McNamara JA. The cervical vertebral maturation (CVM) method for the assessment of optimal treatment timing in dentofacial orthopedics. Semin Orthod. 2005;11(3):119–29.CrossRef Baccetti T, Franchi L, McNamara JA. The cervical vertebral maturation (CVM) method for the assessment of optimal treatment timing in dentofacial orthopedics. Semin Orthod. 2005;11(3):119–29.CrossRef
12.
go back to reference Fischer B, Masucci C, Ruellas A, Cevidanes L, Giuntini V, Nieri M, et al. Three-dimensional evaluation of the maxillary effects of two orthopaedic protocols for the treatment of Class III malocclusion: a prospective study. Orthod Craniofac Res. 2018;21(4):248–57.CrossRefPubMed Fischer B, Masucci C, Ruellas A, Cevidanes L, Giuntini V, Nieri M, et al. Three-dimensional evaluation of the maxillary effects of two orthopaedic protocols for the treatment of Class III malocclusion: a prospective study. Orthod Craniofac Res. 2018;21(4):248–57.CrossRefPubMed
13.
go back to reference Al-Mozany SA, Dalci O, Almuzian M, Gonzalez C, Tarraf NE, Ali DM. A novel method for treatment of Class III malocclusion in growing patients. Prog Orthod. 2017;18(1):40.CrossRefPubMedPubMedCentral Al-Mozany SA, Dalci O, Almuzian M, Gonzalez C, Tarraf NE, Ali DM. A novel method for treatment of Class III malocclusion in growing patients. Prog Orthod. 2017;18(1):40.CrossRefPubMedPubMedCentral
14.
go back to reference Wilmes B, Ngan P, Liou E, Franchi L, Drescher D. Early Class III facemask treatment with the hybrid hyrax and Alt-RAMEC protocol. J Clin Orthod. 2014;48:84–93.PubMed Wilmes B, Ngan P, Liou E, Franchi L, Drescher D. Early Class III facemask treatment with the hybrid hyrax and Alt-RAMEC protocol. J Clin Orthod. 2014;48:84–93.PubMed
15.
go back to reference Canturk BH, Celikoglu M. Comparison of the effects of face mask treatment started simultaneously and after the completion of the alternate rapid maxillary expansion and constriction procedure. Angle Orthod. 2014;85(2):284–91.CrossRefPubMedPubMedCentral Canturk BH, Celikoglu M. Comparison of the effects of face mask treatment started simultaneously and after the completion of the alternate rapid maxillary expansion and constriction procedure. Angle Orthod. 2014;85(2):284–91.CrossRefPubMedPubMedCentral
16.
go back to reference Meazzini MC, Zappia LB, Tortora C, Autelitano L, Tintinelli R. Short- and long-term effects of late maxillary advancement with the Liou-Alt-RAMEC protocol in unilateral cleft lip and palate. Cleft Palate Craniofac J. 2019;56(2):159–67.CrossRefPubMed Meazzini MC, Zappia LB, Tortora C, Autelitano L, Tintinelli R. Short- and long-term effects of late maxillary advancement with the Liou-Alt-RAMEC protocol in unilateral cleft lip and palate. Cleft Palate Craniofac J. 2019;56(2):159–67.CrossRefPubMed
17.
go back to reference Onem Ozbilen E, Yilmaz HN, Kucukkeles N. Comparison of the effects of rapid maxillary expansion and alternate rapid maxillary expansion and constriction protocols followed by facemask therapy. Korean J Orthod. 2019;49(1):49–58.CrossRefPubMed Onem Ozbilen E, Yilmaz HN, Kucukkeles N. Comparison of the effects of rapid maxillary expansion and alternate rapid maxillary expansion and constriction protocols followed by facemask therapy. Korean J Orthod. 2019;49(1):49–58.CrossRefPubMed
18.
go back to reference Almuzian M, McConnell E, Darendeliler MA, Alharbi F, Mohammed H. The effectiveness of alternating rapid maxillary expansion and constriction combined with maxillary protraction in the treatment of patients with a class III malocclusion: a systematic review and meta-analysis. J Orthod. 2018;45(4):250–9.CrossRefPubMed Almuzian M, McConnell E, Darendeliler MA, Alharbi F, Mohammed H. The effectiveness of alternating rapid maxillary expansion and constriction combined with maxillary protraction in the treatment of patients with a class III malocclusion: a systematic review and meta-analysis. J Orthod. 2018;45(4):250–9.CrossRefPubMed
19.
go back to reference Dogan E, Seckin O. Maxillary protraction in patients with unilateral cleft lip and palate: Evaluation of soft and hard tissues using the Alt-RAMEC protocol. J OrofacOrthop. 2020;81(3):209–19. Dogan E, Seckin O. Maxillary protraction in patients with unilateral cleft lip and palate: Evaluation of soft and hard tissues using the Alt-RAMEC protocol. J OrofacOrthop. 2020;81(3):209–19.
20.
go back to reference Halicioglu K, Yavuz I, Ceylan I, Erdem A. Effects of face mask treatment with and without rapid maxillary expansion in young adult subjects. Angle Orthod. 2014;84(5):853–61.CrossRefPubMedPubMedCentral Halicioglu K, Yavuz I, Ceylan I, Erdem A. Effects of face mask treatment with and without rapid maxillary expansion in young adult subjects. Angle Orthod. 2014;84(5):853–61.CrossRefPubMedPubMedCentral
21.
go back to reference Liu W, Zhou Y, Wang X, Liu D, Zhou S. Effect of maxillary protraction with alternating rapid palatal expansion and constriction vs expansion alone in maxillary retrusive patients: a single-center, randomized controlled trial. Am J Orthod Dentofac Orthop. 2015;148(4):641–51.CrossRef Liu W, Zhou Y, Wang X, Liu D, Zhou S. Effect of maxillary protraction with alternating rapid palatal expansion and constriction vs expansion alone in maxillary retrusive patients: a single-center, randomized controlled trial. Am J Orthod Dentofac Orthop. 2015;148(4):641–51.CrossRef
22.
go back to reference Kaya D, Kocadereli I, Kan B, Tasar F. Effects of facemask treatment anchored with miniplates after alternate rapid maxillary expansions and constrictions; a pilot study. Angle Orthod. 2011;81(4):639–46.CrossRefPubMedPubMedCentral Kaya D, Kocadereli I, Kan B, Tasar F. Effects of facemask treatment anchored with miniplates after alternate rapid maxillary expansions and constrictions; a pilot study. Angle Orthod. 2011;81(4):639–46.CrossRefPubMedPubMedCentral
23.
go back to reference Yatabe M, Garib DG, Faco RAS, de Clerck H, Janson G, Nguyen T, et al. Bone-anchored maxillary protraction therapy in patients with unilateral complete cleft lip and palate: 3-dimensional assessment of maxillary effects. Am J Orthod Dentofac Orthop. 2017;152(3):327–35.CrossRef Yatabe M, Garib DG, Faco RAS, de Clerck H, Janson G, Nguyen T, et al. Bone-anchored maxillary protraction therapy in patients with unilateral complete cleft lip and palate: 3-dimensional assessment of maxillary effects. Am J Orthod Dentofac Orthop. 2017;152(3):327–35.CrossRef
24.
go back to reference Garib D, Lauris RDCMC, Calil LR, Alves ACDM, Janson G, De Almeida AM, et al. Dentoskeletal outcomes of a rapid maxillary expander with differential opening in patients with bilateral cleft lip and palate: a prospective clinical trial. Am J Orthod Dentofac Orthop. 2016;150(4):564–74.CrossRef Garib D, Lauris RDCMC, Calil LR, Alves ACDM, Janson G, De Almeida AM, et al. Dentoskeletal outcomes of a rapid maxillary expander with differential opening in patients with bilateral cleft lip and palate: a prospective clinical trial. Am J Orthod Dentofac Orthop. 2016;150(4):564–74.CrossRef
25.
go back to reference Büyükçavuş MH. Comparison of transversal effects of different expansion protocols: Alt-RAMEC versus RME. South Eur J Orthod Dentofac Res. 2020;7(2):43–8. Büyükçavuş MH. Comparison of transversal effects of different expansion protocols: Alt-RAMEC versus RME. South Eur J Orthod Dentofac Res. 2020;7(2):43–8.
26.
go back to reference Rota E, Ferrari M, Maddalone M. Dentofacial effects of modified Alt-RAMEC protocol combined with the facial mask for treatment of preadolescent caucasian Class III Patients. Int J Clin Pediatr Dent. 2019;12(3):222–8.CrossRefPubMedPubMedCentral Rota E, Ferrari M, Maddalone M. Dentofacial effects of modified Alt-RAMEC protocol combined with the facial mask for treatment of preadolescent caucasian Class III Patients. Int J Clin Pediatr Dent. 2019;12(3):222–8.CrossRefPubMedPubMedCentral
27.
go back to reference Liu Y, Hou R, Jin H, Zhang X, Wu Z, Li Z, et al. Relative effectiveness of facemask therapy with alternate maxillary expansion and constriction in the early treatment of Class III malocclusion. Am J Orthod Dentofac Orthop. 2021;159(3):321–32.CrossRef Liu Y, Hou R, Jin H, Zhang X, Wu Z, Li Z, et al. Relative effectiveness of facemask therapy with alternate maxillary expansion and constriction in the early treatment of Class III malocclusion. Am J Orthod Dentofac Orthop. 2021;159(3):321–32.CrossRef
28.
go back to reference Yilmaz BS, Kucukkeles N. Skeletal, soft tissue, and airway changes following the alternate maxillary expansions and constrictions protocol. Angle Orthod. 2014;84(5):868–77.PubMed Yilmaz BS, Kucukkeles N. Skeletal, soft tissue, and airway changes following the alternate maxillary expansions and constrictions protocol. Angle Orthod. 2014;84(5):868–77.PubMed
29.
go back to reference Isci D, Turk T, Elekdag-Turk S. Activation-deactivation rapid palatal expansion and reverse headgear in Class III cases. Eur J Orthod. 2010;32(6):706–15.CrossRefPubMed Isci D, Turk T, Elekdag-Turk S. Activation-deactivation rapid palatal expansion and reverse headgear in Class III cases. Eur J Orthod. 2010;32(6):706–15.CrossRefPubMed
30.
go back to reference Pithon MM, Santos NL, Santos CR, Baião FC, Pinheiro MC, Matos MN, et al. Is alternate rapid maxillary expansion and constriction an effective protocol in the treatment of Class III malocclusion? A systematic review. Dental Press J Orthod. 2016;21(6):34–42.CrossRefPubMedPubMedCentral Pithon MM, Santos NL, Santos CR, Baião FC, Pinheiro MC, Matos MN, et al. Is alternate rapid maxillary expansion and constriction an effective protocol in the treatment of Class III malocclusion? A systematic review. Dental Press J Orthod. 2016;21(6):34–42.CrossRefPubMedPubMedCentral
31.
go back to reference Celikoglu M, Oktay H. Effects of maxillary protraction for early correction of class III malocclusion. Eur J Orthod. 2014;36(1):86–92.CrossRefPubMed Celikoglu M, Oktay H. Effects of maxillary protraction for early correction of class III malocclusion. Eur J Orthod. 2014;36(1):86–92.CrossRefPubMed
Metadata
Title
Effects of Alt-RAMEC protocol with facemask therapy in cleft lip palate patients in a sample of Pakistani population
Authors
Qurrat-ul-ain Sami
Batool Ali
Waqas Ahmed Farooqui
Publication date
01-12-2023
Publisher
BioMed Central
Published in
BMC Oral Health / Issue 1/2023
Electronic ISSN: 1472-6831
DOI
https://doi.org/10.1186/s12903-023-03093-w

Other articles of this Issue 1/2023

BMC Oral Health 1/2023 Go to the issue