Published in:
Open Access
29-01-2024 | Cholangiocarcinoma | short review
Innovative therapeutic concepts for biliary tumors
Author:
Dr. Angela Djanani
Published in:
memo - Magazine of European Medical Oncology
|
Issue 1/2024
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Summary
In recent years there have been significant changes in the treatment of bile duct carcinoma. Immunotherapy has been included in first-line treatment for about a year now (IO + cisplatin/gemcitabine). Cholangiocarcinomas are genetically very heterogeneous and several new targets have been identified in recent years. These play an important role, especially in second-line treatment. This review aims to highlight the key milestones of current treatment with a focus on targeted therapy options. Especially, current data on therapeutic options such as FGFR‑2, NTRK, IDH‑1, BRAF, HER‑2 are reported.