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Published in: Pediatric Cardiology 7/2010

01-10-2010 | Case Report

Case Report of a 2-Year-Old Boy With Takayasu’s Arteritis: An Atypical, Severe Presentation of a Rare Disease

Authors: Darren P. Berman, Alan B. Lewis, Grace C. Kung

Published in: Pediatric Cardiology | Issue 7/2010

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Abstract

Takayasu’s arteritis is a granulomatous giant-cell arteritis of the aorta and its major branches. It primarily affects East Asian women in their second or third decade of life but is well known to affect all ethnicities across the world. Given its systemic nature, Takayasu’s arteritis has multiorgan involvement, with the majority of disease morbidity related to the cardiovascular, central nervous, and renal systems. This report describes an unusual presentation of Takayasu’s arteritis in a 2½-year-old boy. This is the first report in the literature describing the presence of both severe aortic regurgitation and diffuse coronary artery involvement in a patient so young.
Literature
1.
go back to reference Amano J, Suzuki A (1991) Coronary artery involvement in Takayasu’s arteritis: collective review and guideline for surgical treatment. J Thorac Cardiovasc Surg 102:554–560PubMed Amano J, Suzuki A (1991) Coronary artery involvement in Takayasu’s arteritis: collective review and guideline for surgical treatment. J Thorac Cardiovasc Surg 102:554–560PubMed
2.
go back to reference Braunwald E, Zipes DP, Libby P (2001) Heart disease: a textbook of cardiovascular medicine, 6th edn. WB Saunders, Philadelphia, PA, pp 2200–2202 Braunwald E, Zipes DP, Libby P (2001) Heart disease: a textbook of cardiovascular medicine, 6th edn. WB Saunders, Philadelphia, PA, pp 2200–2202
3.
go back to reference Fadi S, Robert PG, Gregory RG (2009) Takayasu arteritis in a young woman. A 4-year case history. Tex Heart Inst J 36:470–474 Fadi S, Robert PG, Gregory RG (2009) Takayasu arteritis in a young woman. A 4-year case history. Tex Heart Inst J 36:470–474
4.
go back to reference Hashimoto Y, Tanaka M, Hata A, Kakuta T, Maruyama Y, Numano F (1996) Four years follow-up study in patients with Takayasu arteritis and severe aortic regurgitation: assessment by echocardiography. Int J Cardiol 54(Suppl):S173–S176CrossRefPubMed Hashimoto Y, Tanaka M, Hata A, Kakuta T, Maruyama Y, Numano F (1996) Four years follow-up study in patients with Takayasu arteritis and severe aortic regurgitation: assessment by echocardiography. Int J Cardiol 54(Suppl):S173–S176CrossRefPubMed
5.
go back to reference Ishikawa K, Maetani S (1994) Long-term outcome for 120 Japanese patients with Takayasu’s disease: clinical and statistical analyses of related prognostic factors. Circulation 90:1855–1860PubMed Ishikawa K, Maetani S (1994) Long-term outcome for 120 Japanese patients with Takayasu’s disease: clinical and statistical analyses of related prognostic factors. Circulation 90:1855–1860PubMed
6.
go back to reference Johnston SL, Lock RJ, Gompels MM (2002) Takayasu arteritis: a review. J Clin Pathol 55:481–486PubMed Johnston SL, Lock RJ, Gompels MM (2002) Takayasu arteritis: a review. J Clin Pathol 55:481–486PubMed
7.
go back to reference Kerr GS, Hallahan CW, Giordano J, Leavitt RY, Fauci AS, Rottem M, Hoffman GS (1994) Takayasu arteritis. Ann Intern Med 120:919–929PubMed Kerr GS, Hallahan CW, Giordano J, Leavitt RY, Fauci AS, Rottem M, Hoffman GS (1994) Takayasu arteritis. Ann Intern Med 120:919–929PubMed
8.
go back to reference Lupi-Herrera E, Sanchez-Torres G, Marcushamer J, Mispireta J, Horwitz S, Vela JE (1977) Takayasu’s arteritis: clinical study of 107 cases. Am Heart J 93:94–103CrossRefPubMed Lupi-Herrera E, Sanchez-Torres G, Marcushamer J, Mispireta J, Horwitz S, Vela JE (1977) Takayasu’s arteritis: clinical study of 107 cases. Am Heart J 93:94–103CrossRefPubMed
9.
go back to reference Maksimowicz-McKinnon K, Clark TM, Hoffman GS (2007) Limitations of therapy and a guarded prognosis in an American cohort of Takayasu arteritis patients. Arthritis Rheum 56:1000–1009CrossRefPubMed Maksimowicz-McKinnon K, Clark TM, Hoffman GS (2007) Limitations of therapy and a guarded prognosis in an American cohort of Takayasu arteritis patients. Arthritis Rheum 56:1000–1009CrossRefPubMed
10.
go back to reference Nakao K, Ikeda M, Kimata S, Niitani H, Niyahara M (1967) Takayasu’s arteritis: clinical report of eighty-four cases and immunological studies of seven cases. Circulation 35:1141–1155PubMed Nakao K, Ikeda M, Kimata S, Niitani H, Niyahara M (1967) Takayasu’s arteritis: clinical report of eighty-four cases and immunological studies of seven cases. Circulation 35:1141–1155PubMed
11.
go back to reference Numano F, Kakuta T (1996) Takayasu arteritis: five doctors in the history of Takayasu arteritis. Int J Cardiol 54(Suppl):S1–S10PubMed Numano F, Kakuta T (1996) Takayasu arteritis: five doctors in the history of Takayasu arteritis. Int J Cardiol 54(Suppl):S1–S10PubMed
12.
go back to reference Petrovic-Rackov L, Pejnovic N, Jevtic M, Damjanov N (2009) Longitudinal study of 16 patients with Takayasu’s arteritis: clinical features and therapeutic management. Clin Rheumatol 28:179–185CrossRefPubMed Petrovic-Rackov L, Pejnovic N, Jevtic M, Damjanov N (2009) Longitudinal study of 16 patients with Takayasu’s arteritis: clinical features and therapeutic management. Clin Rheumatol 28:179–185CrossRefPubMed
13.
go back to reference Ravelli A, Pedroni E, Perrone S, Tramarin R, Martini A, Burgio GR (1999) Aortic valve regurgitation as the presenting sign of Takayasu arteritis. Eur J Pediatr 158:281–283CrossRefPubMed Ravelli A, Pedroni E, Perrone S, Tramarin R, Martini A, Burgio GR (1999) Aortic valve regurgitation as the presenting sign of Takayasu arteritis. Eur J Pediatr 158:281–283CrossRefPubMed
14.
go back to reference Subramanyan R, Joy J, Balakrishnan KG (1989) Natural history of aortoarteritis (Takayasu’s disease). Circulation 80:429–437PubMed Subramanyan R, Joy J, Balakrishnan KG (1989) Natural history of aortoarteritis (Takayasu’s disease). Circulation 80:429–437PubMed
15.
go back to reference Takayasu M (1908) A case with peculiar changes of the central retinal vessels. Acta Societatis Ophthalmologicae Japonicae Tokyo 12:554 Takayasu M (1908) A case with peculiar changes of the central retinal vessels. Acta Societatis Ophthalmologicae Japonicae Tokyo 12:554
16.
go back to reference Zheng D, Fan D, Liu L (1992) Takayasu arteritis in China: a report of 530 cases. Heart Vessels Suppl 7:32–36CrossRefPubMed Zheng D, Fan D, Liu L (1992) Takayasu arteritis in China: a report of 530 cases. Heart Vessels Suppl 7:32–36CrossRefPubMed
Metadata
Title
Case Report of a 2-Year-Old Boy With Takayasu’s Arteritis: An Atypical, Severe Presentation of a Rare Disease
Authors
Darren P. Berman
Alan B. Lewis
Grace C. Kung
Publication date
01-10-2010
Publisher
Springer-Verlag
Published in
Pediatric Cardiology / Issue 7/2010
Print ISSN: 0172-0643
Electronic ISSN: 1432-1971
DOI
https://doi.org/10.1007/s00246-010-9742-5

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