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Cardiovascular Diabetology

Issue 1/2018

Content (161 Articles)

Open Access Commentary

Asymmetric dimethylarginine (ADMA), symmetric dimethylarginine (SDMA) and homoarginine (hArg): the ADMA, SDMA and hArg paradoxes

Dimitrios Tsikas, Alexander Bollenbach, Erik Hanff, Arslan Arinc Kayacelebi

Open Access Original investigation

Linagliptin and cardiovascular outcomes in type 2 diabetes after acute coronary syndrome or acute ischemic stroke

Yan-Rong Li, Sung-Sheng Tsai, Dong-Yi Chen, Szu-Tah Chen, Jui-Hung Sun, Hung-Yu Chang, Miaw-Jene Liou, Tien-Hsing Chen

Open Access Commentary

Body mass index, type 2 diabetes, and left ventricular function

Katrine Dina Musaeus, Manan Pareek

Open Access Original investigation

Evaluation of the impact of glycemic status on the progression of coronary artery calcification in asymptomatic individuals

Ki-Bum Won, Donghee Han, Ji Hyun Lee, Sang-Eun Lee, Ji Min Sung, Su-Yeon Choi, Eun Ju Chun, Sung Hak Park, Hae-Won Han, Jidong Sung, Hae Ok Jung, Hyuk-Jae Chang

Open Access Original investigation

SGLT-2-inhibition with dapagliflozin reduces tissue sodium content: a randomised controlled trial

M. V. Karg, A. Bosch, D. Kannenkeril, K. Striepe, C. Ott, M. P. Schneider, F. Boemke-Zelch, P. Linz, A. M. Nagel, J. Titze, M. Uder, R. E. Schmieder

Open Access Original investigation

The effect of dapagliflozin treatment on epicardial adipose tissue volume

Takao Sato, Yoshifusa Aizawa, Sho Yuasa, Shohei Kishi, Koichi Fuse, Satoshi Fujita, Yoshio Ikeda, Hitoshi Kitazawa, Minoru Takahashi, Masahito Sato, Masaaki Okabe

Open Access Original investigation

Increased myocardial extracellular volume assessed by cardiovascular magnetic resonance T1 mapping and its determinants in type 2 diabetes mellitus patients with normal myocardial systolic strain

Yukun Cao, Wenjuan Zeng, Yue Cui, Xiangchuang Kong, Miao Wang, Jie Yu, Shan Zhang, Jing Song, Xu Yan, Andreas Greiser, Heshui Shi

Open Access Original investigation

Effects of 6-month treatment with the glucagon like peptide-1 analogue liraglutide on arterial stiffness, left ventricular myocardial deformation and oxidative stress in subjects with newly diagnosed type 2 diabetes

Vaia Lambadiari, George Pavlidis, Foteini Kousathana, Maria Varoudi, Dimitrios Vlastos, Eirini Maratou, Dimitrios Georgiou, Ioanna Andreadou, John Parissis, Helen Triantafyllidi, John Lekakis, Efstathios Iliodromitis, George Dimitriadis, Ignatios Ikonomidis

Open Access Original investigation

Increased epicardial adipose tissue thickness is a predictor of new-onset diabetes mellitus in patients with coronary artery disease treated with high-intensity statins

Jeehoon Kang, Young-Chan Kim, Jin Joo Park, Sehun Kim, Si-Hyuck Kang, Young Jin Cho, Yeonyee E. Yoon, Il-Young Oh, Chang-Hwan Yoon, Jung-Won Suh, Young-Seok Cho, Tae-Jin Youn, In-Ho Chae, Dong-Ju Choi

Open Access Original investigation

Relationship between cardiac microvascular dysfunction measured with 82Rubidium-PET and albuminuria in patients with diabetes mellitus

Louis Potier, Renata Chequer, Ronan Roussel, Kamel Mohammedi, Souad Sismail, Agnès Hartemann, Chloé Amouyal, Michel Marre, Dominique Le Guludec, Fabien Hyafil

Open Access Original investigation

Sitagliptin improved glucose assimilation in detriment of fatty-acid utilization in experimental type-II diabetes: role of GLP-1 isoforms in Glut4 receptor trafficking

E. Ramírez, B. Picatoste, A. González-Bris, M. Oteo, F. Cruz, A. Caro-Vadillo, J. Egido, J. Tuñón, M. A. Morcillo, Ó. Lorenzo

Open Access Original investigation

Comparison of speckle-tracking echocardiography with invasive hemodynamics for the detection of characteristic cardiac dysfunction in type-1 and type-2 diabetic rat models

Csaba Mátyás, Attila Kovács, Balázs Tamás Németh, Attila Oláh, Szilveszter Braun, Márton Tokodi, Bálint András Barta, Kálmán Benke, Mihály Ruppert, Bálint Károly Lakatos, Béla Merkely, Tamás Radovits

Open Access Original investigation

Mendelian randomization analysis to assess a causal effect of haptoglobin on macroangiopathy in Chinese type 2 diabetes patients

Shiyun Wang, Jie Wang, Rong Zhang, Tao Wang, Dandan Yan, Zhen He, Feng Jiang, Cheng Hu, Weiping Jia

Open Access Original investigation

Influence of apocynin on cardiac remodeling in rats with streptozotocin-induced diabetes mellitus

R. Gimenes, C. Gimenes, C. M. Rosa, N. P. Xavier, D. H. S. Campos, A. A. H. Fernandes, M. D. M. Cezar, G. N. Guirado, L. U. Pagan, I. D. Chaer, D. C. Fernandes, F. R. Laurindo, A. C. Cicogna, M. P. Okoshi, K. Okoshi

Open Access Original investigation

p66Shc gene expression in peripheral blood mononuclear cells and progression of diabetic complications

Gian Paolo Fadini, Mattia Albiero, Benedetta Maria Bonora, Nicol Poncina, Saula Vigili de Kreutzenberg, Angelo Avogaro

Open Access Original investigation

Metabolic syndrome severity is significantly associated with future coronary heart disease in Type 2 diabetes

Matthew J. Gurka, Yi Guo, Stephanie L. Filipp, Mark D. DeBoer

Open Access Original investigation

Individualised treatment targets in patients with type-2 diabetes and hypertension

Roland E. Schmieder, Diethelm Tschöpe, Cornelia Koch, Taoufik Ouarrak, Anselm K. Gitt, Sibel Avsar, Peter Bramlage, Eva Duetting, Anselm K. Gitt, Cornelia Koch, Alfons Müller, Alexander Neumer, Taoufik Ouarrak, Roland E. Schmieder, Steffen Schneider, Diethelm Tschöpe

Open Access Original investigation

Association of depression with evolution of heart failure in patients with type 2 diabetes mellitus

Ying Wang, Hong Yang, Mark Nolan, John Burgess, Kazuaki Negishi, Thomas H. Marwick

Open Access Original investigation

Glitazones and alpha-glucosidase inhibitors as the second-line oral anti-diabetic agents added to metformin reduce cardiovascular risk in Type 2 diabetes patients: a nationwide cohort observational study

Cheng-Wei Chan, Chu-Leng Yu, Jiunn-Cherng Lin, Yu-Cheng Hsieh, Che-Chen Lin, Chen-Ying Hung, Cheng-Hung Li, Ying-Chieh Liao, Chu-Pin Lo, Jin-Long Huang, Ching-Heng Lin, Tsu-Juey Wu

Open Access Original investigation

Increase in relative skeletal muscle mass over time and its inverse association with metabolic syndrome development: a 7-year retrospective cohort study

Gyuri Kim, Seung-Eun Lee, Ji Eun Jun, You-Bin Lee, Jiyeon Ahn, Ji Cheol Bae, Sang-Man Jin, Kyu Yeon Hur, Jae Hwan Jee, Moon-Kyu Lee, Jae Hyeon Kim

Open Access Original investigation

Effect of sitagliptin on tissue characteristics of the carotid wall in patients with type 2 diabetes: a post hoc sub-analysis of the sitagliptin preventive study of intima-media thickness evaluation (SPIKE)

Naoto Katakami, Tomoya Mita, Yoko Irie, Mitsuyoshi Takahara, Taka-aki Matsuoka, Masahiko Gosho, Hirotaka Watada, Iichiro Shimomura

Open Access Original investigation

Impact of diabetes and early revascularization on the need for late and repeat procedures

Ady Orbach, David A. Halon, Ronen Jaffe, Ronen Rubinshtein, Basheer Karkabi, Moshe Y. Flugelman, Barak Zafrir

Open Access Review

Reduced coronary collateralization in type 2 diabetic patients with chronic total occlusion

Ying Shen, Feng Hua Ding, Yang Dai, Xiao Qun Wang, Rui Yan Zhang, Lin Lu, Wei Feng Shen

Open Access Original investigation

Control of glycemia and blood pressure in British adults with diabetes mellitus and subsequent therapy choices: a comparison across health states

Finlay A. McAlister, Brendan Cord Lethebe, Caitlin Lambe, Tyler Williamson, Mark Lowerison

Open Access Original investigation

Reactive hyperemia index (RHI) and cognitive performance indexes are associated with histologic markers of liver disease in subjects with non-alcoholic fatty liver disease (NAFLD): a case control study

Antonino Tuttolomondo, Salvatore Petta, Alessandra Casuccio, Carlo Maida, Vittoriano Della Corte, Mario Daidone, Domenico Di Raimondo, Rosaria Pecoraro, Roberto Fonte, Anna Cirrincione, Rita Zafonte, Daniela Cabibi, Calogero Cammà, Vito Di Marco, Anna Licata, Franco Magliozzo, Giulio Marchesini, Giovanni Merlino, Antonio Craxì, Antonio Pinto

Open Access Original investigation

Relationship between polyunsaturated fatty acid composition in serum phospholipids, systemic low-grade inflammation, and glycemic control in patients with type 2 diabetes and atherosclerotic cardiovascular disease

Malgorzata Poreba, Pawel Rostoff, Aleksander Siniarski, Magdalena Mostowik, Renata Golebiowska-Wiatrak, Jadwiga Nessler, Anetta Undas, Grzegorz Gajos

Open Access Commentary

Report from the 3rd Cardiovascular Outcome Trial (CVOT) Summit of the Diabetes & Cardiovascular Disease (D&CVD) EASD Study Group

Oliver Schnell, Eberhard Standl, Doina Catrinoiu, Stefano Genovese, Nebojsa Lalic, Katarina Lalic, Jan Skrha, Paul Valensi, Antonio Ceriello

Open Access Original investigation

Potential role of insulin receptor isoforms and IGF receptors in plaque instability of human and experimental atherosclerosis

Nuria Beneit, José Luis Martín-Ventura, Carlota Rubio-Longás, Óscar Escribano, Gema García-Gómez, Silvia Fernández, Giorgio Sesti, Marta Letizia Hribal, Jesús Egido, Almudena Gómez-Hernández, Manuel Benito

Open Access Original investigation

MicroRNA-19a contributes to the epigenetic regulation of tissue factor in diabetes

Marco Witkowski, Termeh Tabaraie, Daniel Steffens, Julian Friebel, Andrea Dörner, Carsten Skurk, Mario Witkowski, Bernd Stratmann, Diethelm Tschoepe, Ulf Landmesser, Ursula Rauch

Open Access Original investigation

Cardiovascular magnetic resonance measures of aortic stiffness in asymptomatic patients with type 2 diabetes: association with glycaemic control and clinical outcomes

Peter P. Swoboda, Bara Erhayiem, Rachel Kan, Adam K. McDiarmid, Pankaj Garg, Tarique A. Musa, Laura E. Dobson, Klaus K. Witte, Mark T. Kearney, Julian H. Barth, Ramzi Ajjan, John P. Greenwood, Sven Plein

Open Access Original investigation

Glycemic variability in continuous glucose monitoring is inversely associated with baroreflex sensitivity in type 2 diabetes: a preliminary report

Daisuke Matsutani, Masaya Sakamoto, Hiroyuki Iuchi, Souichirou Minato, Hirofumi Suzuki, Yosuke Kayama, Norihiko Takeda, Ryuzo Horiuchi, Kazunori Utsunomiya

Open Access Original investigation

Cardiovascular disease in a nationwide population of Danish women with polycystic ovary syndrome

Dorte Glintborg, Katrine Hass Rubin, Mads Nybo, Bo Abrahamsen, Marianne Andersen

Open Access Original investigation

Rationale, design, and baseline characteristics of the CArdiovascular safety and Renal Microvascular outcomE study with LINAgliptin (CARMELINA®): a randomized, double-blind, placebo-controlled clinical trial in patients with type 2 diabetes and high cardio-renal risk

Julio Rosenstock, Vlado Perkovic, John H. Alexander, Mark E. Cooper, Nikolaus Marx, Michael J. Pencina, Robert D. Toto, Christoph Wanner, Bernard Zinman, David Baanstra, Egon Pfarr, Michaela Mattheus, Uli C. Broedl, Hans-Juergen Woerle, Jyothis T. George, Maximilian von Eynatten, Darren K. McGuire

Open Access Original investigation

Relationships between epicardial adipose tissue thickness and adipo-fibrokine indicator profiles post-myocardial infarction

Olga Gruzdeva, Evgenya Uchasova, Yulia Dyleva, Daria Borodkina, Olga Akbasheva, Ekaterina Belik, Viktoria Karetnikova, Natalia Brel, Alexander Kokov, Vasiliy Kashtalap, Olga Barbarash

Open Access Original investigation

Association between triglyceride glucose index and arterial stiffness in Korean adults

Sang Bae Lee, Chul Woo Ahn, Byoung Kwon Lee, Shinae Kang, Ji Sun Nam, Ji Hong You, Min Jin Kim, Min Kyung Kim, Jong Suk Park

Open Access Correction

Correction to: HbA1c versus oral glucose tolerance test as a method to diagnose diabetes mellitus in vascular surgery patients

Iren D. Hjellestad, Marianne C. Astor, Roy M. Nilsen, Eirik Søfteland, Torbjørn Jonung

Open Access Original investigation

Exercise capacity in diabetes mellitus is predicted by activity status and cardiac size rather than cardiac function: a case control study

Timothy J. Roberts, Andrew T. Burns, Richard J. MacIsaac, Andrew I. MacIsaac, David L. Prior, André La Gerche

Open Access Original investigation

Bone markers and cardiovascular risk in type 2 diabetes patients

Sabine R. Zwakenberg, Yvonne T. van der Schouw, Casper G. Schalkwijk, Annemieke M. W. Spijkerman, Joline W. J. Beulens

Open Access Original investigation

The role of obesity in carotid plaque instability: interaction with age, gender, and cardiovascular risk factors

Valentina Rovella, Lucia Anemona, Marina Cardellini, Manuel Scimeca, Andrea Saggini, Giuseppe Santeusanio, Elena Bonanno, Manuela Montanaro, Iacopo Maria Legramante, Arnaldo Ippoliti, Nicola Di Daniele, Massimo Federici, Alessandro Mauriello

Open Access Original investigation

HbA1c variability and diabetic peripheral neuropathy in type 2 diabetic patients

Jian-bin Su, Li-hua Zhao, Xiu-lin Zhang, Hong-li Cai, Hai-yan Huang, Feng Xu, Tong Chen, Xue-qin Wang

Open Access Original investigation

Liraglutide downregulates hepatic LDL receptor and PCSK9 expression in HepG2 cells and db/db mice through a HNF-1a dependent mechanism

Sheng-Hua Yang, Rui-Xia Xu, Chuan-Jue Cui, Yin Wang, Ying Du, Zhi-Guo Chen, Yu-Hong Yao, Chun-Yan Ma, Cheng-Gang Zhu, Yuan-Lin Guo, Na-Qiong Wu, Jing Sun, Bu-Xing Chen, Jian-Jun Li

Open Access Correction

Correction to: Type 2 diabetes-associated carotid plaque burden is increased in patients with retinopathy compared to those without retinopathy

Núria Alonso, Alicia Traveset, Esther Rubinat, Emilio Ortega, Nuria Alcubierre, Jordi Sanahuja, Marta Hernández, Angels Betriu, Carmen Jurjo, Elvira Fernández, Didac Mauricio

Open Access Original investigation

Urinary proteomics for prediction of mortality in patients with type 2 diabetes and microalbuminuria

Gemma E. Currie, Bernt Johan von Scholten, Sheon Mary, Jose-Luis Flores Guerrero, Morten Lindhardt, Henrik Reinhard, Peter K. Jacobsen, William Mullen, Hans-Henrik Parving, Harald Mischak, Peter Rossing, Christian Delles

Open Access Original investigation

The effect of change in fasting glucose on the risk of myocardial infarction, stroke, and all-cause mortality: a nationwide cohort study

Gyeongsil Lee, Sung Min Kim, Seulggie Choi, Kyuwoong Kim, Su-Min Jeong, Joung Sik Son, Jae-Moon Yun, Sang Min Park

Open Access Original investigation

Empagliflozin influences blood viscosity and wall shear stress in subjects with type 2 diabetes mellitus compared with incretin-based therapy

Concetta Irace, Francesco Casciaro, Faustina Barbara Scavelli, Rosa Oliverio, Antonio Cutruzzolà, Claudio Cortese, Agostino Gnasso

Open Access Original investigation

Liraglutide suppresses non-esterified free fatty acids and soluble vascular cell adhesion molecule-1 compared with metformin in patients with recent-onset type 2 diabetes

Xiao-min Chen, Wen-qiang Zhang, Yuan Tian, Li-fen Wang, Chan-chan Chen, Chuan-mei Qiu

Open Access Original investigation

Antidiabetic treatment patterns and specialty care utilization among patients with type 2 diabetes and cardiovascular disease

Kevin M. Pantalone, Anita D. Misra-Hebert, Todd M. Hobbs, Xinge Ji, Sheldon X. Kong, Alex Milinovich, Wayne Weng, Janine Bauman, Rahul Ganguly, Bartolome Burguera, Michael W. Kattan, Robert S. Zimmerman

Open Access Original investigation

Sarcopenic obesity assessed using dual energy X-ray absorptiometry (DXA) can predict cardiovascular disease in patients with type 2 diabetes: a retrospective observational study

Tatsuya Fukuda, Ryotaro Bouchi, Takato Takeuchi, Kazutaka Tsujimoto, Isao Minami, Takanobu Yoshimoto, Yoshihiro Ogawa

Open Access Original investigation

Cardiovascular disease risk factor responses to a type 2 diabetes care model including nutritional ketosis induced by sustained carbohydrate restriction at 1 year: an open label, non-randomized, controlled study

Nasir H. Bhanpuri, Sarah J. Hallberg, Paul T. Williams, Amy L. McKenzie, Kevin D. Ballard, Wayne W. Campbell, James P. McCarter, Stephen D. Phinney, Jeff S. Volek

Open Access Review

Diabetes, cardiovascular disease and the microcirculation

W. David Strain, P. M. Paldánius

Open Access Original investigation

Prevalence of left ventricular systolic dysfunction and heart failure with reduced ejection fraction in men and women with type 2 diabetes mellitus: a systematic review and meta-analysis

Selma Bouthoorn, Aisha Gohar, Gideon Valstar, Hester M. den Ruijter, J. B. Reitsma, Arno W. Hoes, Frans H. Rutten, Hester M. den Ruijter, Frans H. Rutten, Arno W. Hoes, Gerard Pasterkamp, Marc Spaanderman, Chahinda Ghossein-Doha, Folkert Asselbergs, Erik Biessen, Michiel Bots, Caroline Cheng, Marijke Faas, Imo Hoefer, Johan Kuiper, Yigal Pinto, Torsten Plösch, Sicco Scherjon, Marianne Verhaar, Anton Jan van Zonneveld, Yolande Appelman, Rick Grobbee, Carolyn Lam, Tim Leiner

Open Access Review

The role of dipeptidylpeptidase-4 inhibitors in management of cardiovascular disease in diabetes; focus on linagliptin

Annayya R. Aroor, Camila Manrique-Acevedo, Vincent G. DeMarco

Open Access Original investigation

The effect of DPP-4 inhibition to improve functional outcome after stroke is mediated by the SDF-1α/CXCR4 pathway

Fausto Chiazza, Harald Tammen, Hiranya Pintana, Grazyna Lietzau, Massimo Collino, Thomas Nyström, Thomas Klein, Vladimer Darsalia, Cesare Patrone

Open Access Original investigation

Novel risk genes identified in a genome-wide association study for coronary artery disease in patients with type 1 diabetes

Romain Charmet, Seamus Duffy, Sareh Keshavarzi, Beata Gyorgy, Michel Marre, Peter Rossing, Amy Jayne McKnight, Alexander P. Maxwell, Tarun veer Singh Ahluwalia, Andrew D. Paterson, David-Alexandre Trégouët, Samy Hadjadj

Open Access Original investigation

SGLT2 inhibition via dapagliflozin improves generalized vascular dysfunction and alters the gut microbiota in type 2 diabetic mice

Dustin M. Lee, Micah L. Battson, Dillon K. Jarrell, Shuofei Hou, Kayl E. Ecton, Tiffany L. Weir, Christopher L. Gentile

Open Access Original investigation

Prognostic value of the Stanniocalcin-2/PAPP-A/IGFBP-4 axis in ST-segment elevation myocardial infarction

Germán Cediel, Ferran Rueda, Claus Oxvig, Teresa Oliveras, Carlos Labata, Oriol de Diego, Marc Ferrer, M. Cruz Aranda-Nevado, Judith Serra-Gregori, Julio Núñez, Cosme García, Antoni Bayes-Genis

Open Access Original investigation

Exercise training and endothelial function in patients with type 2 diabetes: a meta-analysis

Shanhu Qiu, Xue Cai, Han Yin, Zilin Sun, Martina Zügel, Jürgen Michael Steinacker, Uwe Schumann

Open Access Original investigation

The synergistic effects of saxagliptin and metformin on CD34+ endothelial progenitor cells in early type 2 diabetes patients: a randomized clinical trial

Fiona J. Dore, Cleyton C. Domingues, Neeki Ahmadi, Nabanita Kundu, Yana Kropotova, Sara Houston, Carol Rouphael, Aytan Mammadova, Linda Witkin, Anamil Khiyami, Richard L. Amdur, Sabyasachi Sen

Open Access Original investigation

Diabetic retinopathy is associated with the presence and burden of subclinical carotid atherosclerosis in type 1 diabetes

Marc Carbonell, Esmeralda Castelblanco, Xavier Valldeperas, Àngels Betriu, Alícia Traveset, Minerva Granado-Casas, Marta Hernández, Federico Vázquez, Mariona Martín, Esther Rubinat, Albert Lecube, Josep Franch-Nadal, Elvira Fernández, Manel Puig-Domingo, Angelo Avogaro, Núria Alonso, Dídac Mauricio

Open Access Original investigation

Associations of coronary artery calcified plaque density with mortality in type 2 diabetes: the Diabetes Heart Study

Laura M. Raffield, Amanda J. Cox, Michael H. Criqui, Fang-Chi Hsu, James G. Terry, Jianzhao Xu, Barry I. Freedman, J. Jeffrey Carr, Donald W. Bowden

Open Access Original investigation

Adverse effects of Hif1a mutation and maternal diabetes on the offspring heart

Radka Cerychova, Romana Bohuslavova, Frantisek Papousek, David Sedmera, Pavel Abaffy, Vladimir Benes, Frantisek Kolar, Gabriela Pavlinkova

Open Access Original investigation

Childhood retinol-binding protein 4 (RBP4) levels predicting the 10-year risk of insulin resistance and metabolic syndrome: the BCAMS study

Ge Li, Issy C. Esangbedo, Lu Xu, Junling Fu, Lujiao Li, Dan Feng, Lanwen Han, Xinhua Xiao, Mingyao Li, Jie Mi, Ming Li, Shan Gao, Steven M. Willi

Open Access Original investigation

Prevalence and incidence of complications at diagnosis of T2DM and during follow-up by BMI and ethnicity: a matched case–control analysis

Ebenezer S. Owusu Adjah, Srikanth Bellary, Wasim Hanif, Kiran Patel, Kamlesh Khunti, Sanjoy K. Paul

Open Access Original investigation

Effects of linagliptin on endothelial function and postprandial lipids in coronary artery disease patients with early diabetes: a randomized, placebo-controlled, double-blind trial

Norbert J. Tripolt, Felix Aberer, Regina Riedl, Jasmin Url, Gudrun Dimsity, Andreas Meinitzer, Tatjana Stojakovic, Faisal Aziz, Ronald Hödl, Gabriele Brachtl, Dirk Strunk, Marianne Brodmann, Franz Hafner, Harald Sourij

Open Access Original investigation

No detectable differential microRNA expression between non-atherosclerotic arteries of type 2 diabetic patients (treated or untreated with metformin) and non-diabetic patients

Lasse Bach Steffensen, Søren Feddersen, Simone Rørdam Preil, Lars Melholt Rasmussen

Open Access Original investigation

Effect of canagliflozin on left ventricular diastolic function in patients with type 2 diabetes

Daisuke Matsutani, Masaya Sakamoto, Yosuke Kayama, Norihiko Takeda, Ryuzo Horiuchi, Kazunori Utsunomiya

Open Access Original investigation

Donor artery stenosis interactions with diastolic blood pressure on coronary collateral flow in type 2 diabetic patients with chronic total occlusion

Ying Shen, Zhen Kun Yang, Jian Hu, Xiao Qun Wang, Yang Dai, Su Zhang, Rui Yan Zhang, Lin Lu, Feng Hua Ding, Wei Feng Shen

Open Access Original investigation

Burden of cardiovascular risk factors and disease among patients with type 1 diabetes: results of the Australian National Diabetes Audit (ANDA)

Anthony Pease, Arul Earnest, Sanjeeva Ranasinha, Natalie Nanayakkara, Danny Liew, Natalie Wischer, Sofianos Andrikopoulos, Sophia Zoungas

Open Access Original investigation

Influence of high density lipoprotein cholesterol levels on circulating monocytic angiogenic cells functions in individuals with type 2 diabetes mellitus

Daniela Lucchesi, Simona Georgiana Popa, Veronica Sancho, Laura Giusti, Monia Garofolo, Giuseppe Daniele, Laura Pucci, Roberto Miccoli, Giuseppe Penno, Stefano Del Prato

Open Access Original investigation

Sex-specific associations between adolescent categories of BMI with cardiovascular and non-cardiovascular mortality in midlife

Ariel Furer, Arnon Afek, Omri Orr, Liron Gershovitz, Moran Landau Rabbi, Estela Derazne, Orit Pinhas-Hamiel, Noam Fink, Adi Leiba, Amir Tirosh, Jeremy D. Kark, Gilad Twig

Open Access Original investigation

Influence of micro- and macro-vascular disease and Tumor Necrosis Factor Receptor 1 on the level of lower-extremity amputation in patients with type 2 diabetes

Fabrice Schneider, Pierre-Jean Saulnier, Elise Gand, Mathieu Desvergnes, Nicolas Lefort, Eric Thorin, Nathalie Thorin-Trescases, Kamel Mohammedi, Stéphanie Ragot, Jean-Baptiste Ricco, Samy Hadjadj

Open Access Original investigation

Skin autofluorescence predicts major adverse cardiovascular events in patients with type 1 diabetes: a 7-year follow-up study

C. Blanc-Bisson, F. L. Velayoudom-Cephise, A. Cougnard-Gregoire, C. Helmer, K. Rajaobelina, C. Delcourt, L. Alexandre, L. Blanco, K. Mohammedi, M. Monlun, V. Rigalleau

Open Access Original investigation

Triglyceride-mediated influence of serum angiopoietin-like protein 8 on subclinical atherosclerosis in type 2 diabetic patients: results from the GDMD study in China

Tianpeng Zheng, Bo Ge, Hongbo Liu, Bo Chen, Linyuan Qin, Liuping Xiao, Jianfei Song

Open Access Original investigation

Comparing the inflammatory profiles for incidence of diabetes mellitus and cardiovascular diseases: a prospective study exploring the ‘common soil’ hypothesis

Xue Bao, Yan Borné, Linda Johnson, Iram Faqir Muhammad, Margaretha Persson, Kaijun Niu, Gunnar Engström

Open Access Original investigation

Association between abdominal adiposity and subclinical measures of left-ventricular remodeling in diabetics, prediabetics and normal controls without history of cardiovascular disease as measured by magnetic resonance imaging: results from the KORA-FF4 Study

Christopher L. Schlett, Roberto Lorbeer, Carolyn Arndt, Sigrid Auweter, Jürgen Machann, Holger Hetterich, Birgit Linkohr, Wolfgang Rathmann, Annette Peters, Fabian Bamberg

Open Access Original investigation

Inhibition of calcium/calmodulin-dependent kinase II restores contraction and relaxation in isolated cardiac muscle from type 2 diabetic rats

Lorna J. Daniels, Rachel S. Wallace, Olivia M. Nicholson, Genevieve A. Wilson, Fiona J. McDonald, Peter P. Jones, J. Chris Baldi, Regis R. Lamberts, Jeffrey R. Erickson

Open Access Original investigation

Non-culprit plaque characteristics in acute coronary syndrome patients with raised hemoglobinA1c: an intravascular optical coherence tomography study

Shaotao Zhang, Jiannan Dai, Haibo Jia, Sining Hu, Hongwei Du, Ning Li, Yongpeng Zou, Yanan Zou, Shenhong Jing, Yan Wang, Rong Sun, Bo Yu

Open Access Original investigation

Abdominal subcutaneous adipose tissue: a favorable adipose depot for diabetes?

Peizhu Chen, Xuhong Hou, Gang Hu, Li Wei, Lei Jiao, Hongmei Wang, Siyu Chen, Jingzhu Wu, Yuqian Bao, Weiping Jia

Open Access Review

Actions of metformin and statins on lipid and glucose metabolism and possible benefit of combination therapy

Mariël F. van Stee, Albert A. de Graaf, Albert K. Groen

Open Access Original investigation

Association between epicardial adipose tissue, high-sensitivity C-reactive protein and myocardial dysfunction in middle-aged men with suspected metabolic syndrome

Dong-Hyuk Cho, Hyung Joon Joo, Mi-Na Kim, Do-Sun Lim, Wan Joo Shim, Seong-Mi Park

Open Access Original investigation

Prognostic impact of HbA1c variability on long-term outcomes in patients with heart failure and type 2 diabetes mellitus

Jun Gu, Jian-an Pan, Yu-qi Fan, Hui-li Zhang, Jun-feng Zhang, Chang-qian Wang

Open Access Review

Omega-3 polyunsaturated fatty acids favourably modulate cardiometabolic biomarkers in type 2 diabetes: a meta-analysis and meta-regression of randomized controlled trials

Lauren L. O’Mahoney, Jamie Matu, Oliver J. Price, Karen M. Birch, Ramzi A. Ajjan, Diane Farrar, Robyn Tapp, Daniel J. West, Kevin Deighton, Matthew D. Campbell

Open Access Original investigation

Dual inhibition of sodium–glucose linked cotransporters 1 and 2 exacerbates cardiac dysfunction following experimental myocardial infarction

Kim A. Connelly, Yanling Zhang, Jean-François Desjardins, Kerri Thai, Richard E. Gilbert

Open Access Original investigation

Visit-to-visit HbA1c variability is inversely related to baroreflex sensitivity independently of HbA1c value in type 2 diabetes

Daisuke Matsutani, Masaya Sakamoto, Soichiro Minato, Yosuke Kayama, Norihiko Takeda, Ryuzo Horiuchi, Kazunori Utsunomiya

Open Access Review

Potential mechanisms responsible for cardioprotective effects of sodium–glucose co-transporter 2 inhibitors

Charshawn Lahnwong, Siriporn C. Chattipakorn, Nipon Chattipakorn

Open Access Original investigation

β Cell-specific deletion of guanylyl cyclase A, the receptor for atrial natriuretic peptide, accelerates obesity-induced glucose intolerance in mice

Sabine Tauscher, Hitoshi Nakagawa, Katharina Völker, Franziska Werner, Lisa Krebes, Tamara Potapenko, Sören Doose, Andreas L. Birkenfeld, Hideo A. Baba, Michaela Kuhn

Open Access Original investigation

Beneficial effects of cherry consumption as a dietary intervention for metabolic, hepatic and vascular complications in type 2 diabetic rats

Remmelt Van der Werf, Catherine Walter, William Bietiger, Elodie Seyfritz, Carole Mura, Claude Peronet, Julie Legrandois, Dalal Werner, Said Ennahar, Fabien Digel, Elisa Maillard-Pedracini, Michel Pinget, Nathalie Jeandidier, Eric Marchioni, Séverine Sigrist, Stéphanie Dal

Open Access Original investigation

Glucose-sensing microRNA-21 disrupts ROS homeostasis and impairs antioxidant responses in cellular glucose variability

Lucia La Sala, Simona Mrakic-Sposta, Stefano Micheloni, Francesco Prattichizzo, Antonio Ceriello

Open Access Original investigation

Canagliflozin attenuates the progression of atherosclerosis and inflammation process in APOE knockout mice

Νarjes Nasiri-Ansari, Georgios K. Dimitriadis, Georgios Agrogiannis, Despoina Perrea, Ioannis D. Kostakis, Gregory Kaltsas, Athanasios G. Papavassiliou, Harpal S. Randeva, Eva Kassi

Open Access Original investigation

Dissimilar impact of type 2 diabetes on cardiovascular outcomes according to age categories: a nationwide population study from Hungary

Zoltán Kiss, György Rokszin, Zsolt Abonyi-Tóth, György Jermendy, Péter Kempler, Dániel Aradi, István Wittmann

Open Access Original investigation

Glycemic control by the SGLT2 inhibitor empagliflozin decreases aortic stiffness, renal resistivity index and kidney injury

Annayya R. Aroor, Nitin A. Das, Andrea J. Carpenter, Javad Habibi, Guanghong Jia, Francisco I. Ramirez-Perez, Luis Martinez-Lemus, Camila M. Manrique-Acevedo, Melvin R. Hayden, Cornel Duta, Ravi Nistala, Eric Mayoux, Jaume Padilla, Bysani Chandrasekar, Vincent G. DeMarco

Open Access Original investigation

Progression of cardiovascular autonomic neuropathy and cardiovascular disease in type 2 diabetes

Jae-Seung Yun, Yong-Moon Park, Seon-Ah Cha, Yu-Bae Ahn, Seung-Hyun Ko

Open Access Original investigation

Plasma copeptin, kidney disease, and risk for cardiovascular morbidity and mortality in two cohorts of type 2 diabetes

Gilberto Velho, Stéphanie Ragot, Ray El Boustany, Pierre-Jean Saulnier, Mathilde Fraty, Kamel Mohammedi, Frédéric Fumeron, Louis Potier, Michel Marre, Samy Hadjadj, Ronan Roussel

Open Access Original investigation

Regulation of diabetic cardiomyopathy by caloric restriction is mediated by intracellular signaling pathways involving ‘SIRT1 and PGC-1α’

Maayan Waldman, Keren Cohen, Dor Yadin, Vadim Nudelman, Dan Gorfil, Michal Laniado-Schwartzman, Ran Kornwoski, Dan Aravot, Nader G. Abraham, Michael Arad, Edith Hochhauser

Open Access Original investigation

Low muscle quality in Japanese type 2 diabetic patients with visceral fat accumulation

Jun Murai, Hitoshi Nishizawa, Akihito Otsuka, Shiro Fukuda, Yoshimitsu Tanaka, Hirofumi Nagao, Yasuna Sakai, Masahide Suzuki, Shinji Yokota, Hidetoshi Tada, Mayumi Doi, Yuya Fujishima, Shunbun Kita, Tohru Funahashi, Norikazu Maeda, Tadashi Nakamura, Iichiro Shimomura

Open Access Original investigation

Overweight and obesity impair left ventricular systolic function as measured by left ventricular ejection fraction and global longitudinal strain

Peter Blomstrand, Peter Sjöblom, Mats Nilsson, Magnus Wijkman, Martin Engvall, Toste Länne, Fredrik H. Nyström, Carl Johan Östgren, Jan Engvall

Open Access Original investigation

Biodegradable polymer drug-eluting stents versus second-generation drug-eluting stents in patients with and without diabetes mellitus: a single-center study

Xiao-Fang Tang, Yuan-Liang Ma, Ying Song, Jing-Jing Xu, Yi Yao, Chen He, Huan-Huan Wang, Ping Jiang, Lin Jiang, Ru Liu, Zhan Gao, Xue-yan Zhao, Shu-Bin Qiao, Yue-Jin Yang, Run-Lin Gao, Bo Xu, Jin-Qing Yuan

Open Access Correction

Correction to: Regulation of diabetic cardiomyopathy by caloric restriction is mediated by intracellular signaling pathways involving ‘SIRT1 and PGC-1α’

Maayan Waldman, Keren Cohen, Dor Yadin, Vadim Nudelman, Dan Gorfil, Michal Laniado-Schwartzman, Ran Kornwoski, Dan Aravot, Nader G. Abraham, Michael Arad, Edith Hochhauser

Open Access Original investigation

Glycemic variability determined with a continuous glucose monitoring system can predict prognosis after acute coronary syndrome

Hironori Takahashi, Noriaki Iwahashi, Jin Kirigaya, Shunsuke Kataoka, Yugo Minamimoto, Masaomi Gohbara, Takeru Abe, Kozo Okada, Yasushi Matsuzawa, Masaaki Konishi, Nobuhiko Maejima, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Kouichi Tamura, Kazuo Kimura

Open Access Original investigation

Development of predictive risk models for major adverse cardiovascular events among patients with type 2 diabetes mellitus using health insurance claims data

James B. Young, Marjolaine Gauthier-Loiselle, Robert A. Bailey, Ameur M. Manceur, Patrick Lefebvre, Morris Greenberg, Marie-Hélène Lafeuille, Mei Sheng Duh, Brahim Bookhart, Carol H. Wysham

Open Access Original investigation

Metabolomic profiling implicates adiponectin as mediator of a favorable lipoprotein profile associated with NT-proBNP

Annette Masuch, Maik Pietzner, Martin Bahls, Kathrin Budde, Gabi Kastenmüller, Stephanie Zylla, Anna Artati, Jerzy Adamski, Henry Völzke, Marcus Dörr, Stephan B. Felix, Matthias Nauck, Nele Friedrich

Open Access Review

Association between insulin resistance and the development of cardiovascular disease

Valeska Ormazabal, Soumyalekshmi Nair, Omar Elfeky, Claudio Aguayo, Carlos Salomon, Felipe A. Zuñiga

Open Access Original investigation

MiR-21 protected against diabetic cardiomyopathy induced diastolic dysfunction by targeting gelsolin

Beibei Dai, Huaping Li, Jiahui Fan, Yanru Zhao, Zhongwei Yin, Xiang Nie, Dao Wen Wang, Chen Chen

Open Access Original investigation

Midlife development of type 2 diabetes and hypertension in women by history of hypertensive disorders of pregnancy

Simon Timpka, Amanda Markovitz, Tommy Schyman, Ingrid Mogren, Abigail Fraser, Paul W. Franks, Janet W. Rich-Edwards

Open Access Original investigation

Type 2 diabetes is independently associated with all-cause mortality secondary to ventricular tachyarrhythmias

Kathrin Weidner, Michael Behnes, Tobias Schupp, Jonas Rusnak, Linda Reiser, Armin Bollow, Gabriel Taton, Thomas Reichelt, Dominik Ellguth, Niko Engelke, Jorge Hoppner, Ibrahim El-Battrawy, Kambis Mashayekhi, Christel Weiß, Martin Borggrefe, Ibrahim Akin

Open Access Original investigation

The role of physical activity in the development of first cardiovascular disease event: a tree-structured survival analysis of the Danish ADDITION-PRO cohort

Hanan Amadid, Nanna B. Johansen, Anne-Louise Bjerregaard, Søren Brage, Kristine Færch, Torsten Lauritzen, Daniel R. Witte, Annelli Sandbæk, Marit E. Jørgensen, Dorte Vistisen

Open Access Original investigation

ACE2 polymorphisms associated with cardiovascular risk in Uygurs with type 2 diabetes mellitus

Cheng Liu, Yanfang Li, Tianwang Guan, Yanxian Lai, Yan Shen, Abudurexiti Zeyaweiding, Haiyan Zhao, Fang Li, Tutiguli Maimaiti

Open Access Original investigation

Early vascular parameters in the micro- and macrocirculation in type 2 diabetes

Dennis Kannenkeril, Agnes Bosch, Joanna Harazny, Marina Karg, Susanne Jung, Christian Ott, Roland E. Schmieder

Open Access Original investigation

Both pre-frailty and frailty increase healthcare utilization and adverse health outcomes in patients with type 2 diabetes mellitus

Chia-Ter Chao, Jui Wang, Kuo-Liong Chien, Hung-Bin Tsai, Chih-Kang Chiang, Jenq-Wen Huang, Ding-Cheng Chan, Kuan-Yu Hung

Open Access Original investigation

Impaired glucose metabolism is associated with increased thrombin generation potential in patients undergoing angioplasty and stenting

Silvia Lee, Cihan Ay, Christoph W. Kopp, Simon Panzer, Thomas Gremmel

Open Access Original investigation

Impact of dapagliflozin on left ventricular diastolic function of patients with type 2 diabetic mellitus with chronic heart failure

Fumitaka Soga, Hidekazu Tanaka, Kazuhiro Tatsumi, Yasuhide Mochizuki, Hiroyuki Sano, Hiromi Toki, Kensuke Matsumoto, Junya Shite, Hideyuki Takaoka, Tomofumi Doi, Ken-ichi Hirata

Open Access Original investigation

Rising plasminogen activator inhibitor-1 and hypoadiponectinemia characterize the cardiometabolic biomarker profile of women with recent gestational diabetes

Sadia Mehmood, Chang Ye, Philip W. Connelly, Anthony J. Hanley, Bernard Zinman, Ravi Retnakaran

Open Access Review

Perivascular adipose tissue (PVAT) in atherosclerosis: a double-edged sword

Xiao-Yan Qi, Shun-Lin Qu, Wen-Hao Xiong, Oren Rom, Lin Chang, Zhi-Sheng Jiang

Open Access Original investigation

Impact of type 2 diabetes mellitus in the utilization and in-hospital outcomes of surgical aortic valve replacement in Spain (2001–2015)

Ana López-de-Andrés, Napoleon Perez-Farinos, Javier de Miguel-Díez, Valentín Hernández-Barrera, Manuel Méndez-Bailón, José M. de Miguel-Yanes, Rodrigo Jiménez-García

Open Access Original investigation

Hyperglycemia and risk of ventricular tachycardia among patients hospitalized with acute myocardial infarction

Hoang V. Tran, Joel M. Gore, Chad E. Darling, Arlene S. Ash, Catarina I. Kiefe, Robert J. Goldberg

Open Access Original investigation

Cardiac resynchronization therapy with a defibrillator (CRTd) in failing heart patients with type 2 diabetes mellitus and treated by glucagon-like peptide 1 receptor agonists (GLP-1 RA) therapy vs. conventional hypoglycemic drugs: arrhythmic burden, hospitalizations for heart failure, and CRTd responders rate

Celestino Sardu, Pasquale Paolisso, Cosimo Sacra, Matteo Santamaria, Claudio de Lucia, Antonio Ruocco, Ciro Mauro, Giuseppe Paolisso, Maria Rosaria Rizzo, Michelangela Barbieri, Raffaele Marfella

Open Access Review

Lower extremity arterial disease in patients with diabetes: a contemporary narrative review

Mathilde Nativel, Louis Potier, Laure Alexandre, Laurence Baillet-Blanco, Eric Ducasse, Gilberto Velho, Michel Marre, Ronan Roussel, Vincent Rigalleau, Kamel Mohammedi

Open Access Original investigation

Left ventricular subclinical myocardial dysfunction in uncomplicated type 2 diabetes mellitus is associated with impaired myocardial perfusion: a contrast-enhanced cardiovascular magnetic resonance study

Xi Liu, Zhi-gang Yang, Yue Gao, Lin-jun Xie, Li Jiang, Bi-yue Hu, Kai-yue Diao, Ke Shi, Hua-yan Xu, Meng-ting Shen, Yan Ren, Ying-kun Guo

Open Access Original investigation

Impact of intravenous exenatide infusion for perioperative blood glucose control on myocardial ischemia-reperfusion injuries after coronary artery bypass graft surgery: sub study of the phase II/III ExSTRESS randomized trial

Guillaume Besch, Andrea Perrotti, Lucie Salomon du Mont, Marc Puyraveau, Xavier Ben-Said, Maude Baltres, Benoit Barrucand, Guillaume Flicoteaux, Lucie Vettoretti, Emmanuel Samain, Sidney Chocron, Sebastien Pili-Floury

Open Access Original investigation

Platelet activity and hypercoagulation in type 2 diabetes

Lesha Pretorius, Greig J. A. Thomson, Rozanne C. M. Adams, Theo A. Nell, Willem A. Laubscher, Etheresia Pretorius

Open Access Original investigation

The negative effect of ANGPTL8 on HDL-mediated cholesterol efflux capacity

Mengdie Luo, Ziyu Zhang, Yani Peng, Shuai Wang, Daoquan Peng

Open Access Original investigation

Correlations between serum concentration of three bone-derived factors and obesity and visceral fat accumulation in a cohort of middle aged men and women

Yiting Xu, Xiaojing Ma, Xiaoping Pan, Xingxing He, Yunfeng Xiao, Yuqian Bao

Open Access Original investigation

A SGLT2 inhibitor dapagliflozin suppresses prolonged ventricular-repolarization through augmentation of mitochondrial function in insulin-resistant metabolic syndrome rats

Aysegul Durak, Yusuf Olgar, Sinan Degirmenci, Erman Akkus, Erkan Tuncay, Belma Turan

Open Access Commentary

Unrecognised cardiovascular disease in type 2 diabetes: is it time to act earlier?

Guntram Schernthaner, Chaim Lotan, Elina Baltadzhieva-Trendafilova, Jonas Ceponis, Martin Clodi, Kristine Ducena, Eva Goncalvesova, Cristian Guja, Marek Honka, Andrej Janež, Nebojša Lalić, Roger Lehmann, Noémi Nyolczas, Priit Pauklin, Andrzej Rynkiewicz, Igor Sergienko, Lea Smirčić Duvnjak

Open Access Original investigation

Polyhedrocytes in blood clots of type 2 diabetic patients with high cardiovascular risk: association with glycemia, oxidative stress and platelet activation

Grzegorz Gajos, Aleksander Siniarski, Joanna Natorska, Michał Ząbczyk, Jakub Siudut, Krzysztof Piotr Malinowski, Renata Gołębiowska-Wiatrak, Paweł Rostoff, Anetta Undas

Open Access Original investigation

Prevalence and in-hospital outcomes of diabetes among patients with acute coronary syndrome in China: findings from the Improving Care for Cardiovascular Disease in China-Acute Coronary Syndrome Project

Mengge Zhou, Jing Liu, Yongchen Hao, Jun Liu, Yong Huo, Sidney C. Smith Jr., Junbo Ge, Changsheng Ma, Yaling Han, Gregg C. Fonarow, Kathryn A. Taubert, Louise Morgan, Na Yang, Yueyan Xing, Dong Zhao

Open Access Commentary

Does glucagon have a positive inotropic effect in the human heart?

Jesus Hernández-Cascales

Open Access Original investigation

Increased glycated albumin and decreased esRAGE levels in serum are related to negative coronary artery remodeling in patients with type 2 diabetes: an Intravascular ultrasound study

Run Du, Rui Yan Zhang, Lin Lu, Ying Shen, Li Jin Pu, Zheng Bin Zhu, Qi Zhang, Jian Hu, Zhen Kun Yang, Feng Hua Ding, Jian Sheng Zhang, Wei Feng Shen

Open Access Original investigation

Vascular complications in patients with type 2 diabetes: prevalence and associated factors in 38 countries (the DISCOVER study program)

Mikhail Kosiborod, Marilia B. Gomes, Antonio Nicolucci, Stuart Pocock, Wolfgang Rathmann, Marina V. Shestakova, Hirotaka Watada, Iichiro Shimomura, Hungta Chen, Javier Cid-Ruzafa, Peter Fenici, Niklas Hammar, Filip Surmont, Fengming Tang, Kamlesh Khunti

Open Access Original investigation

Impact of type 2 diabetes mellitus on short- and long-term mortality after coronary artery bypass surgery

Alexander Kogan, Eilon Ram, Shany Levin, Enrique Z. Fisman, Alexander Tenenbaum, Ehud Raanani, Leonid Sternik

Open Access Original investigation

Thrombus aspiration in hyperglycemic ST-elevation myocardial infarction (STEMI) patients: clinical outcomes at 1-year follow-up

Celestino Sardu, Michelangela Barbieri, Maria Luisa Balestrieri, Mario Siniscalchi, Pasquale Paolisso, Paolo Calabrò, Fabio Minicucci, Giuseppe Signoriello, Michele Portoghese, Pasquale Mone, Davide D’Andrea, Felice Gragnano, Alessandro Bellis, Ciro Mauro, Giuseppe Paolisso, Maria Rosaria Rizzo, Raffaele Marfella

Open Access Original investigation

Empagliflozin on top of metformin treatment improves arterial function in patients with type 1 diabetes mellitus

Mojca Lunder, Miodrag Janić, Miha Japelj, Andrej Juretič, Andrej Janež, Mišo Šabovič

Open Access Original investigation

Cognitive function in adolescence and the risk for premature diabetes and cardiovascular mortality in adulthood

Gilad Twig, Amir Tirosh, Estela Derazne, Ziona Haklai, Nehama Goldberger, Arnon Afek, Hertzel C. Gerstein, Jeremy D. Kark, Tali Cukierman-Yaffe

Open Access Original investigation

Associations between epicardial adipose tissue, subclinical atherosclerosis and high-density lipoprotein composition in type 1 diabetes

Cristina Colom, David Viladés, Montserrat Pérez-Cuellar, Rubén Leta, Andrea Rivas-Urbina, Gemma Carreras, Jordi Ordóñez-Llanos, Antonio Pérez, Jose Luis Sánchez-Quesada

Open Access Review

GLP-1RAs in type 2 diabetes: mechanisms that underlie cardiovascular effects and overview of cardiovascular outcome data

Andrei C. Sposito, Otávio Berwanger, Luiz Sérgio F. de Carvalho, José Francisco Kerr Saraiva

Open Access Original investigation

Low cholesterol efflux capacity and abnormal lipoprotein particles in youth with type 1 diabetes: a case control study

Evgenia Gourgari, Martin P. Playford, Umberto Campia, Amit K. Dey, Fran Cogen, Stephanie Gubb-Weiser, Mihriye Mete, Sameer Desale, Maureen Sampson, Allen Taylor, Kristina I. Rother, Alan T. Remaley, Nehal N. Mehta

Open Access Correction

Correction to: Thrombus aspiration in hyperglycemic ST-elevation myocardial infarction (STEMI) patients: clinical outcomes at 1-year follow-up

Celestino Sardu, Michelangela Barbieri, Maria Luisa Balestrieri, Mario Siniscalchi, Pasquale Paolisso, Paolo Calabrò, Fabio Minicucci, Giuseppe Signoriello, Michele Portoghese, Pasquale Mone, Davide D’Andrea, Felice Gragnano, Alessandro Bellis, Ciro Mauro, Giuseppe Paolisso, Maria Rosaria Rizzo, Raffaele Marfella

Open Access Original investigation

Alogliptin prevents diastolic dysfunction and preserves left ventricular mitochondrial function in diabetic rabbits

Xiaowei Zhang, Zhiwei Zhang, Yajuan Yang, Ya Suo, Ruimeng Liu, Jiuchun Qiu, Yungang Zhao, Ning Jiang, Changle Liu, Gary Tse, Guangping Li, Tong Liu

Open Access Original investigation

A 23-year study of mortality and development of co-morbidities in patients with obesity undergoing bariatric surgery (laparoscopic gastric banding) in comparison with medical treatment of obesity

Antonio E. Pontiroli, Ahmed S. Zakaria, Marco Fanchini, Chiara Osio, Elena Tagliabue, Giancarlo Micheletto, Alessandro Saibene, Franco Folli

Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin
Prof. Florian Limbourg
Prof. Anoop Chauhan
Developed by: Springer Medicine
Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine
Webinar | 06-02-2024 | 20:00 (CET)

Mastering chronic pancreatitis pain: A multidisciplinary approach and practical solutions

Severe pain is the most common symptom of chronic pancreatitis. In this webinar, experts share the latest insights in pain management for chronic pancreatitis patients. Experts from a range of disciplines discuss pertinent cases and provide practical suggestions for use within clinical practice.

Sponsored by: Viatris

Developed by: Springer Healthcare