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Cancer Immunology, Immunotherapy

Issue 10/2019

Content (16 Articles)

Open Access Lymphoma Original Article

Presence of T cells directed against CD20-derived peptides in healthy individuals and lymphoma patients

Benoit Milcent, Nathalie Josseaume, Quentin Riller, Ilenia Giglioli, Emilia Rabia, Claire Deligne, Jean-Baptiste Latouche, Mohamad Hamieh, Alexandre Couture, Olivier Toutirais, Yu-Chun Lone, Raphaël Jeger-Madiot, Stéphanie Graff-Dubois, Sandy Amorim, Pascale Loiseau, Antoine Toubert, Pauline Brice, Catherine Thieblemont, Jean-Luc Teillaud, Sophie Sibéril

Desmoid tumors display a strong immune infiltration at the tumor margins and no PD-L1-driven immune suppression

Vasiliki Siozopoulou, Elly Marcq, Julie Jacobs, Karen Zwaenepoel, Christophe Hermans, Jantine Brauns, Siegrid Pauwels, Clément Huysentruyt, Martin Lammens, Johan Somville, Evelien Smits, Patrick Pauwels

Kidney Cancer Original Article

Peripheral changes in immune cell populations and soluble mediators after anti-PD-1 therapy in non-small cell lung cancer and renal cell carcinoma patients

Estefanía Paula Juliá, Pablo Mandó, Manglio Miguel Rizzo, Gerardo Rubén Cueto, Florencia Tsou, Romina Luca, Carmen Pupareli, Alicia Inés Bravo, Walter Astorino, José Mordoh, Claudio Martín, Estrella Mariel Levy

Original Article

ANTXR1 (TEM8) overexpression in gastric adenocarcinoma makes the protein a potential target of immunotherapy

Masoud Sotoudeh, Ramin Shakeri, Sanford M. Dawsey, Bahareh Sharififard, Naser Ahmadbeigi, Mahmood Naderi

Open Access Prostate Cancer Original Article

The BRCA2 mutation status shapes the immune phenotype of prostate cancer

Maximilian Jenzer, Peter Keß, Cathleen Nientiedt, Volker Endris, Maximilian Kippenberger, Jonas Leichsenring, Fabian Stögbauer, Josh Haimes, Skyler Mishkin, Brian Kudlow, Adam Kaczorowski, Stefanie Zschäbitz, Anna-Lena Volckmar, Holger Sültmann, Dirk Jäger, Anette Duensing, Peter Schirmacher, Markus Hohenfellner, Carsten Grüllich, Albrecht Stenzinger, Stefan Duensing

Vaccination Original Article

Gastrin vaccine improves response to immune checkpoint antibody in murine pancreatic cancer by altering the tumor microenvironment

Nicholas Osborne, Rebecca Sundseth, Julian Burks, Hong Cao, Xunxian Liu, Alexander H. Kroemer, Lynda Sutton, Allen Cato, Jill P. Smith

Checkpoint Inhibitors Original Article

PTPN3 expressed in activated T lymphocytes is a candidate for a non-antibody-type immune checkpoint inhibitor

Akiko Fujimura, Kazunori Nakayama, Akira Imaizumi, Makoto Kawamoto, Yasuhiro Oyama, Shu Ichimiya, Masayo Umebayashi, Norihiro Koya, Takashi Morisaki, Takashi Nakagawa, Hideya Onishi

Breast Cancer Focussed Research Review

The role of immune infiltrates as prognostic biomarkers in patients with breast cancer

Constantin N. Baxevanis, Michael Sofopoulos, Sotirios P. Fortis, Sonia A. Perez

Open Access Melanoma Focussed Research Review

Unlocking the therapeutic potential of primary tumor-draining lymph nodes

Jossie Rotman, Bas D. Koster, Ekaterina S. Jordanova, A. Marijne Heeren, Tanja D. de Gruijl

Interferon Focussed Research Review

Tumor-induced escape mechanisms and their association with resistance to checkpoint inhibitor therapy

Michael Friedrich, Simon Jasinski-Bergner, Maria-Filothei Lazaridou, Karthikeyan Subbarayan, Chiara Massa, Sandy Tretbar, Anja Mueller, Diana Handke, Katharina Biehl, Jürgen Bukur, Marco Donia, Ofer Mandelboim, Barbara Seliger

Focussed Research Review

T cell engineering for adoptive T cell therapy: safety and receptor avidity

Elvira D’Ippolito, Kilian Schober, Magdalena Nauerth, Dirk H. Busch

Open Access Tumor Lysis Syndrome Focussed Research Review

Conventional CARs versus modular CARs

Anja Feldmann, Claudia Arndt, Stefanie Koristka, Nicole Berndt, Ralf Bergmann, Michael P. Bachmann

Webinar | 19-02-2024 | 17:30 (CET)

Keynote webinar | Spotlight on antibody–drug conjugates in cancer

Antibody–drug conjugates (ADCs) are novel agents that have shown promise across multiple tumor types. Explore the current landscape of ADCs in breast and lung cancer with our experts, and gain insights into the mechanism of action, key clinical trials data, existing challenges, and future directions.

Dr. Véronique Diéras
Prof. Fabrice Barlesi
Developed by: Springer Medicine