Skip to main content
Top
Published in: Journal of Cardiothoracic Surgery 1/2021

Open Access 01-12-2021 | CABG | Research article

Patient and hospital factors associated with 30-day readmissions after coronary artery bypass graft (CABG) surgery: a systematic review and meta-analysis

Authors: Md Shajedur Rahman Shawon, Michael Odutola, Michael O. Falster, Louisa R. Jorm

Published in: Journal of Cardiothoracic Surgery | Issue 1/2021

Login to get access

Abstract

Background

Readmission after coronary artery bypass graft (CABG) surgery is associated with adverse outcomes and significant healthcare costs, and 30-day readmission rate is considered as a key indicator of the quality of care. This study aims to: quantify rates of readmission within 30 days of CABG surgery; explore the causes of readmissions; and investigate how patient- and hospital-level factors influence readmission.

Methods

We conducted systematic searches (until June 2020) of PubMed and Embase databases to retrieve observational studies that investigated readmission after CABG. Random effect meta-analysis was used to estimate rates and predictors of 30-day post-CABG readmission.

Results

In total, 53 studies meeting inclusion criteria were identified, including 8,937,457 CABG patients. The pooled 30-day readmission rate was 12.9% (95% CI: 11.3–14.4%). The most frequently reported underlying causes of 30-day readmissions were infection and sepsis (range: 6.9–28.6%), cardiac arrythmia (4.5–26.7%), congestive heart failure (5.8–15.7%), respiratory complications (1–20%) and pleural effusion (0.4–22.5%). Individual factors including age (OR per 10-year increase 1.12 [95% CI: 1.04–1.20]), female sex (OR 1.29 [1.25–1.34]), non-White race (OR 1.15 [1.10–1.21]), not having private insurance (OR 1.39 [1.27–1.51]) and various comorbidities were strongly associated with 30-day readmission rates, whereas associations with hospital factors including hospital CABG volume, surgeon CABG volume, hospital size, hospital quality and teaching status were inconsistent.

Conclusions

Nearly 1 in 8 CABG patients are readmitted within 30 days and the majority of these are readmitted for noncardiac causes. Readmission rates are strongly influenced by patients’ demographic and clinical characteristics, but not by broadly defined hospital characteristics.
Appendix
Available only for authorised users
Literature
9.
go back to reference Commission MPA. Report to the congress: promoting greater efficiency in Medicare: Medicare payment advisory commission (MedPAC); 2007. Commission MPA. Report to the congress: promoting greater efficiency in Medicare: Medicare payment advisory commission (MedPAC); 2007.
12.
go back to reference Angraal S, Khera R, Wang Y, Lu Y, Jean R, Dreyer RP, et al. Sex and race differences in the utilization and outcomes of coronary artery bypass grafting among medicare beneficiaries, 1999–2014. J Am Heart Assoc. 2018;7(14):e009014.CrossRefPubMedPubMedCentral Angraal S, Khera R, Wang Y, Lu Y, Jean R, Dreyer RP, et al. Sex and race differences in the utilization and outcomes of coronary artery bypass grafting among medicare beneficiaries, 1999–2014. J Am Heart Assoc. 2018;7(14):e009014.CrossRefPubMedPubMedCentral
22.
go back to reference Auerbach AD, Hilton JF, Maselli J, Pekow PS, Rothberg MB, Lindenauer PK. Shop for quality or volume? Volume, quality, and outcomes of coronary artery bypass surgery. Ann Intern Med. 2009;150(10):696–704+W-123.CrossRefPubMedPubMedCentral Auerbach AD, Hilton JF, Maselli J, Pekow PS, Rothberg MB, Lindenauer PK. Shop for quality or volume? Volume, quality, and outcomes of coronary artery bypass surgery. Ann Intern Med. 2009;150(10):696–704+W-123.CrossRefPubMedPubMedCentral
29.
go back to reference Chan PG, Sultan I, Gleason TG, Wang Y, Navid F, Thoma F, et al. Contemporary outcomes of coronary artery bypass grafting in obese patients. J Cardiac Surg. 2020;35:549.CrossRef Chan PG, Sultan I, Gleason TG, Wang Y, Navid F, Thoma F, et al. Contemporary outcomes of coronary artery bypass grafting in obese patients. J Cardiac Surg. 2020;35:549.CrossRef
30.
go back to reference Chen JC, Shaw JD, Ma Y, Rhoads KF. The role of the hospital and health care system characteristics in readmissions after major surgery in California. Surgery (United States). 2016;159(2):381–8. Chen JC, Shaw JD, Ma Y, Rhoads KF. The role of the hospital and health care system characteristics in readmissions after major surgery in California. Surgery (United States). 2016;159(2):381–8.
34.
go back to reference Fanari Z, Elliott D, Russo C, Kolm P, Weintraub W. Predicting readmission risk following coronary artery bypass surgery at the time of admission. J Am Coll Cardiol. 2017;69(11 Supplement 1):2504.CrossRef Fanari Z, Elliott D, Russo C, Kolm P, Weintraub W. Predicting readmission risk following coronary artery bypass surgery at the time of admission. J Am Coll Cardiol. 2017;69(11 Supplement 1):2504.CrossRef
35.
go back to reference Feng TR, White RS, Gaber-Baylis LK, Turnbull ZA, Rong LQ. Coronary artery bypass graft readmission rates and risk factors - A retrospective cohort study. Int J Surg. 2018;Part A. 54:7–17.CrossRef Feng TR, White RS, Gaber-Baylis LK, Turnbull ZA, Rong LQ. Coronary artery bypass graft readmission rates and risk factors - A retrospective cohort study. Int J Surg. 2018;Part A. 54:7–17.CrossRef
41.
go back to reference Hirji SA, Percy ED, Zogg CK, Vaduganathan M, Kiehm S, Pelletier M, et al. Thirty-day non-index readmissions and clinical outcomes following cardiac surgery. Ann Thorac Surg. 2020;110:484.CrossRefPubMedPubMedCentral Hirji SA, Percy ED, Zogg CK, Vaduganathan M, Kiehm S, Pelletier M, et al. Thirty-day non-index readmissions and clinical outcomes following cardiac surgery. Ann Thorac Surg. 2020;110:484.CrossRefPubMedPubMedCentral
45.
go back to reference Koochemeshki V, Salmanzadeh HR, Sayyadi H, Amestejani M, Ardabili SS. The effect of diabetes mellitus on short term mortality and morbidity after isolated coronary artery bypass grafting surgery. Int Cardiovasc Res J. 2013;7(2):41–5.PubMedPubMedCentral Koochemeshki V, Salmanzadeh HR, Sayyadi H, Amestejani M, Ardabili SS. The effect of diabetes mellitus on short term mortality and morbidity after isolated coronary artery bypass grafting surgery. Int Cardiovasc Res J. 2013;7(2):41–5.PubMedPubMedCentral
46.
go back to reference Lancey R, Kurlansky P, Argenziano M, Coady M, Dunton R, Greelish J, et al. Uniform standards do not apply to readmission following coronary artery bypass surgery: A multi-institutional study. J Thorac Cardiovasc Surg. 2015;149(3):850–7.e1.CrossRefPubMed Lancey R, Kurlansky P, Argenziano M, Coady M, Dunton R, Greelish J, et al. Uniform standards do not apply to readmission following coronary artery bypass surgery: A multi-institutional study. J Thorac Cardiovasc Surg. 2015;149(3):850–7.e1.CrossRefPubMed
49.
go back to reference Li Z, Armstrong EJ, Amsterdam E, Young JN, Parker J. Contemporary outcomes of coronary artery bypass grafting among patients with insulin treated and non-insulin treated diabetes. J Am Coll Cardiol. 2015;65(10):A1646.CrossRef Li Z, Armstrong EJ, Amsterdam E, Young JN, Parker J. Contemporary outcomes of coronary artery bypass grafting among patients with insulin treated and non-insulin treated diabetes. J Am Coll Cardiol. 2015;65(10):A1646.CrossRef
50.
go back to reference Narain A, Kwok CS, Lea A, Ridley P, Warwick R, Manorekang R, et al. Early readmissions after isolated coronary artery bypass grafting. Int J Clin Pract. 2019;73(4):e13319.CrossRefPubMed Narain A, Kwok CS, Lea A, Ridley P, Warwick R, Manorekang R, et al. Early readmissions after isolated coronary artery bypass grafting. Int J Clin Pract. 2019;73(4):e13319.CrossRefPubMed
55.
go back to reference Saab S, Noureddine S, Dumit NY. Readmission rates and emergency department visits after coronary artery bypass graft surgery and related factors. J Med Liban. 2013;61(3):155–60.PubMed Saab S, Noureddine S, Dumit NY. Readmission rates and emergency department visits after coronary artery bypass graft surgery and related factors. J Med Liban. 2013;61(3):155–60.PubMed
68.
go back to reference Fingar KR, Barrett ML, Jiang HJ. A comparison of all-cause 7-day and 30-day readmissions, 2014: Statistical Brief #230. 2017 Oct. In: Healthcare Cost and Utilization Project (HCUP) Statistical Briefs [Internet]. Rockville (MD): Agency for Healthcare Research and Quality (US); 2006. Fingar KR, Barrett ML, Jiang HJ. A comparison of all-cause 7-day and 30-day readmissions, 2014: Statistical Brief #230. 2017 Oct. In: Healthcare Cost and Utilization Project (HCUP) Statistical Briefs [Internet]. Rockville (MD): Agency for Healthcare Research and Quality (US); 2006.
Metadata
Title
Patient and hospital factors associated with 30-day readmissions after coronary artery bypass graft (CABG) surgery: a systematic review and meta-analysis
Authors
Md Shajedur Rahman Shawon
Michael Odutola
Michael O. Falster
Louisa R. Jorm
Publication date
01-12-2021
Publisher
BioMed Central
Keywords
CABG
CABG
Published in
Journal of Cardiothoracic Surgery / Issue 1/2021
Electronic ISSN: 1749-8090
DOI
https://doi.org/10.1186/s13019-021-01556-1

Other articles of this Issue 1/2021

Journal of Cardiothoracic Surgery 1/2021 Go to the issue