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Journal of Cardiothoracic Surgery

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Open Access 01-12-2021 | Angiography | Research article

Percutaneous transluminal stenting for superior vena cava syndrome caused by malignant tumors: a single-center retrospective study

Authors: Haitao Liu, Yahua Li, Yang Wang, Lei Yan, Pengli Zhou, Xinwei Han

Published in: Journal of Cardiothoracic Surgery | Issue 1/2021

Abstract

Objectives

To evaluate the efficacy of percutaneous stent placement in the treatment of superior vena cava syndrome caused by malignant tumors.

Methods

We retrospectively analyzed the clinical data of 32 patients with superior vena cava syndrome who underwent percutaneous endovascular stent treatment in our department from 2015 to 2019 due to malignant tumors and summarized the patient’s sex, age, tumor type, endovascular treatment plan, complications and postoperative follow-up.

Results

All patients successfully underwent percutaneous intraluminal stent placement with digital subtraction angiography (DSA). Thirty-seven endovascular stents were implanted in 32 patients, including 21 Eluminexx stents, 12 Wallstent stents and 4 covered stents. The technical success rate was 100%, and there were no serious surgery-related complications. The remission rate of clinical symptoms was 53.1% (17/32) at 24 h and 84.4% (27/32) at 48 h. After 48 h, the symptoms of the remaining patients were slowly relieved, and the symptom relief rate was 100% at 7 days. The follow-up period was 1.5–24 months, with an average follow-up period of 6.5 months. During the follow-up, 3 patients had restenosis and 1 patient had secondary thrombosis in the stent. Their symptoms were relieved after the second treatment.

Conclusion

For superior vena cava syndrome caused by malignant tumors, percutaneous endoluminal stent therapy can quickly and effectively relieve the clinical symptoms of patients, and the incidence of complications is low.

Sfyroeras GS, Antonopoulos CN, Mantas G, Moulakakis KG, Kakisis JD, Brountzos E, et al. A review of open and endovascular treatment of superior vena cava syndrome of benign aetiology. Eur J Vasc Endovasc Surg. 2017;53(2):238–54. https://doi.org/10.1016/j.ejvs.2016.11.013.CrossRefPubMed

Breault S, Doenz F, Jouannic AM, Qanadli SD. Percutaneous endovascular management of chronic superior vena cava syndrome of benign causes:long-term follow-up. Eur Radiol. 2017;27(1):97–104. https://doi.org/10.1007/s00330-016-4354-y.CrossRefPubMed

Wu TY, Wu CK, Chen YY, Lin CH. Comparison of percutaneous transluminal angioplasty with stenting for treatment of central venous stenosis or occlusion in hemodialysis patients: a systematic review and meta-analysis. Cardiovasc Intervent Radiol. 2020;43(4):525–40.CrossRef

Kalra M, Sen I, Gloviczki P. Endovenous and operative treatment of superior vena cava syndrome. Surg Clin North Am. 2018;98(2):321–35. https://doi.org/10.1016/j.suc.2017.11.013.CrossRefPubMed

Maurizi G, Poggi C, D'Andrilli A, Vanni C, Ciccone AM, Ibrahim M, et al. Superior vena cava replacement for thymic malignancies. Ann Thorac Surg. 2019;107(2):386–92. https://doi.org/10.1016/j.athoracsur.2018.08.060.CrossRefPubMed

Sato H, Soh J, Hotta K, Katsui K, Kanazawa S, Kiura K, Toyooka S. Is surgery after chemoradiotherapy feasible in lung cancer patients with superior vena cava invasion? Ann Thorac Cardiovasc Surg. 2018;24(3):131–8. https://doi.org/10.5761/atcs.oa.18-00027.CrossRefPubMedPubMedCentral

Hinton J, Cerra-Franco A, Shiue K, Shea L, Aaron V, Billows G, al-Hader A, Lautenschlaeger T. Superior vena cava syndrome in a patient with locally advanced lung cancer with good response to definitive chemoradiation: a case report. J Med Case Rep. 2018;12(1):301. https://doi.org/10.1186/s13256-018-1843-4.CrossRefPubMedPubMedCentral

Lanciego C, Chacón JL, Julián A, Andrade J, López L, Martinez B, et al. Stenting as first option for endovascular treatment of malignant superior vena cava syndrome. AJR Am J Roentgenol. 2001;177(3):585–93. https://doi.org/10.2214/ajr.177.3.1770585.CrossRefPubMed

Straka C, Ying J, Kong FM, Willey CD, Kaminski J, Kim DW. Review of evolving etiologies, implications and treatment strategies for the superior vena cava syndrome. Springerplus. 2016;5(1):229. https://doi.org/10.1186/s40064-016-1900-7.CrossRefPubMedPubMedCentral

10.

Niu S, Xu YS, Cheng L, Cao C. Stent insertion for malignant superior vena cava syndrome: effectiveness and long-term outcome. Radiol Med. 2017;122(8):633–8. https://doi.org/10.1007/s11547-017-0767-1.CrossRefPubMed

11.

Picquet J, Blin V, Dussaussoy C, Jousset Y, Papon X, Enon B. Surgical reconstruction of the superior vena cava system: indications and results. Surgery. 2009;145(1):93–9. https://doi.org/10.1016/j.surg.2008.08.003.CrossRefPubMed

12.

Kuo TT, Chen PL, Shih CC, Chen IM. Endovascular stenting for end-stage lung cancer patients with superior vena cava syndrome post first-line treatments-a single-center experience and literature review. J Chin Med Assoc. 2017;80(8):482–6. https://doi.org/10.1016/j.jcma.2017.04.005.CrossRefPubMed

13.

Wei S, Liu J, Li X, Song Z, Dong M, Zhao H, Zhao Q, Chen G, Chen J. A retrospective stenting study on superior vena cava syndrome caused by lung cancer. Thorac Cancer. 2020;11(7):1835–9. https://doi.org/10.1111/1759-7714.13461.CrossRefPubMedPubMedCentral

14.

Mokry T, Bellemann N, Sommer CM, Heussel CP, Bozorgmehr F, Gnutzmann D, et al. Retrospective study in 23 patients of the self-expanding sinus-XL stent for treatment of malignant superior vena cava obstruction caused by non-small cell lung cancer. J Vasc Interv Radiol. 2015;26(3):357–65.CrossRef

15.

Maleux G, Gillardin P, Fieuws S, Heye S, Vaninbroukx J, Nackaerts K. Large-bore nitinol stents for malignant superior vena cava syndrome: factors influencing outcome. AJR Am J Roentgenol. 2013;201(3):667–74. https://doi.org/10.2214/AJR.12.9582.CrossRefPubMed

16.

Fagedet D, Thony F, Timsit JF, Rodiere M, Monnin-Bares V, Ferretti GR, et al. Endovascular treatment of malignant superior vena cava syndrome: results and predictive factors of clinical efficacy. Cardiovasc Intervent Radiol. 2013;36(1):140–9.CrossRef

17.

Gwon DI, Ko GY, Kim JH, Shin JH, Yoon HK, Sung KB. Malignant superior vena cava syndrome: a comparative cohort study of treatment with covered stents versus uncovered stents. Radiology. 2013;266(3):979–87. https://doi.org/10.1148/radiol.12120517.CrossRefPubMed

18.

Ganeshan A, Hon LQ, Warakaulle DR, Morgan R, Uberoi R. Superior vena caval stenting for SVC obstruction: current status. Eur J Radiol. 2009;71(2):343–9. https://doi.org/10.1016/j.ejrad.2008.04.014.CrossRefPubMed

19.

Andersen PE, Duvnjak S. Palliative treatment of superior vena cava syndrome with nitinol stents. Int J Angiol. 2014;23(4):255–62.CrossRef

20.

Takahara Y, Ishige Y, Shionoya I, Fujimoto Y, Oikawa T, Mizuno S. Second SVC stent treatment for tumour ingrowth. Respirol Case Rep. 2020;8(6):e00619. https://doi.org/10.1002/rcr2.619.CrossRefPubMedPubMedCentral

Title: Percutaneous transluminal stenting for superior vena cava syndrome caused by malignant tumors: a single-center retrospective study
Authors: Haitao Liu
Yahua Li
Yang Wang
Lei Yan
Pengli Zhou
Xinwei Han
Publication date: 01-12-2021
Publisher: BioMed Central
Keyword: Angiography
Published in: Journal of Cardiothoracic Surgery / Issue 1/2021
Electronic ISSN: 1749-8090
DOI: https://doi.org/10.1186/s13019-021-01418-w

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Percutaneous transluminal stenting for superior vena cava syndrome caused by malignant tumors: a single-center retrospective study

Abstract

Objectives

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Objectives

Methods

Results

Conclusion

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