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Published in: BMC Pulmonary Medicine 1/2021

Open Access 01-12-2021 | Bronchial Asthma | Research

Quality of life and asthma control in pregnant women with asthma

Authors: Nasrin Fazel, Michael Kundi, Erika Jensen-Jarolim, Isabella Maria Pali-Schöll, Asghar Kazemzadeh, Habibollah Esmaily, Mojtaba Fattahi Abdizadeh, Roya Akbarzadeh, Raheleh Ahmadi, Hossain Jabbari

Published in: BMC Pulmonary Medicine | Issue 1/2021

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Abstract

Background

Asthma is the most commonly occurring respiratory illness during pregnancy. Associations with complications of pregnancy and adverse perinatal outcome have been established. However, little is known about quality of life (QoL) in pregnant women with asthma and how it relates to asthma control particularly for Iran.

Objective

To determine the relationship between asthma related QoL and asthma control and severity.

Methods

We conducted a prospective study in pregnant women with asthma. We used the Asthma Control Questionnaire and the Asthma Quality of Life Questionnaire (AQLQ) and the guidelines of the Global Initiative for Asthma for assessment of asthma severity.

Results

Among 1603 pregnant women, 34 were diagnosed with asthma. Of these 13 had intermittent, 10 mild, 8 moderate and 3 severe persistent asthma. There was a significant decrease of QoL with poorer asthma control (p = 0.014). This decline could be due to limitations of activity in those with poorer asthma control, which is underlined by the significant decline of QoL with increasing asthma severity (p = 0.024).

Conclusion

Although the majority of pregnant women with asthma had a favorable score in AQLQ, reduced QoL was related to increased asthma severity and poor asthma control. This underlines the importance of controlling asthma during pregnancy not only for the prevention of adverse pregnancy outcomes but also for the preservation of QoL.
Literature
1.
go back to reference Yektatalab S, Ansarfard F. The relationship between mental health and quality of life in patients with asthma. Psychiatr Nurs. 2014;2(1):64–72. Yektatalab S, Ansarfard F. The relationship between mental health and quality of life in patients with asthma. Psychiatr Nurs. 2014;2(1):64–72.
3.
go back to reference Chung KD, Demissie K, Rhoads GG. Asthma in pregnancy—its relationship with race, insurance, maternal education, and prenatal care utilization. J Natl Med Assoc. 2004;96(11):1414.PubMedPubMedCentral Chung KD, Demissie K, Rhoads GG. Asthma in pregnancy—its relationship with race, insurance, maternal education, and prenatal care utilization. J Natl Med Assoc. 2004;96(11):1414.PubMedPubMedCentral
4.
go back to reference Katz O, Sheiner E. Asthma and pregnancy: a review of two decades. Expert Rev Respir Med. 2008;2(1):97–107.CrossRef Katz O, Sheiner E. Asthma and pregnancy: a review of two decades. Expert Rev Respir Med. 2008;2(1):97–107.CrossRef
5.
go back to reference Shofany C. Quality of life among chronic disease patients. Nurs Care Open Access J. 2017;4(2):385–94. Shofany C. Quality of life among chronic disease patients. Nurs Care Open Access J. 2017;4(2):385–94.
6.
go back to reference Wijnhoven HA, Kriegsman DM, Hesselink AE, Penninx BW, De Haan M. Determinants of different dimensions of disease severity in asthma and COPD: pulmonary function and health-related quality of life. Chest. 2001;119(4):1034–42.CrossRef Wijnhoven HA, Kriegsman DM, Hesselink AE, Penninx BW, De Haan M. Determinants of different dimensions of disease severity in asthma and COPD: pulmonary function and health-related quality of life. Chest. 2001;119(4):1034–42.CrossRef
7.
go back to reference Schatz M, Dombrowski MP, Wise R, Lai Y, Landon M, Newman RB, et al. The relationship of asthma-specific quality of life during pregnancy to subsequent asthma and perinatal morbidity. J Asthma. 2010;47(1):46–50.CrossRef Schatz M, Dombrowski MP, Wise R, Lai Y, Landon M, Newman RB, et al. The relationship of asthma-specific quality of life during pregnancy to subsequent asthma and perinatal morbidity. J Asthma. 2010;47(1):46–50.CrossRef
8.
go back to reference Basaran S, Guler-Uysal F, Ergen N, Seydaoglu G, Bingol-Karakoç G, Ufuk AD. Effects of physical exercise on quality of life, exercise capacity and pulmonary function in children with asthma. J Rehabil Med. 2006;38(2):130–5.CrossRef Basaran S, Guler-Uysal F, Ergen N, Seydaoglu G, Bingol-Karakoç G, Ufuk AD. Effects of physical exercise on quality of life, exercise capacity and pulmonary function in children with asthma. J Rehabil Med. 2006;38(2):130–5.CrossRef
9.
go back to reference Zillich AJ, Blumenschein K, Johannesson M, Freeman P. Assessment of the relationship between measures of disease severity, quality of life, and willingness to pay in asthma. Pharmacoeconomics. 2002;20(4):257–65.CrossRef Zillich AJ, Blumenschein K, Johannesson M, Freeman P. Assessment of the relationship between measures of disease severity, quality of life, and willingness to pay in asthma. Pharmacoeconomics. 2002;20(4):257–65.CrossRef
10.
go back to reference Fonseca J, Delgado L, Costa-Pereira A, Tavares C, Moreira A, Morete A, et al. Evaluation of the Asthma Life Quality test for the screening and severity assessment of asthma. Allergy. 2004;59(11):1198–204.CrossRef Fonseca J, Delgado L, Costa-Pereira A, Tavares C, Moreira A, Morete A, et al. Evaluation of the Asthma Life Quality test for the screening and severity assessment of asthma. Allergy. 2004;59(11):1198–204.CrossRef
11.
go back to reference Mancuso CA, Peterson MG, Charlson ME. Effects of depressive symptoms on health-related quality of life in asthma patients. J Gen Intern Med. 2000;15(5):301–10.CrossRef Mancuso CA, Peterson MG, Charlson ME. Effects of depressive symptoms on health-related quality of life in asthma patients. J Gen Intern Med. 2000;15(5):301–10.CrossRef
12.
go back to reference Fonseca JA, Delgado L, Costa-Pereira A, Tavares C, Moreira A, Morete A, de Oliveira F, Rodrigues J, Vaz M. Evaluation of the Asthma Life Quality test for the screening and severity assessment of asthma. Allergy. 2004;59(11):1198–204.CrossRef Fonseca JA, Delgado L, Costa-Pereira A, Tavares C, Moreira A, Morete A, de Oliveira F, Rodrigues J, Vaz M. Evaluation of the Asthma Life Quality test for the screening and severity assessment of asthma. Allergy. 2004;59(11):1198–204.CrossRef
13.
go back to reference Juniper EF, Svensson K, Mörk AC, Ståhl E. Measurement properties and interpretation of three shortened versions of the asthma control questionnaire. Respir Med. 2005;99(5):553–8.CrossRef Juniper EF, Svensson K, Mörk AC, Ståhl E. Measurement properties and interpretation of three shortened versions of the asthma control questionnaire. Respir Med. 2005;99(5):553–8.CrossRef
14.
go back to reference Juniper EF, Bousquet J, Abetz L, Bateman ED, GOAL Committee. Identifying “well-controlled” and “not well-controlled” asthma using the Asthma Control Questionnaire. Respir Med. 2006;100(4):616–21.CrossRef Juniper EF, Bousquet J, Abetz L, Bateman ED, GOAL Committee. Identifying “well-controlled” and “not well-controlled” asthma using the Asthma Control Questionnaire. Respir Med. 2006;100(4):616–21.CrossRef
15.
go back to reference Juniper EF, Buist AS, Cox FM, Ferrie PJ, King DR. Validation of a standardized version of the Asthma Quality of Life Questionnaire. Chest. 1999;115(5):1265–70.CrossRef Juniper EF, Buist AS, Cox FM, Ferrie PJ, King DR. Validation of a standardized version of the Asthma Quality of Life Questionnaire. Chest. 1999;115(5):1265–70.CrossRef
16.
go back to reference Fazel N, Kundi M, Jensen-Jarolim E, Pali-Schöll I, Kazemzadeh A, Abdizadeh MF, et al. Prospective cohort study of pregnancy complications and birth outcomes in women with asthma. Arch Gynecol Obstet. 2018;298(2):279–87.CrossRef Fazel N, Kundi M, Jensen-Jarolim E, Pali-Schöll I, Kazemzadeh A, Abdizadeh MF, et al. Prospective cohort study of pregnancy complications and birth outcomes in women with asthma. Arch Gynecol Obstet. 2018;298(2):279–87.CrossRef
17.
go back to reference Pedram Razi S, Bassampour S, Kazemnejad A. Quality of life in asthmatic patients. J Hayat. 2007;13(1):29–34. Pedram Razi S, Bassampour S, Kazemnejad A. Quality of life in asthmatic patients. J Hayat. 2007;13(1):29–34.
18.
go back to reference Powell H, McCaffery K, Murphy VE, Hensley MJ, Clifton VL, Giles W, et al. Psychosocial outcomes are related to asthma control and quality of life in pregnant women with asthma. J Asthma. 2011;48(10):1032–40.CrossRef Powell H, McCaffery K, Murphy VE, Hensley MJ, Clifton VL, Giles W, et al. Psychosocial outcomes are related to asthma control and quality of life in pregnant women with asthma. J Asthma. 2011;48(10):1032–40.CrossRef
19.
go back to reference Burgess L, McCaffery K, Powell H, Murphy VE, Gibson PG, Turner RM. The influence of asthma control on psychosocial outcomes for pregnant women with asthma. J Asthma. 2015;52(10):1013–9.CrossRef Burgess L, McCaffery K, Powell H, Murphy VE, Gibson PG, Turner RM. The influence of asthma control on psychosocial outcomes for pregnant women with asthma. J Asthma. 2015;52(10):1013–9.CrossRef
21.
go back to reference Zairina E, Stewart K, Abramson MJ, George J. The effectiveness of non-pharmacological healthcare interventions for asthma management during pregnancy: a systematic review. BMC Pulm Med. 2014;14(1):1–8.CrossRef Zairina E, Stewart K, Abramson MJ, George J. The effectiveness of non-pharmacological healthcare interventions for asthma management during pregnancy: a systematic review. BMC Pulm Med. 2014;14(1):1–8.CrossRef
22.
go back to reference Bhargava S, Prakash A, Rehan HS, Gupta LK. Effect of systemic corticosteroids on serum apoptotic markers and quality of life in patients with asthma. Allergy Asthma Proc. 2015;36:275–82.CrossRef Bhargava S, Prakash A, Rehan HS, Gupta LK. Effect of systemic corticosteroids on serum apoptotic markers and quality of life in patients with asthma. Allergy Asthma Proc. 2015;36:275–82.CrossRef
23.
go back to reference Louik C, Schatz M, Hernández-Díaz S, Werler MM, Mitchell AA. Asthma in pregnancy and its pharmacologic treatment. Ann Allergy Asthma Immunol. 2010;105(2):110–7.CrossRef Louik C, Schatz M, Hernández-Díaz S, Werler MM, Mitchell AA. Asthma in pregnancy and its pharmacologic treatment. Ann Allergy Asthma Immunol. 2010;105(2):110–7.CrossRef
24.
go back to reference Peters JB, Rijssenbeek-Nouwens LH, Bron AO, Fieten KB, Weersink EJ, Bel EH, et al. Health status measurement in patients with severe asthma. Respir Med. 2014;108(2):278–86.CrossRef Peters JB, Rijssenbeek-Nouwens LH, Bron AO, Fieten KB, Weersink EJ, Bel EH, et al. Health status measurement in patients with severe asthma. Respir Med. 2014;108(2):278–86.CrossRef
25.
go back to reference Wilson SR, Rand CS, Cabana MD, Foggs MB, Halterman JS, Olson L, et al. Asthma outcomes: quality of life. J Allergy Clin Immunol. 2012;129(3):S88–123.CrossRef Wilson SR, Rand CS, Cabana MD, Foggs MB, Halterman JS, Olson L, et al. Asthma outcomes: quality of life. J Allergy Clin Immunol. 2012;129(3):S88–123.CrossRef
26.
go back to reference Namazy JA, Chambers C, Schatz M. Safety of therapeutic options for treating asthma in pregnancy. Expert Opin Drug Saf. 2014;13(12):1613–21.CrossRef Namazy JA, Chambers C, Schatz M. Safety of therapeutic options for treating asthma in pregnancy. Expert Opin Drug Saf. 2014;13(12):1613–21.CrossRef
27.
go back to reference Mathur SK, Viswanathan RK. Relevance of allergy in adult asthma. Curr Allergy Asthma Rep. 2014;14(5):437.CrossRef Mathur SK, Viswanathan RK. Relevance of allergy in adult asthma. Curr Allergy Asthma Rep. 2014;14(5):437.CrossRef
28.
go back to reference Labor S, Tir AMD, Plavec D, Juric I, Roglic M, Vukelic JP, et al. What is safe enough-asthma in pregnancy-a review of current literature and recommendations. Asthma Res Practi. 2018;4(1):1–9.CrossRef Labor S, Tir AMD, Plavec D, Juric I, Roglic M, Vukelic JP, et al. What is safe enough-asthma in pregnancy-a review of current literature and recommendations. Asthma Res Practi. 2018;4(1):1–9.CrossRef
Metadata
Title
Quality of life and asthma control in pregnant women with asthma
Authors
Nasrin Fazel
Michael Kundi
Erika Jensen-Jarolim
Isabella Maria Pali-Schöll
Asghar Kazemzadeh
Habibollah Esmaily
Mojtaba Fattahi Abdizadeh
Roya Akbarzadeh
Raheleh Ahmadi
Hossain Jabbari
Publication date
01-12-2021
Publisher
BioMed Central
Published in
BMC Pulmonary Medicine / Issue 1/2021
Electronic ISSN: 1471-2466
DOI
https://doi.org/10.1186/s12890-021-01797-9

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