Published in:
18-01-2024 | Bronchial Asthma | Editorial Commentary
Hypothalamic-Pituitary-Adrenal Axis Suppression with Inhaled Corticosteroids—Time to Close the Debate?
Author:
Anurag Bajpai
Published in:
Indian Journal of Pediatrics
|
Issue 5/2024
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Excerpt
Inhaled corticosteroids are one of the most used drugs in pediatric practice and the cornerstone of asthma management [
1]. While the benefits of inhaled corticosteroids in managing pediatric asthma cannot be over-emphasized, concern regarding its adverse effects impedes its wider use [
2]. Negative impacts on growth and bone health and suppression of the Hypothalamic-Pituitary-Adrenal (HPA) axis remain the leading causes of concern with prolonged inhaled corticosteroid treatment [
3]. There is a lack of information about the impact of inhaled corticosteroids on adrenal functions in Indian children and adolescents with bronchial asthma. …