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Indian Journal of Pediatrics
Published in: Indian Journal of Pediatrics 5/2024

13-01-2024 | Bronchial Asthma | Editorial Commentary

Metabolic Syndrome and Childhood Asthma: Association or Causation?

Authors: Jagdish Prasad Goyal, Kalyana Prabhakaran

Published in: Indian Journal of Pediatrics | Issue 5/2024

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Excerpt

Metabolic syndrome (MS) is closely linked to obesity and insulin resistance. Several epidemiological studies have attempted to find the robust link between MS and asthma control in children and it is still under debate. The crosstalk of adipokine imbalance and hyper-insulinemia with airway inflammation including hyperresponsiveness has been proposed as the probable mechanism along with other factors [1]. …
Literature
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Kuschnir FC, Felix MMR, Caetano Kuschnir MC, et al. Severe asthma is associated with metabolic syndrome in Brazilian adolescents. J Allergy Clin Immunol. 2018;141:1947–9.CrossRefPubMed
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Forno E, Han YY, Muzumdar RH, Celedón JC. Insulin resistance, metabolic syndrome, and lung function in US adolescents with and without asthma. J Allergy Clin Immunol. 2015;136:304–11.CrossRefPubMedPubMedCentral
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Cholakovska VC, Vlashki E, Stefanovska VV, Jovanovska AA, Jordanova O, Kochova M. Metabolic syndrome in children with asthma. Acad Med J. 2022;2:67–77.CrossRef
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von Mutius E, Schwartz J, Neas LM, Dockery D, Weiss ST. Relation of body mass index to asthma and atopy in children: the National Health and Nutrition Examination Study III. Thorax. 2001;56:835–8.
Metadata
Title
Metabolic Syndrome and Childhood Asthma: Association or Causation?
Authors
Jagdish Prasad Goyal
Kalyana Prabhakaran
Publication date
13-01-2024
Publisher
Springer India
Published in
Indian Journal of Pediatrics / Issue 5/2024
Print ISSN: 0019-5456
Electronic ISSN: 0973-7693
DOI
https://doi.org/10.1007/s12098-023-05018-5

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